Results 61 to 70 of about 3,737,155 (255)

Post-Ugi Cyclization for the Construction of Diverse Heterocyclic Compounds: Recent Updates

Frontiers in Chemistry, 2018
Multicomponent reactions (MCRs) have proved as a valuable tool for organic and medicinal chemist because of their ability to introduce a large degree of chemical diversity in the product in a single step and with high atom economy.
Jitender Bariwal, R. Kaur, L. Voskressensky, E. V. Van der Eycken   +3 more
semanticscholar   +1 more source

In Situ Lipoprotein‐seeking Dye for in Vivo Real‐Time Imaging of Lipid Dysregulation Diseases

Advanced Science, EarlyView.
This study develops lipoprotein‐seeking NIR‐II dyes that specifically bind circulating lipoproteins. These dyes form ultra‐stable complexes with endogenous lipoprotein, enabling real‐time, high‐contrast imaging of fatty liver and atherosclerotic plaques. Tunable binding kinetics allow customized imaging windows.
Yijing Du, Zetao Dang, Baofeng Xu, Jiajun Xu, Dan Wang, Yuewei Zhang, Shoujun Zhu   +6 more
wiley   +1 more source

Crystal structures of N-[(4-phenylthiazol-2-yl)carbamothioyl]benzamide and N-{[4-(4-bromophenyl)thiazol-2-yl]carbamothioyl}benzamide from synchrotron X-ray diffraction

Acta Crystallographica Section E: Crystallographic Communications, 2016
The title compounds, C17H13N3OS2, (I), and C17H12BrN3OS2, (II), are potential active pharmaceutical ingredients. Compound (I) comprises two almost planar fragments. The first is the central (carbamothioyl)amide (r.m.s.
Ekaterina S. Gantimurova, Alexander S. Bunev, Kristina Yu. Talina, Gennady I. Ostapenko, Pavel V. Dorovatovskii, Nikolai N. Lobanov, Victor N. Khrustalev   +6 more
doaj   +1 more source

The Role of Ionic Liquids at the Biological Interfaces in Bioelectronics

Advanced Science, EarlyView.
Ionic liquids (ILs) are highlighted as key artificial ionic materials that bridge biological ion‐based signaling and electronic devices. By understanding their composition, structure, function relationships, and mechanisms, ILs can advance from high performance electrolyte to core materials enabling integrated, multifunctional bioelectronics for ...
Yeong‐sinn Ye, Young Jin Jo, Ji Yeon Oh, Ju Yeon Jeong, Lili Guo, Tae‐il Kim   +5 more
wiley   +1 more source

Nano ordered polyacrylonitrile-grafted chitosan as a robust biopolymeric catalyst for efficient synthesis of highly substituted pyrrole derivatives

Scientific Reports
A novel heterogeneous nanocatalyst was developed using chitosan, as a natural polysaccharide derived from crustacean shells, and its in-situ grafting by polyacrylonitrile to afford nano ordered polyacrylonitrile-modified chitosan (CS-g-PAN). The obtained
Mahsa Zohrehvand, Niloufar Nashibi, Mohammad G. Dekamin, Afshin Sarvary   +3 more
doaj   +1 more source

A review on biological and medicinal impact of heterocyclic compounds

Results in Chemistry, 2022
E. Kabir, M. Uzzaman
semanticscholar   +1 more source

TTNPB Promotes Human Pluripotent Stem Cell‐to‐Neural Stem Cell Transition via Modulation of Chromatin Accessibility and the S‐(5′‐adenosyl)‐L‐homocysteine/Choline Metabolic Network

Advanced Science, EarlyView.
A retinoic acid receptor agonist, TTNPB, drives the efficient generation of advanced neural stem cells (ANSCs) from human pluripotent stem cells. TTNPB‐centered chromatin remodeling and metabolic reprogramming, promote neuroectoderm commitment. The resulting cells show robust neural potential and functional efficacy in a rat depression model.
Ruilin Du, Yudi Ren, Qiaoqiao Meng, Peng Wei, Ruyu Zhu, Junjie Bao, Ye Yang, Shuo Yan, Chaorong Yue, Xueying Zhu, Shuo Cao, Chunxia Hao, Wei Sun, Yongli Song, Xihe Li, Zhimin Wu, Siqin Bao, Yanglin Chen   +17 more
wiley   +1 more source

Direct Electrochemistry of Glucose Oxidase on a GrapheneGraphene Oxide Nanocomposite-Modified Electrode for a Glucose Biosensor

International Journal of Electrochemical Science, 2019
Direct electrochemistry of glucose oxidase (GOD) was conducted on the surface of a novel graphenegraphene oxide (GR-GO) nanocomposite. GR-GO possesses the virtues of excellent biocompatibility and conductivity, and high sensitivity to local perturbations,
Bo Wang, Xiaoli Wang, Zhifang He, Xiufeng Zhao, Linyu Wang   +4 more
doaj   +1 more source

Spatially Resolved Multiomics Reveals Metabolic Remodeling and Autophagy Activation in Adamantinomatous Craniopharyngiomas

Advanced Science, EarlyView.
Multiomics integration analysis reveals the “cystic fluid–tumor cell” metabolic coupling that mediates active choline/ethanolamine uptake of tumor cells from cystic fluid and PC/PE synthesis pathways reprogramming that mediating autophagy pathway activation within ACP. ABSTRACT Adamantinomatous craniopharyngioma (ACP), a benign yet highly recurrent and
Dongting Chen, Yahui Gao, Yulin Wang, Ting Lei, Zheng Qu, Yuhan An, Jiaxu Fu, Xin Li, Fangjun Liu, Yan Li   +9 more
wiley   +1 more source

Self‐Sustaining Piezozyme Platform for Antifouling via Mechanically Triggered Enzymatic Cascade

Advanced Science, EarlyView.
Wave‐powered CeO2/g‐C3N4 piezozyme coating converts ocean motion into an enzymatic H2O2‐to‐ROS cascade, realizing 180‐day eco‐friendly marine antifouling. ABSTRACT Harnessing ubiquitous mechanical energy for catalytic activation offers an emerging pathway toward self‐sustaining environmental protection systems.
Jingyu Wang, Yanjun Yu, Rongxin Su, Jiangjiexing Wu   +3 more
wiley   +1 more source