Results 131 to 140 of about 9,435 (185)

Pathogenesis of Tuberculosis: Interplay Between Host Antituberculosis Immunity and Immune Evasion Strategies of Mycobacterium Tuberculosis

MedComm, Volume 7, Issue 8, August 2026.
Mycobacterium tuberculosis–host interactions and infection outcomes. Following initial infection, alveolar macrophages phagocytose the pathogen, prompting the recruitment of innate immune cells including neutrophils, NK cells, and interstitial macrophages.
Xiaojuan Zhang, Ying Liu, Yilin Hou, Hongxia Niu   +3 more
wiley   +1 more source

Engineered Bacterial Membranes as Next‐Generation Platforms for Cancer Immunotherapy

Small Science, Volume 6, Issue 8, August 2026.
Engineered bacterial membrane platforms, including outer membrane vesicles, bacterial ghosts, genetically engineered membranes, and hybrid bacterial–tumor membranes, integrate tumor antigen presentation with intrinsic immune stimulation. These platforms promote dendritic‐cell activation, T‐cell priming, pyroptosis, and synergistic responses with ...
Hafiza Aasia Malik, Urooj Yousaf Virk, Mohamed Salah Attia, Jenny Wilson, Ming Wei   +4 more
wiley   +1 more source

TolC Is Required for a Mixed‐Linkage β‐Glucan (MLG) Biosynthesis: Engineering Bacteria for MLG Overproduction

Microbial Biotechnology, Volume 19, Issue 8, August 2026.
TolC is identified as an essential component of the mixed‐linkage β‐glucan (MLG) biosynthetic machinery in Sinorhizobium meliloti, likely enabling polymer export. Co‐expression of tolC, bgsBA, and pleD* significantly enhances MLG production and enables its synthesis in non‐native bacterial hosts.
L. Ruiz‐Sáez, P. J. Pacheco, J. Peinado, J. Lloret, S. Muñoz, J. Sanjuán, D. Pérez‐Mendoza   +6 more
wiley   +1 more source

A Safe and Effective Bivalent Vaccine Candidate Against Duck Enteritis Virus and Duck‐Origin Novel Goose Parvovirus

Microbial Biotechnology, Volume 19, Issue 8, August 2026.
NGPV VP2 is expressed made DEV as vector and experessed NGPV VP2 could form virus‐like particles. rNGPV VP2‐Cre could facilitate clearance of NGPV and provided strong protection against highly virulent DEV. ABSTRACT Since 2015, duck‐origin novel goose parvovirus (NGPV) has caused severe economic losses to the Chinese duck industry, with no licensed ...
Liu Chen, Jionggang Hua, Weicheng Ye, Cun Zhang, Xinjin Li, Yinchu Zhu, Yuan Fu, Liang He, Suxin Huo, Zongxiao Wang, Zhuanli Wu, Tao Yun   +11 more
wiley   +1 more source

Exploration of Length and Hydrophobicity Requirements for Optimal α‐Amylase Secretion in Bacillus subtilis Based on Rational Design

Microbial Biotechnology, Volume 19, Issue 8, August 2026.
Rational engineering of the B. subtilis α‐amylase signal peptide (SPAmyE) utilizing an in silico modelling approach to design a shorter, but functional SPAmyE. A synthetic SPAmyE with approximately 60% of the original length was generated and facilitated secretion of AmyE to comparable levels as the native SPAmyE.
Dicky A. Pranoto, Danilo Milo, Lorenzo de la Parra Soto, Jolanda Neef, Girbe Buist, Jan Maarten van Dijl   +5 more
wiley   +1 more source

Longitudinal study comparing IgG antibodies induced by heterologous prime-boost COVID-19 vaccine. [PDF]

J Med Virol, 2023
Lin-Wang HT, Damiani LP, Farias EDS, Bajgelman MC, Gun C.   +4 more
europepmc   +1 more source

The Role of CD4 T Cell Repertoire and Immune Memory Mechanisms in Vaccination and Infection Immunity

Immunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT CD4+ T cells orchestrate adaptive immunity against respiratory viruses through functionally distinct subsets, yet the qualitative differences between vaccine‐ and infection‐induced responses remain incompletely understood. This review summarizes current evidence on how CD4+ T cell subsets shape the magnitude, breadth, and durability of ...
Masato Kubo
wiley   +1 more source

Does ChAdOx1-S and BNT162b2 heterologous prime-boost vaccination trigger higher rates of vaccine-related adverse events? [PDF]

IJID Reg, 2023
Haji A, Alkattan A, Mahmoud N, Elkagam E, Hassanein M, Alfaifi A, Al-Tawfiq JA, Alabdulkareem K, Jokhdar H, Radwan N.   +9 more
europepmc   +1 more source

GC B Cells, Tfh Cells, and Influenza bnAbs: Insights for Improving Universal Vaccine Design

Immunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT Antibodies are crucial for providing protection against influenza virus infection; however, protective humoral immunity is limited by antigenic drift and shift. Hence, the discovery of broadly neutralizing antibodies (bnAbs) targeting conserved epitopes on hemagglutinin protein evokes the hope of developing a universal influenza vaccine ...
Takeshi Inoue, Wataru Ise, Tomohiro Kurosaki   +2 more
wiley   +1 more source

Reconfiguring biofortification strategies to transform food systems and address micronutrient deficiency of the 21st century

Journal of Integrative Plant Biology, Volume 68, Issue 8, Page 2511-2547, August 2026.
This review explores how to make staple foods and horticultural crops more nutritious, including how artificial intelligence‐based screening of gene banks helps deploy nutritionally rich germplasm into breeding. Genome editing can help develop crops richer in minerals, vitamins, and health‐promoting compounds, supporting healthier diets and more ...
Rhowell Jr. N. Tiozon, Alisdair R. Fernie, Nese Sreenivasulu   +2 more
wiley   +1 more source