Results 151 to 160 of about 58,740 (306)

Evaluation of the in vitro quality of X‐ray irradiated red cell concentrates processed and stored using di(2‐ethylhexyl) terephthalate plasticized blood bag sets

open access: yesVox Sanguinis, EarlyView.
Abstract Background and Objectives Polyvinyl chloride (PVC) blood bags plasticized with di(2‐ethylhexyl) phthalate (DEHP) have long been the standard for red blood cell (RBC) storage. Due to safety concerns, alternatives like di(2‐ethylhexyl) terephthalate (DEHT), in combination with next‐generation additive solutions like phosphate‐adenine‐glucose ...
Carly Olafson   +3 more
wiley   +1 more source

The phosphorylation of some analogues of fructose by yeast hexokinase [PDF]

open access: yes, 2018
Since Meyerhof separated hexokinase in a purified form from bakers’ yeast a great deal of information on the properties of this enzyme has bene obtained by numerous workers.
Burt, James R.
core  

Continuous agitation induces aggregate formation in cold‐stored platelets during extended storage in platelet additive solution

open access: yesVox Sanguinis, EarlyView.
Abstract Background and Objectives Reduced metabolic activity of cold‐stored platelets (CSPs) has led to the assumption that agitation is not required during cold storage. However, guidelines from the Food and Drug Administration state that agitation is ‘optional’ and there is a degree of international variability described in the literature.
Janhavi Mahajan   +5 more
wiley   +1 more source

Placental mitochondrial metabolic adaptation maintains cellular energy balance in pregnancy complicated by gestational hypoxia

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Placental mitochondrial adaptation to gestational hypoxia. Hypoxic pregnancy in sheep increases placental insulin like growth factor 2 (IGF2) signalling (1), which is associated with a shift in capacity away from β‐oxidation (2) and complex I‐mediated respiration (3), while maintaining total oxidative phosphorylation capacity (4).
Wen Tong   +18 more
wiley   +1 more source

Excessive training does not induce mitochondrial dysfunction or impair insulin signalling within skeletal muscle

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Three weeks of overtraining in trained endurance athletes reduced exercise performance without impairing glucose tolerance. In skeletal muscle, overtraining was associated with increased expression of lipid metabolism‐related proteins, enhanced mitochondrial biogenesis and preserved insulin signalling, despite elevated oxidative ...
Geneviève J. DesOrmeaux   +7 more
wiley   +1 more source

Regulation of energy metabolism in tumor cells : the role of hexokinase

open access: yes, 1990
Changes in glucose metabolism are among the most universal andfundamental metabolic alterations observed in cancer cells. Hexokinase isthe initial regulatory enzyme which controls the rate of glucose entranceinto the glycolytic pathway.
Kabir, Firoz,
core  

Glucose and fructose contributions to exogenous carbohydrate oxidation and performance at moderate altitude

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Co‐ingesting fructose with glucose increases exogenous carbohydrate oxidation at sea level, but its effect at altitude is unclear. This study compared glucose–fructose (GLU–FRU), glucose alone (GLU) and placebo during 120 min of running at 70% V̇O2max${{\dot{V}}_{{{{\mathrm{O}}}_2}{\mathrm{max}}}}$ at 2500 m in eight males.
Nicola C. Arjomandkhah   +7 more
wiley   +1 more source

Assessment of Biochemical Analytes Stability: The Role of Centrifugation and Storage Conditions in the Preanalytical Phase

open access: yesAnalytical Science Advances, Volume 7, Issue 2, December 2026.
Assessing the impact of different preanalytical factors on biochemical analyte concentrations helps to control emerging risks associated with sample handling. In this study, we provide evidence that the stability of serum biochemical analytes was strongly dependent on both storage temperature and duration.
Zivile Jacike   +8 more
wiley   +1 more source

Metabolic Flux Analysis Reveals Cell Line‐Specific Rewiring in CHO Cells Following TCA Cycle Intermediate Feeding for Bioprocess pH Control

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 10, Page 2713-2728, October 2026.
ABSTRACT Chinese hamster ovary (CHO) cells are the leading host for recombinant therapeutic protein production in the biopharma industry. In this study, we investigated how feeding acidic forms of tricarboxylic acid (TCA) cycle intermediates—malic acid, succinic acid, and α‐ketoglutaric acid—affects cell culture performance and metabolism in two ...
Sarah A. Sacco   +8 more
wiley   +1 more source

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