Results 91 to 100 of about 810 (162)

The CD4+ T-cell response to adenovirus is focused against conserved residues within the hexon protein

, 2007
Adenovirus is a significant pathogen in immunocompromised patients and is widely utilized as a gene delivery vector, so a detailed understanding of the human immune response to adenovirus infection is critical.
Mautner, Vivien, Moss, Paul; id_orcid, Lee, Steven, Crompton, LJ, Milligan, Donald, Onion, David   +5 more
core   +1 more source

ROLE OF RELATIVE CODON USAGE (RSCU) ON INFECTIVITY AND VIRULENCE OF FOWL ADENOVIRUS ISOLATED FROM INFECTED IRAQI POULTRY

The Iraqi Journal of Agricultural science
This study was aimed to investigate the role of codon usage on infectivity and virulence of fowl adenovirus. The PCR amplicon sequence revealed that loop1 has a hypervariable region and is adjacent to loop2 on Hexon A segment, while Hexon B segment has ...
Aya .R. Abdulla, Rebah .N. Jabbar, Aida .B. Allawe   +2 more
doaj   +1 more source

Nucleotide and amino acid position of the HVRs1-4 regions in the examined fragment of Loop L1 hexon gene of adenovirus strains classified to different types.

, 2018
Nucleotide and amino acid position of the HVRs1-4 regions in the examined fragment of Loop L1 hexon gene of adenovirus strains classified to different types.
Jowita Samanta Niczyporuk (5678207)
core   +1 more source

A novel adenovirus of Western lowland gorillas (Gorilla gorilla gorilla)

Virology Journal, 2010
Adenoviruses (AdV) broadly infect vertebrate hosts including a variety of primates. We identified a novel AdV in the feces of captive gorillas by isolation in cell culture, electron microscopy and PCR.
Ludwig Carsten, Head Josephine, Robbins Martha M, Boesch Christophe, Scuda Nelly, Leendertz Fabian H, Wevers Diana, Kühn Joachim, Ehlers Bernhard   +8 more
doaj   +1 more source

Classification of fowl adenoviruses by use of phylogenetic analysis and high-resolution melting-curve analysis of the hexon L1 gene region

Journal of Virological Methods, 2010
A total of 44 fowl adenovirus (FAdV) samples from 6 European countries, Pakistan, India, Kuwait, Mexico, Peru and Ecuador were used in this study and the phylogenetic analyses based on the loop 1 (L1) region of hexon gene were performed. For comparison, available hexon sequences of representatives of different FAdV species were also used.
MAREK, Ana, Guenes, AYŞE, SCHULZ, Evelyn, HESS, Michael   +3 more
openaire   +3 more sources

Evaluation of qPCR for the Selective Detection of Enteric Adenovirus Followed by Sequence-Based Genetic Characterization of F Strains Circulating in Brazil

Applied Microbiology
Human adenovirus (HAdV) F40/41 is an important pathogen in pediatric acute gastroenteritis cases. However, the diversity of study designs and diagnostic methods often leads to misinterpretations of their impact.
Lilian Gonçalves do Nascimento, Sylvia Kahwage Sarmento, Reinaldo Röpke Junior, Tulio Machado Fumian   +3 more
doaj   +1 more source

Hexon and fiber gene changes in an attenuated fowl adenovirus isolate from Malaysia in embryonated chicken eggs and its infectivity in chickens [PDF]

, 2018
Fowl adenovirus (FAdV) is distributed worldwide and causes economic losses in the poultry industry. The objectives of this study were to determine the hexon and fiber gene changes in an attenuated FAdV isolate from Malaysia in specific pathogen-free ...
Mohamed Sohaimi, Norfitriah, Omar, Abdul Rahman, Bejo, Mohd Hair, Ideris, Aini, Mat Isa, Nurulfiza   +4 more
core   +1 more source

Genomic Epidemiological Characteristics of Enteric Adenovirus F40 and F41 in Yantai, China, from 2022 to 2023

Viruses
This study aims to investigate the genomic epidemiological characteristics of enteric adenovirus types F40 and F41 circulating in Yantai from August 2022 to August 2023, with a focus on genetic diversity, recombination events, and their potential ...
Peihua Niu, Zhenlu Sun, Yu Zhang, Dapeng Zhang, Yiming Zhao, Yi Zhang, Ping Cheng, Qiao Gao, Yu Li, Lili Zhao, Jie Yan, Hongmei Zheng, Xuejun Ma, Ji Wang   +13 more
doaj   +1 more source

Substitution of Hexon Hypervariable Region 5 of Adenovirus Serotype 5 Abrogates Blood Factor Binding and Limits Gene Transfer to Liver

Molecular Therapy, 2008
Liver tropism potentially leading to massive hepatocyte transduction and hepatotoxicity still represents a major drawback to adenovirus (Ad)-based gene therapy. We previously demonstrated that substitution of the hexon hypervariable region 5 (HVR5), the most abundant capsid protein, constituted a valuable platform for efficient Ad retargeting.
Vigant, Frédéric, Descamps, Delphyne, Jullienne, Betsy, Esselin, Stéphanie, Connault, Elisabeth, Opolon, Paule, Tordjmann, Thierry, Vigne, Emmanuelle, Perricaudet, Michel, Benihoud, Karim   +9 more
openaire   +4 more sources

Nucleotide sequence variation in the hexon gene of human adenovirus type 8 and 37 strains from epidemic keratoconjunctivitis patients in Japan

Journal of General Virology, 2009
Human adenovirus type 8 (HAdV-8) and 37 (HAdV-37) cause epidemic keratoconjunctivitis (EKC) associated with community-acquired and nosocomial infections. The nucleotide sequences of the entire hexon and fiber genes of eight HAdV-8 and 26 HAdV-37 strains were analysed and the transition mutations in each gene were compared among strains.
Hisatoshi, Kaneko, Hiroaki, Ishiko, Takeshi, Ohguchi, Yoshitsugu, Tagawa, Koki, Aoki, Tatsuo, Suzutani, Shigeaki, Ohno   +6 more
openaire   +2 more sources