Results 131 to 140 of about 83,479 (285)
ABSTRACT Aims The revised Lancet Commission framework prioritizes excess adiposity over body mass index (BMI) alone for diagnosing obesity, emphasizing population‐specific body fat assessments. However, body fat percentage (BFP) thresholds reflecting adiposity‐defined obesity remain limited, particularly by sex and age in Asian populations.
Han Na Jung +8 more
wiley +1 more source
Coexisting Asthma and Diabetes Are Associated With Adverse Metabolic and Inflammatory Profiles
ABSTRACT Aims Asthma and diabetes frequently co‐occur and share metabolic and inflammatory features, yet the cardiometabolic profile associated with their coexistence is not well defined. We examined differences in cardiometabolic and inflammatory biomarkers by joint asthma–diabetes status in U.S.
Sixtus Aguree +4 more
wiley +1 more source
Altered metabolism represents a fundamental difference between cancer cells and normal cells. Cancer cells have a unique ability to reprogram their metabolism by deviating their reliance from primarily oxidative phosphorylation (OXPHOS) to glycolysis, in
Erna Mitaishvili +6 more
doaj +1 more source
Flagellar Radial Spoke Protein 2 Is a Calmodulin Binding Protein Required for Motility in \u3cem\u3eChlamydomonas reinhardtii\u3c/em\u3e [PDF]
Genetic and morphological studies have revealed that the radial spokes regulate ciliary and flagellar bending. Functional and biochemical analysis and the discovery of calmodulin in the radial spokes suggest that the regulatory mechanism involves control
Sale, Winfield S. +2 more
core +1 more source
ABSTRACT Aims To evaluate the effects of premeal versus postmeal metformin administration on postmeal glycemic control in individuals with type 2 diabetes mellitus receiving metformin monotherapy. Methods All participants were randomly assigned to receive immediate‐release metformin either 30–60 min before or immediately after meal for 4 weeks, and ...
Issaree Rattarasarn +5 more
wiley +1 more source
In Huh7 cells, HIF‐1α is essential as it maintains the expression of proteins involved in glycolysis and steroid/cholesterol biosynthesis both under normoxia and hypoxia. On the other hand, in HeLa cells, these pathways are induced by HIF‐1α only under hypoxia.
Ioanna‐Maria Gkotinakou +6 more
wiley +1 more source
The ribosome‐associated complex regulates cytosolic translation upon mitoprotein‐induced stress
Defects in mitochondrial protein import trigger a stress response. The contribution of translation regulation to such a response is only partially understood. We demonstrate that the deletion of mitochondrial surface proteins (TOM70/TOM71) leads to defects in mitochondrial biogenesis and slow growth.
Jiaxin Qian +7 more
wiley +1 more source
Hexokinase, Malate Dehydrogenase, Fluorescent Esterase and Malic Enzyme Polymorphisms in the Cocoa Pod Borer, Conopomorpha cramerella (Snellen) [PDF]
Cocoa pod borers collected in the field from Tawau, Sabah and from Sua Betong, Negeri Sembilan and rambutan fruit borers collected from Puchong and the campus of Universiti Pertanian Malaysia (UPM) in Serdang, Selangor, Malaysia were analysed by ...
Gan, Yik Yuen +3 more
core
VA molecules alter VDAC1 gating by increasing anion flow and reducing cation permeability. In cancer cells, which rely on ER‐mitochondria Ca2+ transfer and overexpress VDAC1, this imbalance triggers bioenergetic stress, ROS buildup, and mitochondrial collapse, leading to cell death.
Stefano Conti‐Nibali +6 more
wiley +1 more source

