Results 161 to 170 of about 36,198 (299)

Comparative analysis of metabolic and functional cardiac alterations in diet‐ and genetically induced mouse models of cardiac dysfunction

The FEBS Journal, EarlyView.
Dietary and genetic stress trigger different routes to heart failure. In mice, a carbohydrate‐free high‐fat diet caused mitochondrial dysfunction and impaired energy production with preserved pumping function, while genetic obesity led to heart enlargement, fibrosis, and reduced function.
Christiane Ott, Patricia Baumgarten, Thorsten Henning, Daniela Weber, Iwona Wallach, Jana Grune, Ulrich Kintscher, Hermann‐Georg Holzhütter, Tilman Grune, Nikolaus Berndt   +9 more
wiley   +1 more source

Phenotyping of acute heart failure with preserved ejection fraction: real‐world outcomes in a cohort of older patients

Internal Medicine Journal, EarlyView.
Abstract Background Previous studies have identified distinct subgroups (phenogroups) of patients with heart failure with preserved ejection fraction (HFpEF). Aims This study aims to identify distinct phenotypes in older patients with HFpEF hospitalised for acute heart failure (AHF) and investigate the relationship between subgroups and outcomes ...
Maria Livia Burzo *, Giuseppe De Matteis, Amato Serra, Davide Antonio Della Polla, Mariella Fuorlo, Maria Anna Nicolazzi, Benedetta Simeoni, Antonio Gasbarrini, Francesco Franceschi, Giovanni Gambassi, Marcello Covino   +10 more
wiley   +1 more source

Reply to the Letter to the Editor: “Revisiting Triglyceride-Glucose Index in HCM and HFpEF: Clarifying Confounders and Interpretative Limitations” [PDF]

Yi Zheng
openalex   +1 more source

The urinary albumin‐to‐creatinine ratio can direct personalized prevention and treatment for cardiovascular and chronic kidney disease

Journal of Internal Medicine, EarlyView.
Abstract Increased urinary albumin excretion is a strong predictor for cardiovascular events in persons with and without decreased glomerular filtration rate and can be assessed with the urinary albumin‐to‐creatinine ratio (UACR), which is a selective, sensitive, and convenient method for patients.
Holly J. Kramer, George L. Bakris
wiley   +1 more source

Dapagliflozin and Spironolactone Improved Clinical Symptoms and CV Outcomes in Patient with HF Preserved Ejection Fraction (HFpEF) in Hard-to-Reach Rural African Population: A Case Series

, 2022
Dominick Mkombozi Raphael, Abdu Hussein Mogella, Elias Edrick Mtalemwa, Beatrice Kabuka   +3 more
openalex   +2 more sources

Nocturnal Hypoxemic Burden Predicts Mortality in Patients Awaiting Heart Transplantation

Journal of Sleep Research, EarlyView.
Trial design and results on hypoxemic burden in the context of heart transplantation. ABSTRACT Risk stratification for patients with end‐stage heart failure (HF) awaiting heart transplantation (HTX) is crucial. Sleep‐disordered breathing (SDB) is a prevalent comorbidity, yet the impact of its resultant hypoxemic burden remains unclear in this ...
Max Potratz, Tatevik Manukyan, René Schramm, Angelika Costard‐Jäckle, Uwe Fuchs, Michiel Morshuis, Sabina P. W. Guenther, Sebastian V. Rojas, Volker Rudolph, Jan F. Gummert, Henrik Fox   +10 more
wiley   +1 more source

Impact of Structured Resistance Training on Locomotor Muscle Composition in Patients with HFpEF [PDF]

, 2023
Salaheddin M. Sharif, Joshua R. Smith, Eric J. Bruhn, Adam M. Shultz, Thomas P. Olson   +4 more
openalex   +1 more source

GLP‐1 Receptor Agonists for the Prevention of New‐Onset Heart Failure: A Systematic Review and Meta‐Analysis of Placebo‐Controlled Randomized Clinical Trials

Obesity Reviews, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RA) improve outcomes in heart failure (HF) with preserved ejection fraction. Whether GLP‐1 RA prevent new‐onset HF in Type 2 diabetes or obesity requires further investigation. Methods We performed an updated meta‐analysis of randomized placebo‐controlled trials (RCT) of treatment ...
João Sérgio Neves, Carolina B. Lobato, Ana Rita Leite, Catarina Vale, Francisco Vasques‐Nóvoa, Francisca Saraiva, Adelino Leite‐Moreira, Jens J. Holst, João Pedro Ferreira   +8 more
wiley   +1 more source

The year in cardiology: heart failure 2014 [PDF]

, 2017
The year 2014 has become a remarkable year for heart failure. A bad start was caused by the publication of TOPCAT, showing that spironolactone did not prove to be beneficial for the treatment of patients with heart failure and preserved ejection fraction
Ruschitzka, Frank, Voors, Adriaan A.
core  

Mechanisms and outcomes of heart failure: from HFpEF, HFmrEF, and HFrEF to transplantation [PDF]

, 2018
Thomas F. Lüscher
openalex   +1 more source