Results 1 to 10 of about 5,373 (162)

Role of the Sinorhizobium meliloti Global Regulator Hfq in Gene Regulation and Symbiosis

open access: yesMolecular Plant-Microbe Interactions, 2010
The RNA-binding protein Hfq is a global regulator which controls diverse cellular processes in bacteria. To begin understanding the role of Hfq in the Sinorhizobium meliloti–Medicago truncatula nitrogen-fixing symbiosis, we defined free-living and ...
Mengsheng Gao   +3 more
doaj   +1 more source

Impact of Hfq on the Bacillus subtilis transcriptome. [PDF]

open access: yesPLoS ONE, 2014
The RNA chaperone Hfq acts as a central player in post-transcriptional gene regulation in several Gram-negative Bacteria, whereas comparatively little is known about its role in Gram-positive Bacteria.
Hermann Hämmerle   +5 more
doaj   +1 more source

Adaptive Tolerance of Listeria monocytogenes to Chemical Oxidants: Comparative Analysis of Transcriptomic Studies

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 24, Issue 5, September 2025.
ABSTRACT Listeria monocytogenes is a foodborne pathogen that poses significant challenges to food safety and public health due to its ability to adapt to harsh environments, particularly those found in food processing facilities. This review explores the global transcriptional responses of L.
Nagendran Rajalingam, Sam Van Haute
wiley   +1 more source

Acinetobacter baumannii as a Model for the Study and Application of Gram‐Negative Outer Membrane Vesicles: A Systematic Review

open access: yesMicrobial Biotechnology, Volume 18, Issue 9, September 2025.
Investigation of outer membrane vesicles from Acinetobacter baumannii for potential biotechnological applications. ABSTRACT Outer membrane vesicles (OMVs) are extracellular nanostructures released from Gram‐negative bacteria. Acinetobacter baumannii OMVs (AbOMVs) have been extensively studied and can thus be used as a model for understanding multiple ...
Beatriz Cano‐Castaño   +5 more
wiley   +1 more source

Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding

open access: yesFEBS Letters, Volume 599, Issue 16, Page 2318-2333, August 2025.
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter   +8 more
wiley   +1 more source

RNA binding of Hfq monomers promotes RelA-mediated hexamerization in a limiting Hfq environment

open access: yesNature Communications, 2021
RelA stimulates RyhB small RNA–target mRNA interaction by promoting assembly of Hfq monomers into hexamers. Here the authors show that RelA-mediated Hfq hexamerization requires an initial binding of RNA to Hfq monomers.
Pallabi Basu   +5 more
doaj   +1 more source

Phage‐mediated horizontal transfer of Salmonella enterica virulence genes with regulatory feedback from the host

open access: yesiMeta, Volume 4, Issue 4, August 2025.
In this study, we found evidence of phage‐mediated horizontal transfer of virulence genes in Salmonella enterica in global habitats from a molecular evolutionary perspective. Notably, csrA, a global regulator in Salmonella enterica, curbed horizontal gene transfer by inhibiting the cyclization and release of prophage.
Tianjing She   +9 more
wiley   +1 more source

Conserved mycobacterial sRNA B11 regulates lipooligosaccharide synthesis at posttranscriptional level in Mycobacterium marinum

open access: yesmLife, Volume 4, Issue 4, Page 447-460, August 2025.
Abstract Extractable glycolipids of mycobacteria, such as lipooligosaccharides (LOSs), play crucial roles in responding to environmental stress and modulating the host immune response. Although the biosynthesis of LOS is likely regulated at multiple levels to ensure proper composition of the cell wall, the key regulators remain unknown.
Chuan Wang   +6 more
wiley   +1 more source

Epigallocatechin Gallate Remodelling of Hfq Amyloid-Like Region Affects Escherichia coli Survival

open access: yesPathogens, 2018
Hfq is a pleiotropic regulator that has key roles in the control of genetic expression. The protein noticeably regulates translation efficiency and RNA decay in Gram-negative bacteria, due to the Hfq-mediated interaction between small regulatory ...
David Partouche   +7 more
doaj   +1 more source

Microfluidic Devices for Manufacture of Therapeutic Extracellular Vesicles: Advances and Opportunities

open access: yesJournal of Extracellular Vesicles, Volume 14, Issue 7, July 2025.
ABSTRACT Extracellular vesicles (EVs) are emerging as promising candidates in therapeutic applications due to their unique ability to mediate intercellular communication and deliver biological cargo. With increasing interest in EV‐based therapies, the development of scalable, cost‐effective and regulatory‐compliant production methods is critical ...
Amin Hassanzadeh‐Barforoushi   +4 more
wiley   +1 more source

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