Results 111 to 120 of about 810 (162)

Phylogenetic tree of 198 amino acid residues based on L1 loop hexon gene shown the passaged FAdV isolates in CEL cells (shaded in dark gray) were classified under group E species (shaded in light gray).

open access: yes, 2019
Phylogenetic tree of 198 amino acid residues based on L1 loop hexon gene shown the passaged FAdV isolates in CEL cells (shaded in dark gray) were classified under group E species (shaded in light gray).
Norfitriah Mohamed Sohaimi (8207598)   +4 more
core   +1 more source

Structural insights into the interaction between adenovirus C5 hexon and human lactoferrin

open access: yes
JVIVolume 98, Number 319 March 2024 ABSTRACT INTRODUCTION RESULTS DISCUSSION MATERIALS AND METHODS ACKNOWLEDGMENTS SUPPLEMENTAL MATERIAL REFERENCES Information & Contributors Metrics & Citations References Figures and ...
Zoll, Sebastian,   +23 more
core   +1 more source

Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: effect of mutagenesis on FX interactions and gene transfer

open access: yes, 2009
Recent studies have demonstrated the importance of coagulation factor X (FX) in adenovirus (Ad) serotype 5–mediated liver transduction in vivo. FX binds to the adenovirus hexon hypervariable regions (HVRs).
Barouch, Dan   +26 more
core   +1 more source

Comparative analysis of adenovirus hexon gen region of different species

open access: yes, 2019
AdV'lar, insanlarda ve hayvanlarda enfeksiyonlara neden olabilmektedir. Adenoviridae ailesinde bulunan ve tez çalışmamızda moleküler analizi yapılan insan, sığır ve koyun AdV'ları Mastadenovirus genusunda yer almaktadır.
Baştuğ, Aliye
core  

Ad5:Ad48 hexon hypervariable region substitutions lead to toxicity and increased inflammatory responses following intravenous delivery

open access: yes, 2012
The development of adenoviral vectors for intravascular (i.v.) delivery will require improvements to their in vivo safety and efficacy. The hypervariable regions (HVRs) of the Ad5 hexon are a target for neutralizing antibodies, but also interact with ...
Coughlan, Lynda   +21 more
core   +1 more source

Fiber2 and hexon genes are closely associated with the virulence of the emerging and highly pathogenic fowl adenovirus 4

open access: yes, 2019
Since May 2015, outbreaks of hydropericardium-hepatitis syndrome (HHS) caused by fowl adenovirus 4 (FAdV-4) with a novel genotype have been reported in China, causing significant economic losses to the poultry industry.
Hailong Wang (21678)   +9 more
core   +1 more source

Transductional retargeting of human adenovirus type 5 to ανβ6 integrin for cancer gene therapy

open access: yes, 2009
PhDA key impediment to successful cancer therapy with adenoviral vectors is the inefficient transduction of malignant tissue in vivo. Compounding this problem is the lack of cancer-specific targets, coupled with a shortage of corresponding high ...
Coughlan, Lynda
core  

ApoE gene therapy to treat hyperlipidemia and atherosclerosis

open access: yes, 2006
Atherosclerosis is the leading cause of death in industrialized countries and is becoming an increasingly worldwide risk to health. Apolipoprotein E (ApoE) is a blood circulating protein with pleiotropic atheroprotective properties that has emerged as a ...
Owen, JS   +3 more
core  

High-efficiency gene transfer by adenovirus coupled to DNA-polylysine complexes [PDF]

open access: yes, 1992
Agarwal, Santosh   +7 more
core   +1 more source

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