Results 51 to 60 of about 29,124 (213)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

A molecular dynamics study of heterogeneous nucleation in generic liquid/substrate systems with positive lattice misfit

open access: yesMaterials Research Express, 2020
Nucleation plays a critical role in many natural and technological processes, and nucleation control requires detailed understanding of nucleation process at atomic level.
Z Fan, H Men
doaj   +1 more source

Ice nucleation from aqueous NaCl droplets with and without marine diatoms [PDF]

open access: yesAtmospheric Chemistry and Physics, 2011
Ice formation in the atmosphere by homogeneous and heterogeneous nucleation is one of the least understood processes in cloud microphysics and climate. Here we describe our investigation of the marine environment as a potential source of atmospheric IN ...
P. A. Alpert, J. Y. Aller, D. A. Knopf
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Homogeneous vs. heterogeneous nucleation in water-dicarboxylic acid systems [PDF]

open access: yesAtmospheric Chemistry and Physics, 2009
Binary heterogeneous nucleation of water-succinic/glutaric/malonic/adipic acid on nanometer-sized particles is investigated within the frame of classical heterogeneous nucleation theory. Homogeneous nucleation is also included for comparison. It is found
A. I. Hienola   +3 more
doaj  

Microstructural Evolution and Vacancy Defect Formation in Mn–Mo–Ni RPV Steel Under Low Cycle Fatigue: Insights From EBSD and PALS

open access: yesAdvanced Engineering Materials, EarlyView.
Low‐cycle fatigue damage in Mn–Mo–Ni reactor pressure vessel steel is examined using a combined electron backscatter diffraction and positron annihilation lifetime spectroscopy approach. The study correlates texture evolution, dislocation substructure development, and vacancy‐type defect formation across uniform, necked, and fracture regions, providing
Apu Sarkar   +2 more
wiley   +1 more source

Thermodynamic Pathways of Nonequilibrium Solidification in Wire‐Arc Additive Manufacturing Fe‐Based Multicomponent Alloy Structures

open access: yesAdvanced Engineering Materials, EarlyView.
Geometry‐driven thermal behavior in wire‐arc additive manufacturing (WAAM) influences microstructural evolution during nonequilibrium solidification of a chemically complex Fe–Cr–Nb–W–Mo–C nanocomposite system. By comparing different deposits configurations, distinct entropy–cooling rate correlations, segregation, and carbide evolution are revealed ...
Blanca Palacios   +5 more
wiley   +1 more source

Temperature-gradient effects on heterogeneous ice nucleation from supercooled water

open access: yesAIP Advances, 2019
Investigating the nucleation and freezing behavior of supercooled water under temperature gradients is of significance for theoretical research and practical application.
Liping Wang   +3 more
doaj   +1 more source

Influence of Scan Strategies in Electron Beam Powder Bed Fusion on Solidification, Microstructure, and High‐Temperature Compressive Properties of γ′‐Strengthened Inconel 738LC

open access: yesAdvanced Engineering Materials, EarlyView.
Experiments and thermophysical simulations were conducted to investigate the electron beam powder bed fusion electron beam (PBF‐EB/M) process for the γ′‐strengthened nickel‐based superalloy Inconel 738LC. The results demonstrate the impact of process‐induced microstructural variations on high‐temperature mechanical behavior, providing a basis for ...
Jan Niklas Petenati   +11 more
wiley   +1 more source

Effect of substrate micro-morphology on heterogeneous nucleation [PDF]

open access: yesChina Foundry, 2012
The heterogeneous nucleation process of NH4Cl crystals from a NH4Cl-70wt.%H2O solution on rough chilling substrates was considered in this paper. Scratched and etched substrates of aluminum were prepared with different surface morphologies.
Zhang Ying, Wang Meng, Liu Xin
doaj  

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