Results 41 to 50 of about 5,116,032 (159)
Nanoparticles and Glycosaminoglycans: Progress and Applications for Cancer Therapy
ABSTRACT Glycosaminoglycans (GAGs) play essential roles in biological processes such as cell signaling and extracellular matrix assembly. Alterations in the structure of GAGs have been implicated in cancer pathogenesis, demonstrating their potential as biomarkers for cancer diagnosis and progression, as well as targets for pharmacological interventions.
Pietro Milesi +4 more
wiley +1 more source
We have characterised several novel genera of Bifidobacteriaceae that colonise the cytoplasm of cellulolytic flagellates. Horizontal gene transfer played an important role in their adaptation to the intracellular environment. However, progressive genome erosion led to the loss of biosynthetic capacities that formed the basis of an originally ...
Joana Kästle Silva +4 more
wiley +1 more source
It can be concluded that, genus Salvia, as one of the well‐known and phytochemically rich genera of family Lamiaceae, served here as a source of four hybrids which were evaluated as a potential source of biologically important metabolites Abstract Genus Salvia is considered one of the largest genera of family Lamiaceae with many recorded species and ...
Nilofar +9 more
wiley +1 more source
Heparin and heparan sulfate—The essence of sequence
Abstract Heparin, discovered as an anticoagulant more than 100 years ago, is composed of the same structural units as heparan sulfate, and their biosynthesis in the Golgi compartment is carried out by the same families of enzymes. However, while heparin is restricted to mast cells, heparan sulfate is widely distributed and is found at the cell surface ...
Lena Kjellén, Ulf Lindahl
wiley +1 more source
Glycolanguage of the oral microbiota
Oral bacteria speak a sophisticated glycolanguage transmitted through versatile glycoinfrastructure, carbohydrate‐active enzymes, and lectins, which contributes decisively to their success in the oral habitat. Deciphering this glycolanguage opens new avenues for novel antibacterials to treat oral diseases. Abstract The oral cavity harbors a diverse and
Fiona F. Hager‐Mair +2 more
wiley +1 more source
Ion Mobility Mass Spectrometry‐Based Disaccharide Analysis of Glycosaminoglycans
Glycosaminoglycans (GAGs) are vital polysaccharides with complex structures. Disaccharide analysis, involving enzymatic depolymerization and liquid chromatography, is commonly used for their analysis. Here, direct infusion nESI ion mobility‐mass spectrometry (IM‐MS) is used to reduce measurement time from hours to minutes.
Lukasz Polewski +6 more
wiley +1 more source
Abstract Fresh fruits and vegetables (F&V), with their attractive sensory, flavors, and nutrients, occupy a highly valuable part of people's daily diet. Plenty of postharvest studies have focused on the effects of preservation techniques on the edible quality and nutrients of F&V.
Yiqin Zhang +8 more
wiley +1 more source
A Major Common Trisulfated Hexasaccharide Core Sequence, Hexuronic Acid(2-Sulfate)-Glucosamine(N-Sulfate)-Iduronic Acid-N-Acetylglucosamine-Glucuronic Acid-Glucosamine(N-Sulfate), Isolated from the Low Sulfated Irregular Region of Porcine Intestinal Heparin [PDF]
Shuhei Yamada +4 more
openalex +1 more source
The Occurrence of Three Isoforms of Heparan Sulfate 6-O-Sulfotransferase Having Different Specificities for Hexuronic Acid Adjacent to the TargetedN-Sulfoglucosamine [PDF]
Hiroko Habuchi +6 more
openalex +1 more source

