Results 11 to 20 of about 145,939 (263)
Modelling hCDKL5 Heterologous Expression in Bacteria [PDF]
Metabolites, 2021 hCDKL5 refers to the human cyclin-dependent kinase like 5 that is primarily expressed in the brain. Mutations in its coding sequence are often causative of hCDKL5 deficiency disorder, a devastating neurodevelopmental disorder currently lacking a cure ...
Marco Fondi +9 more
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Heterologous Expression of Functional Ptr ToxA [PDF]
Molecular Plant-Microbe Interactions, 2000 Ptr ToxA, a proteinaceous host-selective toxin (HST) produced by the fungus Pyrenophora tritici-repentis, was expressed in Escherichia coli and purified as a polyhistidine-tagged, fusion protein (NC-FP).
Robert P. Tuori +2 more
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Heterologous expression of human transketolase [PDF]
The International Journal of Biochemistry & Cell Biology, 1998 Transketolase belongs to the family of thiamin diphosphate dependent enzymes. The aim of this study was to establish a bacterial expression system for human transketolase in order to investigate the functional characteristics of mammalian transketolases. The level of recombinant human enzyme expressed in Escherichia coli was modest.
Schenk, Gerhard +2 more
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Heterologous Expression of Limulus Rhodopsin [PDF]
Journal of Biological Chemistry, 2003 Invertebrates such as Drosophila or Limulus assemble their visual pigment into the specialized rhabdomeric membranes of photoreceptors where phototransduction occurs. We have investigated the biosynthesis of rhodopsin from the Limulus lateral eye with three cell culture expression systems: mammalian COS1 cells, insect Sf9 cells, and amphibian Xenopus ...
Barry E, Knox +8 more
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Frontiers in Microbiology, 2018 Streptomyces lividans is a suitable host for the heterologous expression of biosynthetic gene clusters (BGCs) from actinomycetes to discover “cryptic” secondary metabolites. To improve the heterologous expression of BGCs, herein we optimized S.
Qinying Peng +11 more
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ENHANCED HETEROLOGOUS EXPRESSION IN E.COLI
Studia Universitatis Babes-Bolyai Chemia, 2019 Apoptotic regulation has been implicated in many human diseases, including cancer, autoimmune disease, inflammation and neuro degradation. Mapping up critical apoptosis regulators is a strategy for the development of new therapies [1, 2].
Katalin NAGY +5 more
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Revista Colombiana de Biotecnología, 2020 Lignocellulose is the main and most abundant component of biomass. Annually, 200 million tons are generated in the world. Colombia has a high production of lignocellulosic residues that can be used in many industrial processes such as bioethanol ...
Natalia Gutierrez Calle +2 more
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Electronic Journal of Biotechnology, 2014 Background: Jatropha curcas is a rich reservoir of pharmaceutically active terpenoids. More than 25 terpenoids have been isolated from this plant, and their activities are anti-bacterial, anti-fungal, anti-cancer, insecticidal, rodenticidal, cytotoxic ...
Lei Wei +4 more
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Microbial Cell Factories, 2021 Background Ganoderma lucidum, a well-known medicinal mushroom, has received wide attention as a promising cell factory for producing bioactive compounds.
Hao You, Bin Sun, Na Li, Jun-Wei Xu
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Microbial Cell Factories, 2017 Background The biosynthesis pathway of benzoxazole compounds caboxamycin and nataxazole have been recently elucidated. Both compounds share one of their precursors, 3-hydroxyanthranilate (two units in the case of nataxazole).
Armando A. Losada +3 more
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