Results 41 to 50 of about 5,116,032 (159)

Nanoparticles and Glycosaminoglycans: Progress and Applications for Cancer Therapy

open access: yesProteoglycan Research, Volume 3, Issue 1, January-March 2025.
ABSTRACT Glycosaminoglycans (GAGs) play essential roles in biological processes such as cell signaling and extracellular matrix assembly. Alterations in the structure of GAGs have been implicated in cancer pathogenesis, demonstrating their potential as biomarkers for cancer diagnosis and progression, as well as targets for pharmacological interventions.
Pietro Milesi   +4 more
wiley   +1 more source

A Novel Lineage of Endosymbiotic Actinomycetales: Genome Reduction and Acquisition of New Functions in Bifidobacteriaceae Associated With Termite Gut Flagellates

open access: yesEnvironmental Microbiology, Volume 27, Issue 1, January 2025.
We have characterised several novel genera of Bifidobacteriaceae that colonise the cytoplasm of cellulolytic flagellates. Horizontal gene transfer played an important role in their adaptation to the intracellular environment. However, progressive genome erosion led to the loss of biosynthetic capacities that formed the basis of an originally ...
Joana Kästle Silva   +4 more
wiley   +1 more source

Exploring the chemical composition and biological effects of four Salvia hybrids: an innovative perspective on functional yields

open access: yeseFood, Volume 5, Issue 5, October 2024.
It can be concluded that, genus Salvia, as one of the well‐known and phytochemically rich genera of family Lamiaceae, served here as a source of four hybrids which were evaluated as a potential source of biologically important metabolites Abstract Genus Salvia is considered one of the largest genera of family Lamiaceae with many recorded species and ...
Nilofar   +9 more
wiley   +1 more source

Heparin and heparan sulfate—The essence of sequence

open access: yesProteoglycan Research, Volume 2, Issue 4, October-December 2024.
Abstract Heparin, discovered as an anticoagulant more than 100 years ago, is composed of the same structural units as heparan sulfate, and their biosynthesis in the Golgi compartment is carried out by the same families of enzymes. However, while heparin is restricted to mast cells, heparan sulfate is widely distributed and is found at the cell surface ...
Lena Kjellén, Ulf Lindahl
wiley   +1 more source

Glycolanguage of the oral microbiota

open access: yesMolecular Oral Microbiology, Volume 39, Issue 5, Page 291-320, October 2024.
Oral bacteria speak a sophisticated glycolanguage transmitted through versatile glycoinfrastructure, carbohydrate‐active enzymes, and lectins, which contributes decisively to their success in the oral habitat. Deciphering this glycolanguage opens new avenues for novel antibacterials to treat oral diseases. Abstract The oral cavity harbors a diverse and
Fiona F. Hager‐Mair   +2 more
wiley   +1 more source

Ion Mobility Mass Spectrometry‐Based Disaccharide Analysis of Glycosaminoglycans

open access: yesChemistry – A European Journal, Volume 30, Issue 35, June 20, 2024.
Glycosaminoglycans (GAGs) are vital polysaccharides with complex structures. Disaccharide analysis, involving enzymatic depolymerization and liquid chromatography, is commonly used for their analysis. Here, direct infusion nESI ion mobility‐mass spectrometry (IM‐MS) is used to reduce measurement time from hours to minutes.
Lukasz Polewski   +6 more
wiley   +1 more source

The crucial evaluation indexes and relative measurement methods of edible value for fresh fruits and vegetables: A review

open access: yesFuture Postharvest and Food, Volume 1, Issue 2, Page 222-236, June 2024.
Abstract Fresh fruits and vegetables (F&V), with their attractive sensory, flavors, and nutrients, occupy a highly valuable part of people's daily diet. Plenty of postharvest studies have focused on the effects of preservation techniques on the edible quality and nutrients of F&V.
Yiqin Zhang   +8 more
wiley   +1 more source

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