Tandem ring-closing metathesis reaction with a ruthenium catalyst containing a N-heterocyclic ligand [PDF]
, 2001 The highly active catalyst 2 was used in tandem RCM to make molecules with various ring systems containing α,β-unsaturated carbonyl ...
Choi, Tae-Lim, Grubbs, Robert H.
core +1 more source
5-Chloro-6-oxo-6H-xantheno[4,3-d]thiazole-2-carbonitrile
Molbank, 2022 Xanthones and benzothiazoles are important classes of heterocyclic compounds with versatile biological activities. Herein, we describe a straightforward and scalable synthesis of 5-chloro-6-oxo-6H-xantheno[4,3-d]thiazole-2-carbonitrile, a thiazole-fused ...
Konstantinos Paraskevas +3 more
doaj +1 more source
Four Components One-Pot Synthesis of New Thiazoles and Their Biological Screening for Anti-Tuberculosis Activity [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 2023 Multi heterocyclic ring system shows a wide spectrum of pharmaceutical and biological activities. Novel series of 2-Benzyloxy-5-(2-{N'-[3-(substituted-phenyl)-1-phenyl-1H-pyrazol-4-ylmethylene]-hydrazino}-thiazol-4-yl)-benzoic acid methyl ester ...
Vijay Kadam +4 more
doaj +1 more source
Strategies against nonsense: oxadiazoles as translational readthrough-inducing drugs (TRIDs) [PDF]
, 2019 This review focuses on the use of oxadiazoles as translational readthrough-inducing drugs (TRIDs) to rescue the functional full-length protein expression in mendelian genetic diseases caused by nonsense mutations.
Campofelice A. +6 more
core +1 more source
Molecules, 2015 Triazole derivatives constitute an important group of heterocyclic compounds have have been the subject of extensive study in the recent past. These compounds have shown a wide range of biological and pharmacological activities.
Lidija Kosychova +6 more
doaj +1 more source
An electron-deficient triosmium cluster containing the thianthrene ligand: Synthesis, structure and reactivity of [Os₃(CO)₉(μ3-η2-C₁₂H₇S₂)(μ-H)] [PDF]
, 2008 Reaction of [Os₃(CO)₁₀(CH₃CN)₂] with thianthrene at 80 °C leads to the nonacarbonyl dihydride compound [Os₃(CO)₉(μ-3,4-η²-C₁₂H₆S₂)(μ-H)₂] (1) and the 46-electron monohydride compound [Os₃(CO)₉(μ₃-η²-C₁₂H₇S₂)(μ-H)] (2).
Hassan, Mohammad R. +7 more
core +1 more source
Crystal structures of two 6-(2-hydroxybenzoyl)-5H-thiazolo[3,2-a]pyrimidin-5-ones
Acta Crystallographica Section E: Crystallographic Communications, 2015 The title compounds, 6-(2-hydroxybenzyl)-5H-thiazolo[3,2-a]pyrimidin-5-one, C13H8N2O3S, (1), and 6-(2-hydroxybenzyl)-3-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one, C14H10N2O3S, (2), were synthesized when a chromone-3-carboxylic acid, activated with ...
Ligia R. Gomes +3 more
doaj +1 more source
Molecules, 2023 Progesterone injection is oily because of its poor solubility. It is necessary to develop new dosage forms or delivery methods for Progesterone. Six cocrystals of Progesterone with nitrogen heterocyclic compounds (2,6-diaminopyridine, isonicotinamide, 4 ...
Juan Xu, Wei Gao, Qi Zhang, Lifeng Ning
doaj +1 more source
Synthesis and Characterization of Some Compounds containing Pyrazole Moiety [PDF]
مجلة جامعة الانبار للعلوم الصرفة, 2018 This study includes the preparation of some heterocyclic compounds compact of the Pyrazole, work is done in three steps. First step, treatment of acetophenone derivatives with DMF-DMA for the preparation of the first compound (2E)-1-( R phenyl)-3 ...
Samer M. Tayib +1 more
doaj +1 more source
1,6-Naphthyridin-2(1H)-ones: Synthesis and Biomedical Applications
Pharmaceuticals, 2021 Naphthyridines, also known as diazanaphthalenes, are a group of heterocyclic compounds that include six isomeric bicyclic systems containing two pyridine rings.
Juan Marcos Oliveras +4 more
doaj +1 more source