Results 1 to 10 of about 11,459 (235)

The Power Duo: How the Interplay Between Nucleoid-Associated Proteins and Small Noncoding RNAs Orchestrates the Cellular Regulatory Symphony. [PDF]

open access: yesMol Microbiol
Nucleoid‐associated proteins play a crucial role in the compaction of bacterial DNA and the regulation of gene expression. The emergence of small noncoding RNAs as regulatory elements in these processes represents a major development in our understanding of bacterial biology.
Moutacharrif S   +6 more
europepmc   +2 more sources

Involvement of the post-transcriptional regulator Hfq in Yersinia pestis virulence. [PDF]

open access: goldPLoS ONE, 2009
BACKGROUND:Yersinia pestis is the causative agent of plague, which is transmitted primarily between fleas and mammals and is spread to humans through the bite of an infected flea or contact with afflicted animals.
Jing Geng   +13 more
doaj   +3 more sources

Extracellular Vesicles From Xylella fastidiosa Carry sRNAs and Genomic Islands, Suggesting Roles in Recipient Cells. [PDF]

open access: yesJ Extracell Vesicles
ABSTRACT Xylella fastidiosa (Xf) is a Gram‐negative bacterial plant pathogen responsible for severe diseases in a variety of economically important crops. A critical aspect of its virulence is the production of extracellular vesicles (EVs). In this study, we discovered that DNA‐binding proteins and nonribosomal RNA‐binding proteins are abundant in the ...
Ruf A   +9 more
europepmc   +2 more sources

Polyphosphate: The "Dark Matter" of Bacterial Chromatin Structure. [PDF]

open access: yesMol Microbiol
Polyphosphate condensates and their contributions to nucleoid structure. Polyphosphate condensates form in the ribosome‐depleted nucleoid region of bacterial cells, particularly under stress (in this case Pseudomonas aeruginosa undergoing nitrogen starvation; adapted with permission from (Racki et al. 2017)). This Perspective explores the emerging view
Racki LR, Freddolino L.
europepmc   +2 more sources

The Sinorhizobium meliloti RNA chaperone Hfq influences central carbon metabolism and the symbiotic interaction with alfalfa [PDF]

open access: goldBMC Microbiology, 2010
Background The bacterial Hfq protein is able to interact with diverse RNA molecules, including regulatory small non-coding RNAs (sRNAs), and thus it is recognized as a global post-transcriptional regulator of gene expression. Loss of Hfq has an extensive
Jiménez-Zurdo José I   +7 more
doaj   +2 more sources

The RNA chaperone Hfq has a multifaceted role in Edwardsiella ictaluri [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology
Edwardsiella ictaluri is a Gram-negative, facultative intracellular bacterium that causes enteric septicemia in catfish (ESC). The RNA chaperone Hfq (host factor for phage Qβ replication) facilitates gene regulation via small RNAs (sRNAs) in various ...
Ali Akgul   +6 more
doaj   +2 more sources

Integrated Hfq-interacting RNAome and transcriptomic analysis reveals complex regulatory networks of nitrogen fixation in root-associated Pseudomonas stutzeri A1501 [PDF]

open access: yesmSphere
The RNA chaperone Hfq acts as a global regulator of numerous biological processes, such as carbon/nitrogen metabolism and environmental adaptation in plant-associated diazotrophs; however, its target RNAs and the mechanisms underlying nitrogen fixation ...
Fanyang Lv   +13 more
doaj   +2 more sources

The RNA chaperone Hfq is involved in stress tolerance and virulence in uropathogenic Proteus mirabilis. [PDF]

open access: yesPLoS ONE, 2014
Hfq is a bacterial RNA chaperone involved in the riboregulation of diverse genes via small noncoding RNAs. Here, we show that Hfq is critical for the uropathogenic Proteus mirabilis to effectively colonize the bladder and kidneys in a murine urinary ...
Min-Cheng Wang   +4 more
doaj   +1 more source

444 Post-translational role of RNA modifications in sRNA chaperone Hfq

open access: yesJournal of Clinical and Translational Science, 2022
OBJECTIVES/GOALS: The goal of this study is to determine the role of the tRNA modifications in the translation of Hfq. Hfq is an RNA chaperone that acts as a co-factor for the action of the largest class of small RNAs in E. coli.
Jalisa Nurse   +2 more
doaj   +1 more source

The RNA chaperone Hfq impacts growth, metabolism and production of virulence factors in Yersinia enterocolitica. [PDF]

open access: yesPLoS ONE, 2014
To adapt to changes in environmental conditions, bacteria regulate their gene expression at the transcriptional but also at the post-transcriptional level, e.g. by small RNAs (sRNAs) which modulate mRNA stability and translation.
Tamara Kakoschke   +6 more
doaj   +1 more source

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