Results 161 to 170 of about 58,740 (306)

Putative binding of <i>Piper betle</i> L. phytochemicals to mannitol pathway enzymes during sporulation of <i>Eimeria tenella</i>. [PDF]

Vet Anim Sci
Wibowo S, Hamid PH, Ristanti R, Nugroho HA, Nashrulloh MM, Nuringtyas TR, Ferdian PR, Amalia RLR, Caro TM, Maulydia NB, Kusumarini S, Wardhana AH, Cahyadi M, Matsubayashi M.   +13 more
europepmc   +1 more source

Targeting the PI3K/Akt Signaling Pathway: A Promising Therapeutic Strategy to Reduce Cancer Mortality and Overcome Chemoresistance

Health Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background and Aims The phosphatidylinositol 3‐kinase (PI3K)/Akt signaling pathway is a central regulator of cellular properties that are essential for cancer progression, including cellular growth, survival, metabolism, and angiogenesis. Dysregulated PI3K/Akt signaling, often caused by genetic alterations in PIK3CA, loss of PTEN, or the ...
Md Mohiuddin
wiley   +1 more source

An <i>HK1</i> pathogenic variant associated with an atypical retinal dystrophy phenotype: a case report and insights from literature. [PDF]

Int J Ophthalmol
Su YY, Qiu KR, Wen F, Zhou XL.
europepmc   +1 more source

Hexokinase Activity in Brain

Journal of Biological Chemistry, 1962
E L, BENNETT, J B, DRORI, D, KRECH, M R, ROSENZWEIG, S, ABRAHAM   +4 more
openaire   +2 more sources

Skeletal Muscle Fibre Type Determines Mitochondrial and Metabolic Responses to Hypoxia and Pulmonary Inflammation in Young Adult Rats

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Chronic obstructive pulmonary disease (COPD) patients often experience skeletal muscle dysfunction that may result from a complex combination of mitochondrial dysfunction, metabolic reprogramming and fibre type transitions. Among other factors, pulmonary inflammation and hypoxia contribute to the COPD‐associated muscle defects ...
Angelos Gavrielatos, Cécile Cottet‐Rousselle, Noé Brocker, Cindy Tellier, Amel Achouri, Alexandre Prola, Hervé Dubouchaud, Clovis Chabert   +7 more
wiley   +1 more source

Hexokinase 2 and Carbohydrate Metabolism: A Multifaceted Metabolic Hub. [PDF]

Genes (Basel)
Maslanka R, Folta J, Lubińska M, Słota Ł, Zadrag-Tecza R.   +4 more
europepmc   +1 more source

The Sleeping Giant: Metabolism and Autophagy in the Generation and Survival of Dormant Polyploid Giant Cancer Cells

MedComm, Volume 7, Issue 10, October 2026.
Polyploid giant cancer cells (PGCCs) arise in response to stress and play a critical role in therapy resistance and tumor dormancy. These cells can evade conventional treatments and later contribute to cancer relapse by generating progeny through nonmitotic, amitotic mechanisms.
Silvia Guil‐Luna, María Teresa Sánchez‐Montero, Alejandra Díaz‐Chacón, Antonio Rodríguez‐Ariza   +3 more
wiley   +1 more source

Hexokinase-3 upregulation and histone H3K18 lactylation mediate murine liver fibrosis induced by Echinococcus multilocularis. [PDF]

PLoS Negl Trop Dis
Miao Y, Shan L, Liu J, Cui W, Yang X, Xiu L, Yang W, Li C, Liu W, Wang Y, Zhang T, Hu W.   +11 more
europepmc   +1 more source

The hexokinase of boar spermatozoa [PDF]

Biochemical Journal, 1968
openaire   +2 more sources

Hippo Pathway–YAP/TAZ Signaling: Molecular Mechanisms, Biological Function, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 10, October 2026.
The Hippo–YAP/TAZ–TEAD pathway integrates mechanical and biochemical cues to govern organ growth, regeneration, cancer, and fibrosis. This review dissects pathway physiology, TEAD structural pharmacology and ligandable pockets, and therapeutic strategies spanning palmitoylation‐pocket inhibitors, PROTAC degraders, and gene/RNA therapies, highlighting ...
Xiaodan Qu, Zhan‐you Wang
wiley   +1 more source