Results 141 to 150 of about 32,390 (296)

Myocardial Proteome in Human Heart Failure With Preserved Ejection Fraction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Heart failure with preserved ejection fraction (HFpEF) constitutes more than half of all HF but has few effective therapies. Recent human myocardial transcriptomics and metabolomics have identified major differences between HFpEF and controls.
Vivek P. Jani, Edwin J. Yoo, Aleksandra Binek, Alina Guo, Julie S. Kim, Jennifer Aguilan, Mohammad Keykhaei, Sydney R. Jenkin, Simone Sidoli, Kavita Sharma, Jennifer E Van Eyk, David A. Kass, Virginia S. Hahn   +12 more
doaj   +1 more source

The emerging role of Nrf2 in heart failure: From cardioprotection to therapeutic approaches

ESC Heart Failure, EarlyView.
Nrf2 signalling is impaired in heart failure, contributing to oxidative stress, mitochondrial dysfunction, and ferroptosis, which drive neurohormonal activation, inflammation, and ischaemia‐reperfusion injury. This loss of Nrf2 activity exacerbates hypertension, diabetic cardiomyopathy, and cardiotoxicity, accelerating progression to overt heart ...
Emiliano Fiori, Sergio Davinelli, Armando Ferrera, Alessandro Medoro, Carlo Barsali, Allegra Battistoni, Maurizio Volterrani, Massimo Volpe, Luciano Saso, Speranza Rubattu   +9 more
wiley   +1 more source

Heart Failure with preserved Ejection Fraction (HFpEF); A Mexican cohort from Mexican Institute of Social Security (IMSS) [PDF]

, 2019
Peralta MR
openalex   +1 more source

The Importance of Controlling Comorbidities in HFpEF and How They Influence Disease Evolution [PDF]

, 2022
Conrado Roberto Hoffmann Filho, André Rodrigues Durães, Gilmar Sidnei Erzinger   +2 more
openalex   +1 more source

A novel treatment score (QUAD score) to promote treatment optimization in heart failure with a reduced ejection fraction

ESC Heart Failure, EarlyView.
The QUAD score was developed to promote adherence to clinical practice guidelines for patients with heart failure and a reduced left ventricular ejection fraction <50%. In newly diagnosed patients who had completed therapy titration, we found that patients with an excellent QUAD score had a significant reduction in the risk of mortality or ...
Henry Oluwasefunmi Savage, Jason N. Dungu, Anthony Dimarco, Brian Li, Samantha Langley, Jonathan Kojo Amoah, Paraic Cliffe, Archana Ganapathy, Peter Watters, Patricia Campbell, Nicola Melarkey, Simon Duckett, Sean Davies, Matthew Dewhurst, Karen Hann, Louise Clayton, Rhys Williams, Victoria Ruszala, Teresa Onwere‐Tan, Fozia Zahir Ahmed, Ibrahim Arosi, Kimberly Gray, Mark C. Petrie, John G.F. Cleland   +23 more
wiley   +1 more source

SGLT2 inhibitors for the prevention and treatment of heart failure: A scientific statement of the HFA and the HFAI

ESC Heart Failure, EarlyView.
Abstract In the 2021 European Society of Cardiology (ESC) heart failure (HF) guidelines, sodium–glucose cotransporter 2 (SGLT2) inhibitors were recommended for the prevention of HF in patients with type 2 diabetes mellitus (T2DM) and for the treatment of HF with reduced ejection fraction (HFrEF).
Marco Metra, Daniela Tomasoni, Marianna Adamo, Offer Amir, Stefan D. Anker, Antoni Bayes‐Genis, Michael Boehm, Javed Butler, Ovidiu Chioncel, Gerasimos Filippatos, Finn Gustafsson, Ewa A. Jankowska, Juan Carlos Kaski, Brenda Moura, Mark C. Petrie, Piotr Ponikowski, Amina Rakisheva, Arsen Ristic, Francois Roubille, Gianluigi Savarese, Petar Seferovic, Peter van der Meer, Maurizio Volterrani, Andrew J. Coats, Vijay K. Chopra, Giuseppe Rosano   +25 more
wiley   +1 more source

Poor cardiovascular outcomes of underweight abdominal obesity in the entire population of newly diagnosed heart failure

ESC Heart Failure, EarlyView.
Abstract Aims Body mass index (BMI) has been widely used as a simple tool for predicting cardiovascular risk. Here we aimed to analyse the distribution and cardiovascular outcomes according to BMI and waist circumference (WC) of the newly diagnosed heart failure (HF) patients in the entire population of the Republic of Korea for 10 years.
Joongmin Kim, Sungyoun Chun, Jong‐Kwan Park, Hancheol Lee, Ji‐Yong Jang, Hyeongsoo Kim, Geunhee Park, Seung‐Jin Oh, Se‐Jung Yoon   +8 more
wiley   +1 more source

Metabolic Syndrome Nonalcoholic Steatohepatitis Male Mouse With Adeno‐Associated Viral Renin as a Novel Model for Heart Failure With Preserved Ejection Fraction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Heart failure with preserved ejection fraction (HFpEF) currently accounts for more than half of patients with HF, with limited approved evidence‐based therapies.
Yuji Shi, Patricia Perez‐Bonilla, Xian Chen, Kelly Tam, Mackenzie Marshall, Jeffrey Morin, Brianna LaViolette, Nouaying R. Kue, Federico Damilano, Russell A. Miller, Bei B. Zhang, Rachel J. Roth Flach, Dinesh Hirenallur‐Shanthappa   +12 more
doaj   +1 more source

Interatrial shunt device for HFpEF [PDF]

, 2017
Gregory B. Lim
openalex   +1 more source

Longitudinal characterization of clinically relevant haemodynamics in conscious Ossabaw pigs with HFpEF [PDF]

, 2022
Jakob Balitzki, Johann Bauersachs, Thomas Thum, Joerg Hueser, Peter Sandner, T Mondritzki   +5 more
openalex   +1 more source