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Regulation of Hexokinase in Cultured Gliomas

Neurosurgery, 1985
Positron emission computed tomographic (PECT) scanning studies have demonstrated that high grade gliomas exhibit increased 2-[18F]fluoro-2-deoxyglucose (18FDG) uptake compared to cerebral white matter and low grade gliomas. Hexokinase catalyzes the phosphorylation of glucose, as well as 18FDG and 2-deoxyglucose (2DG), thereby "trapping" these slowly ...
J F, Graham   +3 more
openaire   +2 more sources

Thermodynamics of hexokinase catalyzed reactions

Biophysical Chemistry, 1975
Abstract The enthalpies of the hexokinase -catalyzed phosphorylation or glucose, mannose, and fructose by ATP to the respective hexose 6-phosphates have been measured calorimetrically in TRIS/TRIS HCl buffer at 25.0, 28.5, and 32.0°C. The effects on the measured enthalpy of the glucose/ hexokinase reaction due to variation of pH (over the range 6.7
openaire   +2 more sources

[Hexokinase in Alzheimer's disease].

Medicina (Florence, Italy), 1990
Decreased hexokinase activity has been reported in brain, fibroblast, leukocytes and microvessels of patients with Alzheimer's disease. In this paper the results of an investigation on hexokinase activity in an Italian large pedigree are reported. The activity was comparable with that of the normal controls.
Mortilla M, SORBI, SANDRO
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The discovery of hexokinase

Trends in Biochemical Sciences, 1985
15 Burnell, J. N. and Hatch, M. D. (1983) BIO- chem. Biophys. Res. Commun. 111,288-293 16 Bumell, J. N. and Hatch, M. D. Arch. BIO- chem. Biophys. (in press) 17 Ashton, A. R. and Hatch, M. D. (1983) BIO- chem. Biophys. Res. Commun. 115, 53--60 18 Ashton, A. R., Burnell, J. N. and Hatch, M. D. (1984) Arch. Biochem. Biophys. 230, 492-503 19 Bumell, J. N.
openaire   +1 more source

Microbial regulation of hexokinase 2 links mitochondrial metabolism and cell death in colitis

Cell Metabolism, 2021
Stefan Krautwald   +2 more
exaly  

Advances in the Study of Hexokinase 2 (HK2) Inhibitors

Anti-Cancer Agents in Medicinal Chemistry, 2023
Chunhong Dong
exaly  

Hexokinase

1997
Dietmar Schomburg, Dörte Stephan
openaire   +1 more source

Hexokinase in cultured gliomas

Neurosurgery, 1986
C W, van Veelen   +3 more
openaire   +2 more sources

Hexokinase 1 cellular localization regulates the metabolic fate of glucose

Molecular Cell, 2022
Navdeep Chandel   +2 more
exaly  

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