Results 211 to 220 of about 176,899 (357)

Interrupted Barton–Zard Reaction/Friedel–Crafts Alkylation Telescoped Reaction for the Synthesis of Pyrrolo[3,4‐b]indole Cores

Asian Journal of Organic Chemistry, EarlyView.
An interrupted Barton–Zard reaction/Friedel–Crafts alkylation telescoped reaction provides aryl‐substituted pyrrolo[3,4‐b] cores in moderate‐to‐good yields as mostly single diastereomers. The reaction is tolerant of a wide range of electron‐deficient indoles and (hetero)aromatic nucleophiles, offering a modular approach for the synthesis of multi ...
Josip Rešetar, Karla Remar, Ana Mikleušević, Josipa Suć Sajko, Ines Bašić, Matija Gredičak   +5 more
wiley   +1 more source

Scalable Main Group Mechanocatalytic CO2 Valorisation to Cyclocarbonate Species

Angewandte Chemie, EarlyView.
Herein, we present a scalable mechanocatalytic method for synthesizing cyclic carbonates from solid and liquid epoxides using CO₂ at 1 bar and room temperature. Employing a gallium aminotrisphenolate catalyst, this process achieves high yields, efficiently transforms multi‐terminal epoxides, and outperforms solution‐based methods in green metrics ...
Javier F. Reynes, Lucia Álvarez‐Miguel, F. Winkelmann, M. Felderhoff, Marta E. G. Mosquera, Christopher J. Whiteoak, Felipe García   +6 more
wiley   +2 more sources

Therapeutic Role of Heterocyclic Compounds in Neurodegenerative Diseases: Insights from Alzheimer's and Parkinson's Diseases. [PDF]

Neurol Int
Puranik N, Song M.
europepmc   +1 more source

Therapeutic Potential of Heterocyclic Compounds Targeting Mitochondrial Calcium Homeostasis and Signaling in Alzheimer's Disease and Parkinson's Disease. [PDF]

Antioxidants (Basel), 2023
Tapias V, González-Andrés P, Peña LF, Barbero A, Núñez L, Villalobos C.   +5 more
europepmc   +1 more source

Studies on the Infrared Spectra of Heterocyclic Compounds. III. Infrared Spectra of Alkylpyridine 1-Oxides.

, 1956
HIDEYO SHINDO
openalex   +2 more sources

Advances on Albumin‐Based Carriers for Anticancer Drug Delivery

Advanced NanoBiomed Research, EarlyView.
This study systematically classifies the drug delivery modes of albumin by examining the characteristics of its surface‐active groups and internal binding sites. It provides an in‐depth analysis of various drug delivery strategies and their corresponding targeting mechanisms.
Ruoli Zhou, Rongbin Zhong, Zhonghui Luo, Hua Wei, Cui‐Yun Yu   +4 more
wiley   +1 more source

An updated review of fatty acid residue-tethered heterocyclic compounds: synthetic strategies and biological significance. [PDF]

RSC Adv, 2023
Majrashi TA, Sabt A, Abd El Salam HA, Al-Ansary GH, Hamissa MF, Eldehna WM.   +5 more
europepmc   +1 more source

Heterocyclic compounds derived from 5- and 8-aminoquinolines

, 1938
Gordon Kingsley Hughes, Stanley J Hazlewood, Francis Lions   +2 more
openalex   +2 more sources

Ortho-Amido-phenylhydrazine and some Interesting Heterocyclic Compounds derived from it. [PDF]

, 1925
PRAPHULLA CHANDRA GUHA, SUDHANYA KUMAR RAY   +1 more
openalex   +1 more source

Mitigating Molecular Aggregation in Drug Discovery With Predictive Insights From Explainable AI

Angewandte Chemie, EarlyView.
In this work, MEGAN, our explainable AI model, is applied to predict small colloidally aggregating molecules (SCAMs), a significant source of false positives in drug discovery. MEGAN provides interpretable predictions and proposes structurally similar, non‐aggregating alternative molecules.
Hunter Sturm, Jonas Teufel, Kaitlin A. Isfeld, Pascal Friederich, Rebecca L. Davis   +4 more
wiley   +2 more sources