Antitumor Cyclic Hexapeptides from Rubia Plants: History, Chemistry, and Mechanism (2005–2011) [PDF]
, 2011 Rubiaceae-type cyclopeptides (RAs), cyclic hexapeptides from Rubia plants, have shown potential antitumor activity in vitro and in vivo. Based on the review about plant cyclopeptides (Chem.
Fan, Jun Ting +5 more
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Phytochemical Omics in Medicinal Plants [PDF]
, 2022 Medicinal plants are used to treat diseases and provide health benefits, and their applications are increasing around the world. A huge array of phytochemicals have been identified from medicinal plants, belonging to carotenoids, flavonoids, lignans, and
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太子参环肽B(Heterophyllin B, HB)的酶环化反应 [PDF]
Science in China Series B-Chemistry (in Chinese), 2005 利用从 Pseudostellaria heterophylla 提取分离的粗酶PH-1, 以链八肽NH 2 -Gly 1 -Gly 2 -Leu-Pro-Pro-Pro-Ile-Phe-COOH (4)为底物成功地进行了太子参环肽B(heterophyllin B (HB))的环化反应, 并利用TLC, HPLC, M, NMR以及同位素标记等手段对反应产物进行了分析和确证.
俊 周 +5 more
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Drug Design, Development and Therapy, 2023 Fan Y, Li Z, Wu L, et al. Drug Des Devel Ther. 2021;15:1509–1519. At the author’s request, we, the Editors and Publisher of Drug Design, Development and Therapy, have retracted the following article.
Fan Y +8 more
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Novel Polysaccharide H-1-2 from Pseudostellaria Heterophylla Alleviates Type 2 Diabetes Mellitus [PDF]
, 2018 Background/Aims: To investigate the potential therapeutic effect of novel polysaccharide H-1-2 from pseudostellaria heterophylla against type 2 Diabetes Mellitus (T2DM) and elucidate the underling molecular mechanisms.
Jin-dong Zhao +4 more
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Division of Natural Products Chemistry [PDF]
, 2008 この論文は国立情報学研究所の学術雑誌公開支援事業により電子化されまし
Awale Suresh +2 more
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INTEGRATING CHEMICAL, BIOLOGICAL AND PHYLOGENETIC SPACES OF AFRICAN NATURAL PRODUCTS TO UNDERSTAND THEIR THERAPEUTIC ACTIVITY [PDF]
, 2019 INTEGRATING CHEMICAL, BIOLOGICAL AND PHYLOGENETIC SPACES OF AFRICAN NATURAL PRODUCTS TO UNDERSTAND THEIR THERAPEUTIC ACTIVITY Fatima Magdi Hamza Baldo This research aims to utilise ligand-based target prediction to (i) understand the mechanism of ...
Baldo, Fatima Magdi Hamza
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Magnetic Resonance in ChemistryABSTRACT Heterophyllin B is a natural occurring cyclic peptide with diverse attributed bioactivities. NMR‐based conformational analysis of cyclic peptides often poses a challenge due to limited isotropic solution‐state NMR data. In this study, we combined isotropic and anisotropic NMR observables including
Anton F. Ketzel +5 more
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Integrated transcriptomic and proteomic analysis of exogenous abscisic acid regulation on tuberous root development in Pseudostellaria heterophylla [PDF]
Abscisic acid (ABA) significantly regulates plant growth and development, promoting tuberous root formation in various plants. However, the molecular mechanisms of ABA in the tuberous root development of Pseudostellaria heterophylla are not yet fully ...
Chongmin Wang +4 more
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Systems pharmacology identifies ajugol-mediated NF-κB/caspase-3 inhibition and isoacteoside-driven p62/mTOR-mediated autophagy as key mechanisms of Rehmanniae Radix and its processed form in Alzheimer’s treatment [PDF]
BackgroundAlzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by the deposition of senile plaques, neurofibrillary tangles, and neuronal dysfunction, resulting in severe cognitive and memory decline.
Chenzi Lyu +23 more
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