Results 171 to 180 of about 361,202 (360)

Diversity, transfer potential, and transcriptional activity of virus‐carried antibiotic resistance genes in global estuaries

open access: yesiMetaOmics, EarlyView.
Estuaries are vital hotspots for antibiotic resistance genes (ARGs) due to substantial antibiotic pollution. Although viruses have been proposed as key reservoirs and important disseminators of ARGs in environments, their contribution to the estuarine antibiotic resistome remains largely unknown.
Xiao‑Qing Luo   +9 more
wiley   +1 more source

Identification of Clinical Factors Associated With the Immunogenicity of Homologous ChAdOx1‐nCoV‐19 Vaccine in Hemodialysis Patients

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Hemodialysis (HD) patients are at higher risk of severe COVID‐19 and may exhibit suboptimal vaccine responses. This study evaluates the factors influencing vaccine‐induced immunity in HD patients following the second dose of the Vaxzevria. A total of 276 HD patients and 126 controls were included. Antibody responses were assessed using binding
Chia‐Wei Chang   +9 more
wiley   +1 more source

Beyond PD‐1/PD‐L1: New Immune Checkpoints and Therapeutic Combinations in Cancer Immunotherapy

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT Recently, immune checkpoint inhibitors (ICIs), particularly PD‐1/PD‐L1 and CTLA‐4 inhibitors, have revolutionized cancer treatment, significantly improving survival rates for various malignancies. However, ICI therapies targeting single checkpoints on T cells still face numerous challenges, such as low response rates and post‐treatment ...
Yangyang Li, Zizhen Kang, Yanyun Du
wiley   +1 more source

Ethical concerns regarding heterologous COVID-19 vaccine administration

open access: yesHuman Vaccines & Immunotherapeutics
Somsri Wiwanitkit, Viroj Wiwanitkit
doaj   +1 more source

Molecular Relationship Between Ovarian Sertoli-Leydig Cell Tumors and Their Heterologous Elements: Emphasis on the Possible Prognostic Significance of TERT Pathogenic Variants. [PDF]

open access: yesAm J Surg Pathol
Trecourt A   +15 more
europepmc   +1 more source

Calcium signaling in plant defense

open access: yesNew Plant Protection, EarlyView.
Calcium signaling acts as a central hub in plant immunity, translating pathogen perception into defense responses. This review highlights the channels, sensors, and signaling networks involved, and discusses how pathogens subvert calcium dynamics, as well as how this knowledge may inspire innovative strategies for engineering durable crop resistance ...
Lifan Sun, Yu Wang, Jie Zhang
wiley   +1 more source

Isolation of a laccase-coding gene from the lignin-degrading fungusPhlebia brevisporaBAFC 633 and heterologous expression inPichia pastoris [PDF]

open access: bronze, 2018
María Isabel Fonseca   +6 more
openalex   +1 more source

The Cinderella tree, Quillaja saponaria – A soap story

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Our current understanding of plants has been shaped by the entwining of different cultures. The Chilean soapbark tree, traditionally valued as a source of natural soap, was shown by serendipitous research in France in the 1900s to produce compounds that can boost the immune response to vaccines.
Anne Osbourn
wiley   +1 more source

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