Results 91 to 100 of about 5,051 (197)

Real‐Time PCR Helicobacter pylori Test in Comparison With Culture and Histology for Helicobacter pylori Detection and Identification of Resistance to Clarithromycin: A Single‐Center Real‐Life Study

open access: yesHelicobacter, Volume 30, Issue 2, March/April 2025.
ABSTRACT Background In our center, RT‐PCR was integrated as a routine method to diagnose Helicobacter pylori due to its higher availability after COVID‐19 pandemics. The objective of this study was to assess the feasibility and performance of systematically performed RT‐PCR for H.
Kateryna Priadko   +6 more
wiley   +1 more source

Decreased susceptibility to vancomycin and other mechanisms of resistance to antibiotics in Staphylococcus epidermidis as a therapeutic problem in hospital treatment

open access: yesScientific Reports, 2023
Multidrug-resistant coagulase-negative staphylococci represent a real therapeutic challenge. The aim of the study was to emphasize the importance of heteroresistance to vancomycin presence in methicillin-resistant strains of S. epidermidis.
Magdalena Szemraj   +2 more
doaj   +1 more source

Circulation of Highly Drug-Resistant Clostridium difficile Ribotypes 027 and 001 in Two Tertiary-Care Hospitals in Mexico [PDF]

open access: yes, 2018
© 2018, Mary Ann Liebert, Inc.OBJECTIVE: To assess drug susceptibility and characterize Clostridium difficile ribotypes in isolates from two tertiary-care hospitals in Mexico.
Adrian Martinez-Melendez, Adrian   +10 more
core   +2 more sources

Methods to Evaluate Colistin Heteroresistance in Acinetobacter baumannii [PDF]

open access: yes, 2019
The nosocomial pathogen Acinetobacter baumannii is a growing threat to public health due to its increasing resistance to antibiotics including the last-line polymyxin, colistin. Heteroresistance to colistin has been described in A. baumannii, wherein a resistant subpopulation of cells coexisting with a majority susceptible subpopulation actively grows ...
Edgar X, Sherman   +2 more
openaire   +2 more sources

Real‐Time Assessment of H. pylori Infection to Guide Molecular Antibiotic Resistance Testing: A Combined Endoscopy‐Gastric Juice Analysis Approach

open access: yesAlimentary Pharmacology &Therapeutics, Volume 61, Issue 3, Page 465-471, February 2025.
Endoscopy combined with intraprocedural gastric juice analysis is highly accurate for Helicobacter pylori detection and, in case of a positive finding, can selectively direct to antibiotic susceptibility testing. Genotypic susceptibility testing using gastric aspirate accurately detects H. pylori resistance to clarithromycin and levofloxacin, with test
Riccardo Vasapolli   +5 more
wiley   +1 more source

Clinical, Microbiological, and Genetic Characteristics of Heteroresistant Vancomycin-Intermediate Staphylococcus aureus Bacteremia in a Teaching Hospital [PDF]

open access: yes, 2014
The emergence of vancomycin intermediate Staphylococcus aureus (VISA) and heterogeneous VISA (hVISA) is of major concern worldwide. Our objective was to investigate the prevalence, phenotypic and molecular features of hVISA strains isolated from ...
de Gregorio, Stella   +9 more
core   +1 more source

Outsmarting Nightmare: Drug Resistance in Acinetobacter baumannii

open access: yesCanadian Journal of Infectious Diseases and Medical Microbiology, Volume 2025, Issue 1, 2025.
Acinetobacter baumannii is a critical nosocomial pathogen recognized by the WHO as a top‐priority threat due to its extensive drug resistance, particularly in carbapenem‐resistant Acinetobacter baumannii (CRAB) strains. According to recent CDC reports, CRAB is one of the most urgent causes of hospital‐acquired infections, driving longer hospital stays,
Annepu Praveen   +5 more
wiley   +1 more source

Impact of heteroresistance on treatment outcomes of people with drug-resistant TB

open access: yesIJTLD Open
BACKGROUND: Poor treatment outcomes among people with drug-resistant TB (DR-TB) are a major concern. Heteroresistance (presence of susceptible and resistant Mycobacterium tuberculosis in the same sample) has been identified in some people with TB, but ...
R. Crowder   +29 more
doaj   +1 more source

Emergence of plasmid-mediated colistin resistance (MCR-1) among Escherichia coli isolated from South African patients [PDF]

open access: yes, 2016
The polymyxin antibiotic colistin is an antibiotic of last resort for the treatment of extensively drug-resistant Gram-negative bacteria, including carbapenemase- producing Enterobacteriaceae.
Brink, Adrian John   +7 more
core   +2 more sources

Revisiting the Metallo‐β‐Lactamase–Mediated Antibiotic Resistance: Exploring Novel Mechanisms and Therapeutic Strategies

open access: yesInternational Journal of Microbiology, Volume 2025, Issue 1, 2025.
β‐Lactam resistance is one of the major health concerns today, primarily due to enzymes called β‐lactamases. Metallo‐β‐lactamases (MβLs) can cleave a wide range of β‐lactam antibiotics, including carbapenems. These enzymes require zinc (Zn) ions to function and can be inhibited by conventional β‐lactamase inhibitors.
Jahanvi Saini   +5 more
wiley   +1 more source

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