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Heterotrimeric G proteins

Current Opinion in Cell Biology, 1996
Over the past year, the thrust of work in the field of heterotrimeric G proteins has been primarily in the following areas: first, resolution of their three-dimensional structures by X-ray crystallography; second, elucidation of the effect of lipid modifications on the Galpha and Ggamma subunits; third, understanding the role of the Gbetagamma dimer in
H E, Hamm, A, Gilchrist
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Heterotrimeric G Proteins and Microtubules

2013
Microtubules, major components of the cytoskeleton, play important roles in a variety of cellular functions including mitosis, intracellular transport, and the modulation of cell morphology. Several studies have demonstrated that specific G-protein alpha subunits bind to tubulin with a high affinity (~130 nM) and elicit various functional effects on ...
Witchuda, Saengsawang, Mark M, Rasenick
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Heterotrimeric G Protein Cycle

Science's STKE, 2004
This teaching resource provides two types of insight into the heterotrimeric G protein cycle. The interactive animation shows the basic heterotrimeric G protein cycle and allows the user to then add three different regulators of the cycle, an RGS (regulator of G protein signaling) protein, a GDI (guanine nucleotide dissociation inhibitor) protein, or a
Anita M. Preininger, Heidi E. Hamm
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The Plant Heterotrimeric G-Protein Complex

Annual Review of Plant Biology, 2007
Heterotrimeric G-protein complexes couple extracellular signals via cell surface receptors to downstream enzymes called effectors. Heterotrimeric G-protein complexes, together with their cognate receptors and effectors, operate at the apex of signal transduction.
Brenda R S, Temple, Alan M, Jones
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Heterotrimeric G proteins in heart disease

Cellular Signalling, 1996
Heterotrimeric G proteins couple many types of cell surface receptors to intracellular effectors such as enzymes or ion channels. In the mammalian heart, G protein-mediated signalling pathways are involved in the regulation of contractile force, heart rate, conduction velocity, and relaxation.
P, Schnabel, M, Böhm
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Heterotrimeric G-proteins and development

Biochemical Pharmacology, 1997
Heterotrimeric G-proteins are well-known transducers of signaling from a populous class of heptihelical, membrane receptors to a smaller group of effector molecules that includes adenylylcyclases, cyclic GMP phosphodiesterases, phospholipases (type C beta), and various ion channels.
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