Results 101 to 110 of about 59,802 (286)

Is hexokinase present in the basal lateral membranes of rat kidney proximal tubular epithelial cells?

open access: yes, 1978
The possible presence of hexokinase in basal lateral membranes from rat kidney proximal tubules was investigated. Basal lateral membranes were obtained from homogenates of rat kidney cortex by differential centrifugation and free flow electrophoresis ...
Kleinzeller, A.   +3 more
core   +1 more source

OXCT1‐driven succinylation of PSMG3 stabilizes the proteasome to facilitate picornavirus replication

open access: yesiMetaOmics, EarlyView.
Upon entering the pig, foot‐and‐mouth disease virus (FMDV) regulates host glycolysis and the citrate cycle by modulating the expression of metabolic enzymes, resulting in changes in post‐translational modifications (PTMs) including succinylation, lactylation, crotonylation, acetylation, and phosphorylation.
Huisheng Liu   +9 more
wiley   +1 more source

Insulin does not change the intracellular distribution of hexokinase in rat heart

open access: yes, 1998
Preliminary evidence has suggested that hexokinase in rat heart changes its kinetic properties in response to insulin through translocation to the outer mitochondrial membrane.
Guthrie, Patrick H.   +9 more
core   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

open access: yesiNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong   +5 more
wiley   +1 more source

Hexokinase and Glucokinases Are Essential for Fitness and Virulence in the Pathogenic Yeast Candida albicans

open access: yesFrontiers in Microbiology, 2019
The pathogenic yeast Candida albicans is both a powerful commensal and a pathogen of humans that can infect wide range of organs and body sites. Metabolic flexibility promotes infection and commensal colonization by this opportunistic pathogen.
Romain Laurian   +6 more
doaj   +1 more source

Basophilic Stippling Unmasks Pyrimidine 5′‐Nucleotidase Deficiency in a G6PD‐Deficient Patient

open access: yes
American Journal of Hematology, EarlyView.
Victor Bobée   +4 more
wiley   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

open access: yesiNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid   +4 more
wiley   +1 more source

Substrate specificity of glucokinase and fructokinase of several conifer species

open access: yesActa Societatis Botanicorum Poloniae, 2014
Annual plant species were found to have several distinct classes of hexokinases which are specific for different hexoses, such as glucose, fructose and mannose.
Fritz Bergmanni, Leon Mejnartowicz
doaj   +1 more source

Expression of a PTS2-truncated hexokinase produces glucose toxicity in Leishmania donovani

open access: yes, 2010
Compartmentalization of glycolytic enzymes in glycosomes is vital in trypanosomatid parasites. Retention of these enzymes in the cytosol induces sugar toxicity and accumulation of intermediate metabolites, notably the hexokinase product glucose-6 ...
Gupta, Chhitar M.   +9 more
core   +1 more source

Assessment of Glucose Metabolism in Vivo in the Human Frontal Lobe Using Interleaved 1H and 13C MRS at 7T

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background 13C magnetic resonance spectroscopy (MRS), combined with 13C‐labeled substrate infusion, offers a nonionizing, minimally invasive method for assessing fluxes through the main cerebral energy metabolism pathways. However, its human application at 7T has not been fully established, especially within the frontal lobe, where alterations
Ying Xiao   +14 more
wiley   +1 more source

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