Results 121 to 130 of about 58,740 (306)
Artesunate Alleviates Apical Periodontitis Macrophage Glycolysis Via Jak2/Stat3 Pathway
International Dental JournalAim or purpose: Macrophage (Mφ) glycolysis has emerged as a critical regulator of apical periodontitis (AP) progression. Based on this glycolytic mechanism, our study investigates the therapeutic potential and underlying mechanisms of artesunate (ART) in
Yani He, Liu Han, Wang Zecheng
doaj +1 more source
Integrative Zoology, EarlyView.High altitudes are challenging for the animals that inhabit these environments. The Xizang plateau frog (Nanorana parkeri) survives in high‐altitude environments through a synergistic strategy of metabolic remodeling and protein expression adjustment to optimize energy efficiency and enhance cellular protection.
Xuejing Zhang +6 more
wiley +1 more source
Monomeric structures of hexokinase I [PDF]
, 1999 Hexokinase I, the pacemaker of glycolysis in brain tissue, is composed of two structurally similar halves connected by an [Alpha]-helix. The enzyme dimerizes at elevated protein concentrations in solution and in crystal structures; however, almost all ...
Kirby, Christina Ann
core
Australian Veterinary Journal, EarlyView.Blood glucose is a key physiological indicator in sea turtles, but its measurement in field settings can be challenging. Portable point‐of‐care (POC) glucometers offer practicality, yet their agreement with reference laboratory methods has not been established for juvenile green sea turtles (Chelonia mydas) from the Southwestern Atlantic.
YAA Pérez +16 more
wiley +1 more source
Molecular Plant-Microbe InteractionsThe potato cyst nematode (Globodera rostochiensis) is an obligate root pathogen of potatoes. G. rostochiensis encodes several highly expanded effector gene families, including the Gr4D06 family; however, little is known about the function of this ...
Shiyan Chen +6 more
doaj +1 more source
, 2014 Hexokinase catalyses the first step in the metabolism of glucose, but has also been proposed to be involved in sugar sensing and signalling in both yeasts and plants.
Cakir, Birsen
core +1 more source
Targeting hexokinase 2 to induce breast cancer cell senescence
British Journal of Pharmacology, EarlyView.Background and Purpose Hexokinase 2 (HK2) is a key enzyme linked to high tumour cell proliferation. Its inhibitors such as 3‐bromopyruvic acid (3‐BP) induce cancer cell death, highlighting HK2 modulation as potential anti‐cancer treatment. However, standard chemotherapies often cause the emergence of senescent cancer cells, which goes along with cell ...
Helmut Bischof +8 more
wiley +1 more source
Studies on hexokinase: 3. An activator of hexokinase in muscle extracts [PDF]
Biochemical Journal, 1951 H, WEIL-MALHERBE, A D, BONE
openaire +2 more sources
Cancer Science, EarlyView.tRNA‐derived small RNAs (tsRNAs) function in digestive cancers across three scales: intracellular translational and metabolic control, extracellular vesicle–mediated immune remodeling, and systemic and host–microbe communication. This review organizes these mechanisms by evidence strength, from well‐established intracellular roles to emerging ...
Wang Xitan, Li Han
wiley +1 more source
From hepatic to hematopoietic: LRH‐1's expanding cellular repertoire to the immune system
The FEBS Journal, EarlyView.The nuclear receptor LRH‐1 is a well‐characterized regulator of endodermal tissue. Yet, increasing evidence indicates that LRH‐1, although expressed at low levels, is also a critical regulator of the hematopoietic system. LRH‐1 regulates the immune system by contributing to immune cell‐specific functions.
Lukas Meisinger +3 more
wiley +1 more source