Results 71 to 80 of about 434,960 (396)

Rational construction of genome-reduced Burkholderiales chassis facilitates efficient heterologous production of natural products from proteobacteria

open access: yesNature Communications, 2021
Heterologous expression of biosynthetic gene clusters (BGCs) avails yield improvements and mining of natural products, but it is limited by lacking of more efficient Gram-negative chassis.
Jiaqi Liu   +15 more
semanticscholar   +1 more source

BNT162b2 COVID-19 vaccination in children alters cytokine responses to heterologous pathogens and Toll-like receptor agonists

open access: yesFrontiers in Immunology, 2023
BackgroundVaccines can have beneficial off-target (heterologous) effects that alter immune responses to, and protect against, unrelated infections. The heterologous effects of COVID-19 vaccines have not been investigated in children.AimTo investigate ...
Andrés Noé   +17 more
doaj   +1 more source

A condition-specific codon optimization approach for improved heterologous gene expression in Saccharomyces cerevisiae [PDF]

open access: yes, 2014
All authors are with the Department of Chemical Engineering, The University of Texas at Austin, 200 E Dean Keeton St. Stop C0400, Austin, TX 78712, USA -- Hal S.
Alper, Hal S.   +3 more
core   +3 more sources

ON HETEROLOGOUS STRUMA OF THE KIDNEYS [PDF]

open access: yesThe American Journal of the Medical Sciences, 1889
n ...
openaire   +1 more source

Interaction of class III cellobiose dehydrogenase with lytic polysaccharide monooxygenase

open access: yesFEBS Open Bio, EarlyView.
The activity of lytic polysaccharide monooxygenase (LPMO) is supported by its auxiliary enzyme cellobiose dehydrogenase (CDH). The catalytic activity of both enzymes is coupled by electron transfer and a cyclic cascade generating substrates for both enzymes – hydrogen peroxide for LPMO and oxidized and non‐oxidized cellobiose and cello‐oligosaccharide ...
Angela Giorgianni   +4 more
wiley   +1 more source

Heterologous Expression of an Insecticidal Peptide Obtained from the Transcriptome of the Colombian Spider Phoneutria depilate

open access: yesToxins, 2023
Spider venoms are composed, among other substances, of peptide toxins whose selectivity for certain physiological targets has made them powerful tools for applications such as bioinsecticides, analgesics, antiarrhythmics, antibacterials, antifungals and ...
Julieta Vásquez-Escobar   +7 more
doaj   +1 more source

Pathogenesis and antigenic characterization of a new East European subtype 3 porcine reproductive and respiratory syndrome virus isolate [PDF]

open access: yes, 2010
Background: Porcine reproductive and respiratory syndrome virus (PRRSV) is divided into a European and North American genotype. East European PRRSV isolates have been found to be of the European genotype, but form different subtypes. In the present study,
Geldhof, Marc   +5 more
core   +2 more sources

Heterologous Antilymphocyte Globulin [PDF]

open access: yesNew England Journal of Medicine, 1968
THE immunosuppressive properties of heterologous antilymphocyte serum and its globulin derivative have been well known since 1961, when it was reported that a variety of immunologic responses could...
openaire   +3 more sources

Heterologous expression of human transketolase [PDF]

open access: yesThe International Journal of Biochemistry & Cell Biology, 1998
Transketolase belongs to the family of thiamin diphosphate dependent enzymes. The aim of this study was to establish a bacterial expression system for human transketolase in order to investigate the functional characteristics of mammalian transketolases. The level of recombinant human enzyme expressed in Escherichia coli was modest.
Schenk, Gerhard   +2 more
openaire   +5 more sources

NMR screening of low molecular weight inhibitors targeting the papain‐like protease (PLPro) of SARS‐CoV‐2

open access: yesFEBS Open Bio, EarlyView.
Papain‐like protease from SARS‐CoV‐2 plays an important role in the cleavage of the viral polyproteins and in the suppression of the host's immune response. Here, we present the results of an NMR screening study. We identified 86 binding compounds, of which five candidates were chosen for in‐depth analysis.
Dennis J. Pyper   +5 more
wiley   +1 more source

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