Results 151 to 160 of about 280,719 (209)

Heterologous AD5-nCOV plus CoronaVac versus homologous CoronaVac vaccination: a randomized phase 4 trial

open access: yesNature Medicine, 2022
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants and the waning of vaccine-elicited neutralizing antibodies suggests that additional coronavirus disease 2019 (COVID-19) vaccine doses may be needed for individuals who
Jingxin Li, Lihua Hou, Shipo Wu
exaly   +2 more sources
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Heterologous vaccine effects

Vaccine, 2016
The heterologous or non-specific effects (NSEs) of vaccines, at times defined as "off-target effects" suggest that they can affect the immune response to organisms other than their pathogen-specific intended purpose. These NSEs have been the subject of clinical, immunological and epidemiological studies and are increasingly recognized as an important ...
Mitra Saadatian-Elahi   +8 more
openaire   +3 more sources

Trained immunity-related vaccines: innate immune memory and heterologous protection against infections.

Trends in Molecular Medicine, 2022
The innate immune system is able to build memory-like features in response to certain infections or vaccines, resulting in enhanced responsiveness upon (re)challenge with the same or an unrelated pathogen, a phenomenon termed 'trained immunity'. Compared
Athanasios Ziogas, M. Netea
semanticscholar   +1 more source

Heterologicality and Incompleteness

MLQ, 2002
For a theory \(T\) containing ZF, the author presents a semantic proof of the following: if \(T\) has a model, then \(T+\neg \text{Con}_T\) has a model. This is a version of Gödel's Second Incompleteness Theorem. The author remarks it is equivalent to the usual version, provided that one has the derivability conditions characterizing provability in \(T\
openaire   +2 more sources

Recent advances in heterologous expression of natural product biosynthetic gene clusters in Streptomyces hosts.

Current Opinion in Biotechnology, 2021
The heterologous expression of natural product biosynthetic gene clusters (BGCs) has traditionally been used as a genetic platform to link various natural product chemotypes to their corresponding genotypes.
Hahk-Soo Kang, Eung-Soo Kim
semanticscholar   +1 more source

Generation of a cluster-free Streptomyces albus chassis strains for improved heterologous expression of secondary metabolite clusters.

Metabolic Engineering, 2018
Natural products are a rich source of potential drugs for many applications. Discovery of natural products through the activation of cryptic gene clusters encoding their biosynthetic pathways, engineering of those biosynthetic pathways and optimization ...
Maksym Myronovskyi   +5 more
semanticscholar   +1 more source

Tolerance to Heterologous Erythrocytes

Science, 1974
Injection of a water-soluble nonantigenic fraction obtained from lysed sheep red blood cells virtually abolishes the subsequent immune response to the red cells. The suppression is systemic and appears to be serum mediated.
R, Auerbach, J, Roethle
openaire   +2 more sources

Heterologous Parabiosis

Archives of Surgery, 1964
M E, VANCIL, C A, HARDIN
openaire   +2 more sources

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