Results 11 to 20 of about 163 (90)

Heterophyllin B enhances the benefits of intermittent fasting in the treatment of metabolic dysfunction‑associated steatotic liver disease via activation of GLP‑1R. [PDF]

open access: yesInt J Mol Med
Intermittent fasting (IF) has shown particularly promising short‑term effects in improving metabolic dysfunction‑associated steatotic liver disease (MASLD), although its long‑term efficacy remains unclear. Heterophyllin B (HP‑B), a cyclopeptide compound derived from Pseudostellaria heterophylla, is known for its potent anti‑inflammatory and ...
Li K, Deng L, Xue L, Yao S.
europepmc   +4 more sources

Muribaculum intestinale-derived 3-hydroxybutyric acid from Heterophyllin B attenuated pulmonary fibrosis through IDO1-mediated ferroptosis

open access: yesPharmacological Research
Pulmonary fibrosis (PF) is a fatal disease with increasing incidence, poor prognosis, and unclear pathogenesis. Our previous research demonstrated the beneficial effects of the natural cyclopeptide Heterophyllin B (HB) in PF.
Ce Chen   +5 more
doaj   +3 more sources

Heterophyllin B alleviates diabetes-induced myocardial injury by regulating MAVS-mediated mitochondrial homeostasis

open access: yesJournal of Nutritional Biochemistry
Diabetic cardiomyopathy (DCM), a major cause of diabetic mortality, lacks effective therapies. This study investigated the cardioprotective role of Heterophyllin B (HET-B), a natural compound and its underlying mechanisms in DCM. Using streptozotocin-induced DCM mice and high glucose (HG)-treated H9C2/neonatal cardiomyocytes, we assessed cardiac ...
Haoran Hu, Ling Zhang
exaly   +3 more sources

Fructus Aurantii Extracts Ameliorate Intestinal Inflammation and Regulate the Intestinal Barrier through Fc Epsilon RI Signaling Pathway

open access: yesJournal of Food Biochemistry, Volume 2023, Issue 1, 2023., 2023
Fructus Aurantii (FA) is the dry and immature fruit of Citrus aurantium L. and its rutaceous cultivars. FA has been widely used to treat digestive system diseases since ancient China, and it promotes gastrointestinal (GI) motility in functional dyspepsia (FD), but its potential therapeutic mechanisms remain unclear.
Sicong Liu   +11 more
wiley   +1 more source

Functional foods with dipeptidyl peptidase‐4 inhibitory potential and management of type 2 diabetes: A review

open access: yesFood Frontiers, Volume 2, Issue 2, Page 153-162, June 2021., 2021
Categories of functional foods with dipeptidyl peptidase‐4 inhibitory effect Abstract The global high prevalence of diabetes mellitus has resulted into the development of several oral hypoglycemic agents. However, these drugs have limited efficacy and harmful side effects, which call for the search for alternatives from natural sources.
Mutiu Kazeem   +4 more
wiley   +1 more source

Comparison of Chemical Compositions in Pseudostellariae Radix from Different Cultivated Fields and Germplasms by NMR-Based Metabolomics

open access: yesMolecules, 2016
Pseudostellariae Radix (PR) is an important traditional Chinese medicine (TCM), which is consumed commonly for its positive health effects. However, the chemical differences of PR from different cultivated fields and germplasms are still unknown.
Yujiao Hua   +8 more
doaj   +1 more source

Isoprenylated Phenolics from Roots of

open access: yesNatural Product Communications, 2017
Thirteen compounds were isolated from Artocarpus heterophyllus , including one new di-isoprenylated stilbene, (±)-artoheterin A ( 1 ), and twelve known isoprenylated phenolics, artocarbene ( 2 ), 3′,5′,2,4-tetrahydroxy-4′-(3-methyl-2-butenyl) stilbene ...
Xiao Xiao Zhai   +5 more
doaj   +1 more source

太子参环肽B(Heterophyllin B, HB)的酶环化反应 [PDF]

open access: yesScience in China Series B-Chemistry (in Chinese), 2005
利用从 Pseudostellaria heterophylla 提取分离的粗酶PH-1, 以链八肽NH 2 -Gly 1 -Gly 2 -Leu-Pro-Pro-Pro-Ile-Phe-COOH (4)为底物成功地进行了太子参环肽B(heterophyllin B (HB))的环化反应, 并利用TLC, HPLC, M, NMR以及同位素标记等手段对反应产物进行了分析和确证.
openaire   +1 more source

Identification and expression analysis of R2R3-MYB transcription factor in Pseudostellaria heterophylla

open access: yesGuangxi Zhiwu
R2R3-MYB transcription factor plays an important role in plant growth and development, stress response, and secondary metabolism. In order to explore the temporal and spatial expression pattern of R2R3-MYB transcription factors in Pseudostellaria ...
HUANG Yishu, HE Hua, ZHOU Tao, PAN Qi, LIU Hongxia, XU Jiao, OU Xiaohong, JIANG Weike*
doaj   +1 more source

Solasodine, Isolated from Solanum Sisymbriifolium Fruits, Has a Potent Anti-Tumor Activity Against Pancreatic Cancer [Retraction]

open access: yesDrug Design, Development and Therapy, 2023
Fan Y, Li Z, Wu L, et al. Drug Des Devel Ther. 2021;15:1509–1519. At the author’s request, we, the Editors and Publisher of Drug Design, Development and Therapy, have retracted the following article.
Fan Y   +8 more
doaj  

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