Results 61 to 70 of about 5,051 (197)

In vitro antimicrobials activity against endemic Acinetobacter baumannii multiresistant clones [PDF]

, 2010
BACKGROUND: Multidrug-resistant strains of Acinetobacter baumannii have been reported increasingly around the world. The administration of an association of antibiotics has been proposed to create an active combination and to prevent the emergence of ...
Bajuk, Milena, Bombicino, Karina, De Ambrosio, Alejandra, Famiglietti, Ángela, Gutkind, Gabriel Osvaldo, Nastro, Marcela, Radice, Marcela Alejandra, Rodríguez, Carlos Hernán, Spinozzi, Mariela, Vay, Carlos   +9 more
core   +1 more source

Heteroresistance to Cephalosporins and Penicillins in Acinetobacter baumannii [PDF]

Journal of Clinical Microbiology, 2012
ABSTRACT Heteroresistance to antimicrobial agents may affect susceptibility test results and therapeutic success. In this study, we investigated heteroresistance to cephalosporins and penicillins in Acinetobacter baumannii , a major pathogen causing nosocomial infections. Two A. baumannii
Kuei-Hsiang, Hung, Ming-Cheng, Wang, Ay-Huey, Huang, Jing-Jou, Yan, Jiunn-Jong, Wu   +4 more
openaire   +2 more sources

Phenotypic Detection of Hemin-Inducible Trimethoprim-Sulfamethoxazole Heteroresistance in Staphylococcus aureus

Microbiology Spectrum, 2021
Trimethoprim-sulfamethoxazole (SXT) is a valuable second-line antimicrobial agent to treat methicillin-resistant Staphylococcus aureus infections. Discrepancies between various antibiotic susceptibility testing (AST) methods for SXT susceptibility in S ...
Dennis Nurjadi, Quan Chanthalangsy, Elfi Zizmann, Vanessa Stuermer, Maximilian Moll, Sabrina Klein, Sébastien Boutin, Klaus Heeg, Philipp Zanger   +8 more
doaj   +1 more source

ClassTR: Classifying Within-Host Heterogeneity Based on Tandem Repeats with Application to Mycobacterium tuberculosis Infections. [PDF]

, 2015
Genomic tools have revealed genetically diverse pathogens within some hosts. Within-host pathogen diversity, which we refer to as "complex infection", is increasingly recognized as a determinant of treatment outcome for infections like tuberculosis ...
Chindelevitch, L, Cohen, T, Colijn, C, Moodley, P, Wilson, D   +4 more
core   +3 more sources

Heteroresistance to Meropenem in Carbapenem-Susceptible Acinetobacter baumannii [PDF]

Journal of Clinical Microbiology, 2009
ABSTRACT The characteristics of carbapenem heteroresistance were studied in 14 apparently carbapenem-susceptible Acinetobacter baumannii isolates. The MICs for carbapenems were determined, and the isolates were genotyped by pulsed-field gel electrophoresis (PFGE) and sequence typing (ST).
Ikonomidis, A., Neou, E., Gogou, V., Vrioni, G., Tsakris, A., Pournaras, S.   +5 more
openaire   +3 more sources

An in vitro evaluation of the efficacy of tedizolid: implications for the treatment of skin and soft tissue infections [PDF]

, 2018
Skin and soft tissue infections (SSTI) are among the most commonly occurring infections and evidence suggests that these are increasing world-wide.
Aleryan, Muna, Delpech, Pierre, Gemmell, Curtis, Jones, Brian, Lang, Susan   +4 more
core   +2 more sources

Insight into the Mechanisms and Clinical Relevance of Antifungal Heteroresistance

Journal of Fungi
Antifungal resistance poses a critical global health threat, particularly in immuno-compromised patients. Beyond the traditional resistance mechanisms rooted in heritable and stable mutations, a distinct phenomenon known as heteroresistance has been ...
Yanyu Su, Yi Li, Qiaolian Yi, Yingchun Xu, Tianshu Sun, Yingxing Li   +5 more
doaj   +1 more source

Performance of the Genotype MTBDRPlus resistance patternSamara, Russian Federation [PDF]

, 2009
Background. Russia is a high tuberculosis (TB) burden country with a high prevalence of multidrug resistant tuberculosis (MDRTB). Molecular assays for detection of MDRTB on clinical specimens are not widely available in Russia. Results.
Vladyslav Nikolayevskyy, Yanina Balabanova, Tatyana Simak, Nadezhda Malomanova, Ivan Fedorin, Francis Drobniewski, FA Drobniewski, RA Atun, A Telenti, S Ramaswamy, MH Hazbon, M Zhang, P Jureen, T Kocagoz, TJ Brown, D Hillemann, C Piersimoni, P Miotto, D Hillemann, J Makinen, P Miotto, M Barnard, F Drobniewski, OS Toungoussova, A Kruuner, E Tortoli, M Garrigo, MM de Oliveira, VV Nikolayevskyy, D Garcia de Viedma, V Nikolayevsky, MV Afanas'ev, OS Toungoussova, MY Lipin, H Rinder, GC Baldeviano-Vidalon   +35 more
core   +3 more sources

Photodynamic inactivation increases cell death rate on persistent Staphylococcus aureus

Photochemistry and Photobiology, EarlyView.
Persistent bacteria have the ability to survive extended periods of antibiotic stress by entering a metabolically dormant state. This study investigated persistence formation in two S. aureus strains and evaluated the effects of PDI using curcumin. Post‐PDI time‐kill assays conducted after metabolic recovery showed a higher rate of bacterial death ...
Maria Vitória Silva Pereira, Bruna Carolina Corrêa, Vanderlei Salvador Bagnato, Kate Cristina Blanco   +3 more
wiley   +1 more source

A consensus statement on empiric therapy for suspected gram-positive infections in surgical patients [PDF]

, 2015
15Background: Multidrug resistance among gram-positive pathogens in tertiary and other care centers is common. A systematic decision pathway to help select empiric antibiotic therapy for suspected gram-positive postsurgical infections is presented.

core   +1 more source