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The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants and the waning of vaccine-elicited neutralizing antibodies suggests that additional coronavirus disease 2019 (COVID-19) vaccine doses may be needed for individuals who
Jingxin Li, Lihua Hou, Shipo Wu
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SARS-CoV-2-derived peptides define heterologous and COVID-19-induced T cell recognition
Nature Immunology, 2020Annika Nelde +2 more
exaly +2 more sources
Vaccine, 2016
The heterologous or non-specific effects (NSEs) of vaccines, at times defined as "off-target effects" suggest that they can affect the immune response to organisms other than their pathogen-specific intended purpose. These NSEs have been the subject of clinical, immunological and epidemiological studies and are increasingly recognized as an important ...
Mitra Saadatian-Elahi +8 more
openaire +3 more sources
The heterologous or non-specific effects (NSEs) of vaccines, at times defined as "off-target effects" suggest that they can affect the immune response to organisms other than their pathogen-specific intended purpose. These NSEs have been the subject of clinical, immunological and epidemiological studies and are increasingly recognized as an important ...
Mitra Saadatian-Elahi +8 more
openaire +3 more sources
Trends in Molecular Medicine, 2022
The innate immune system is able to build memory-like features in response to certain infections or vaccines, resulting in enhanced responsiveness upon (re)challenge with the same or an unrelated pathogen, a phenomenon termed 'trained immunity'. Compared
Athanasios Ziogas, M. Netea
semanticscholar +1 more source
The innate immune system is able to build memory-like features in response to certain infections or vaccines, resulting in enhanced responsiveness upon (re)challenge with the same or an unrelated pathogen, a phenomenon termed 'trained immunity'. Compared
Athanasios Ziogas, M. Netea
semanticscholar +1 more source
Heterologicality and Incompleteness
MLQ, 2002For a theory \(T\) containing ZF, the author presents a semantic proof of the following: if \(T\) has a model, then \(T+\neg \text{Con}_T\) has a model. This is a version of Gödel's Second Incompleteness Theorem. The author remarks it is equivalent to the usual version, provided that one has the derivability conditions characterizing provability in \(T\
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Current Opinion in Biotechnology, 2021
The heterologous expression of natural product biosynthetic gene clusters (BGCs) has traditionally been used as a genetic platform to link various natural product chemotypes to their corresponding genotypes.
Hahk-Soo Kang, Eung-Soo Kim
semanticscholar +1 more source
The heterologous expression of natural product biosynthetic gene clusters (BGCs) has traditionally been used as a genetic platform to link various natural product chemotypes to their corresponding genotypes.
Hahk-Soo Kang, Eung-Soo Kim
semanticscholar +1 more source
Metabolic Engineering, 2018
Natural products are a rich source of potential drugs for many applications. Discovery of natural products through the activation of cryptic gene clusters encoding their biosynthetic pathways, engineering of those biosynthetic pathways and optimization ...
Maksym Myronovskyi +5 more
semanticscholar +1 more source
Natural products are a rich source of potential drugs for many applications. Discovery of natural products through the activation of cryptic gene clusters encoding their biosynthetic pathways, engineering of those biosynthetic pathways and optimization ...
Maksym Myronovskyi +5 more
semanticscholar +1 more source
Tolerance to Heterologous Erythrocytes
Science, 1974Injection of a water-soluble nonantigenic fraction obtained from lysed sheep red blood cells virtually abolishes the subsequent immune response to the red cells. The suppression is systemic and appears to be serum mediated.
R, Auerbach, J, Roethle
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New heterologous modules for classical or PCR‐based gene disruptions in Saccharomyces cerevisiae
Yeast, 1994A. Wach +3 more
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