Results 11 to 20 of about 38,755 (208)

Heterogeneous nuclear ribonucleoprotein L facilitates recruitment of 53BP1 and BRCA1 at the DNA break sites induced by oxaliplatin in colorectal cancer [PDF]

Cell Death and Disease, 2019
Although oxaliplatin is an effective chemotherapeutic drug for treatment of colorectal cancer (CRC), tumor cells can develop mechanisms to evade oxaliplatin-induced cell death and show high tolerance and acquired resistance to this drug.
Wenjun Hu, Linping Lei, Xuqin Xie, Libin Huang, Qian Cui, T. Dang, Gang L Liu, Yuan Li, Xiao-Feng Sun, Zongguang Zhou   +9 more
semanticscholar   +2 more sources

The RNA binding protein hnRNP A/B controls exosomal miR-27a-5p loading during Salmonella infection [PDF]

Poultry Science
Salmonella infections cause significant economic losses in poultry and livestock production. Salmonella infection reprograms the proteomic and miRNA profiles of intestinal macrophage-derived exosomes, which subsequently modulates the inflammatory ...
Mingjuan Qu, Jianlong Zhang, Xin Yu, Linlin Jiang, Hongwei Zhu, Xingxiao Zhang   +5 more
doaj   +2 more sources

An Arrayed Genome-Wide Perturbation Screen Identifies the Ribonucleoprotein hnRNP K As Rate-Limiting for Prion Propagation [PDF]

, 2022
A defining characteristic of mammalian prions is their capacity for self-sustained propagation. Theoretical considerations and experimental evidence suggest that prion propagation is modulated by cell-autonomous and non-autonomous modifiers.
Chincisan, Andra; https://orcid.org/, Sellitto, Stefano, Losa, Marco; https://orcid.org/, Heinzer, Daniel; https://orcid.org/, Aguzzi, Adriano; https://orcid.org/, Pease, Daniel P; https://orcid.org/, Avar, Merve; https://orcid.org/, Pease, Daniel Patrick; https://orcid.org/, Hornemann, Simone; https://orcid.org/, Emmenegger, Marc; https://orcid.org/, Yin, Jiang-An; https://orcid.org/, Hornemann, Simone Alexandra; https://orcid.org/, Lakkaraju, Asvin K K, Thackray, Alana M; https://orcid.org/, Liu, Yingjun; https://orcid.org/, Thackray, Alana M, Hruska-Plochan, Marian; https://orcid.org/, Hruska‐Plochan, Marian; https://orcid.org/, Lakkaraju, Asvin KK; https://orcid.org/, Sellitto, Stefano; https://orcid.org/, Yin, Jiang‐An; https://orcid.org/, Polymenidou, Magdalini; https://orcid.org/, Bujdoso, Raymond, Schaper, Elke; https://orcid.org/   +23 more
core   +1 more source

Heterogeneous nuclear ribonucleoprotein A3, a novel RNA trafficking response element-binding protein [PDF]

, 2002
The cis-acting response element, A2RE, which is sufficient for cytoplasmic mRNA trafficking in oligodendrocytes, binds a small group of rat brain proteins.
Snee, Mark J., Shan, Jianguo, Ma, Alice S. W., Smith, Ross, Munro, Trent P., Hoek, Keith S., Moran-Jones, Kim   +6 more
core   +1 more source

Heterogeneous nuclear ribonucleoprotein A1 regulates rhythmic synthesis of mouse Nfil3 protein via IRES-mediated translation. [PDF]

, 2018
Nuclear factor, interleukin 3, regulated (Nfil3, also known as E4 Promoter-Binding Protein 4 (E4BP4)) protein is a transcription factor that binds to DNA and generally represses target gene expression.
Ji-Young Seo, Kim, K.-T., Lee, K.-H, HyeGuk Ryu, Lee, Hwa-Rim, Hyo-Jin Kim, Kim, D.-Y   +6 more
core   +1 more source

Heterogeneous nuclear ribonucleoprotein G-T (HNRNP G-T) mutations in men with impaired spermatogenesis [PDF]

, 2004
The genetic cause of male subfertility due to impaired spermatogenesis is unknown in the majority of cases, but the general assumption is that it is a complex disorder.
Lombardi, M. P., van der Veen, F., Gianotten, J., Leschot, N. J., Repping, S., Westerveld, G. H.   +5 more
core   +1 more source

Nuclear AURKA acquires kinase-independent transactivating function to enhance breast cancer stem cell phenotype. [PDF]

, 2015
Centrosome-localized mitotic Aurora kinase A (AURKA) facilitates G2/M events. Here we show that AURKA translocates to the nucleus and causes distinct oncogenic properties in malignant cells by enhancing breast cancer stem cell (BCSC) phenotype ...
Wang, X, Shi, Q, Yuan, Z, Cheng, W, Liu, Q, Li, G, Zheng, F, Lam, EW, Long, Z, Qiu, W, Hung, MC, He, B, Xu, J, Yue, C, Yan, M, Liu, B   +15 more
core   +3 more sources

ANTI-HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN B1 (ANTI-RA33) ANTIBODIES IN RHEUMATOID ARTHRITIS AND SYSTEMIC SCLEROSIS [PDF]

, 2017
Anti-heterogeneous nuclear ribonucleoprotein (RNP) autoantibodies (AAbs) are encountered in many autoimmune rheumatic diseases (ARDs). The potential diagnostic value of the RA33 AAb complex consisting of RNP A2 and alternative domains of the splicing ...
O. Yu. Tkachenko, P. A. Kuznetsova, A. L. Maslyansky, V. I. Mazurov, S. V. Lapin   +4 more
core   +2 more sources

Screening of new candidate biomarkers for gestational diabetes mellitus

Huli yanjiu, 2022
ObjectiveTo screen out the candidate biomarkers of GDM by detecting the expression of placental differentially expressed proteins screened and verified by a previous study， which provided a direction for the exploration of biomarkers and new treatment ...
HUANG Pingping, GE Li, MIAO Haiyan, YU Honghong, WU Dongmei, LAI Yuting, JIANG Xinyong, WANG Guandong, CHEN Fan   +8 more
doaj  

Effect of heterogeneous nuclear ribonucleoprotein U on the migration and proliferation of non-small cell lung cancer cells [PDF]

精准医学杂志
Objective To investigate the effect of heterogeneous nuclear ribonucleoprotein U (hnRNP U) on the migration and proliferation of non-small cell lung cancer (NSCLC) cells.
HE Yangfan, XU Xiaorong, YU Xin, LIU Chunyan, LI Bing
doaj   +1 more source