Results 101 to 110 of about 11,687 (237)

On the facultative requirement of the bacterial RNA chaperone, Hfq [PDF]

Trends in Microbiology, 2009
The pleiotropic post-transcriptional regulator Hfq is an RNA chaperone that facilitates pairing interactions between small regulatory RNAs (sRNAs) and their mRNA targets in several bacteria. However, this classical pattern, derived from the Escherichia coli model, is not applicable to the whole bacterial kingdom.
Jousselin, Ambre, Metzinger, Laurent, Felden, Brice   +2 more
openaire   +3 more sources

Role of the Bacterial Amyloid-like Hfq in Fluoroquinolone Fluxes

Microorganisms, 2023
Due to their two-cell membranes, Gram-negative bacteria are particularly resistant to antibiotics. Recent investigations aimed at exploring new target proteins involved in Gram-negative bacteria adaptation helped to identify environmental changes encountered during infection.
Turbant, Florian, Esnouf, Emeline, Rosaz, Francois, Wien, Frank, Węgrzyn, Grzegorz, Chauvet, Hugo, Arluison, Véronique   +6 more
openaire   +4 more sources

Epigallocatechin Gallate Remodelling of Hfq Amyloid-Like Region Affects Escherichia coli Survival

Pathogens, 2018
Hfq is a pleiotropic regulator that has key roles in the control of genetic expression. The protein noticeably regulates translation efficiency and RNA decay in Gram-negative bacteria, due to the Hfq-mediated interaction between small regulatory ...
David Partouche, Florian Turbant, Omar El Hamoui, Camille Campidelli, Marianne Bombled, Sylvain Trépout, Frank Wien, Véronique Arluison   +7 more
doaj   +1 more source

The Quorum Sensing Regulated sRNA Lrs1 Is Involved in the Adaptation to Low Iron in Pseudomonas aeruginosa

Environmental Microbiology Reports, Volume 17, Issue 2, April 2025.
The quorum sensing regulated sRNA Lrs1 participates in the adaptation of Pseudomonas aeruginosa in low iron by downregulating the siderophore pyochelin, the Quorum Sensing system PQS, and its associated virulence factor phenazines. ABSTRACT Iron is an essential nutrient for microbial growth. The opportunistic pathogen Pseudomonas aeruginosa can survive
Dimitra Panagiotopoulou, Natalia Romo Catalán, Max Wilcox, Nigel Halliday, Paolo Pantalone, James Lazenby, Miguel Cámara, Stephan Heeb   +7 more
wiley   +1 more source

Characterization of Aptamer-Protein Complexes by X-ray Crystallography and Alternative Approaches [PDF]

, 2012
Aptamers are oligonucleotide ligands, either RNA or ssDNA, selected for high-affinity binding to molecular targets, such as small organic molecules, proteins or whole microorganisms.
Baugh, Bauke W. Dijkstra, Bing, Bock, Cao, Chayen, Convery, Doudna, Ellington, Friedmann, Garber, Hauke Smidt, Hermann, Hianik, Hoggan, Hollis, Horn, Huang, Huang, Hwang, Jiang, Johan Hekelaar, John van der Oost, Kaur, Ke, Kelly, Kikin, Krauss, Kwan, Laing, Lebruska, Lee, Long, Lupold, Macaya, Mark Levisson, Mascini, McPherson, Mehta, Miyakawa, Moorthy, Murai, Nix, Nomura, Orlova, Padmanabhan, Padmanabhan, Paige, Parisien, Poniková, Reinemann, Reinstein, Renault, Rivas, Rowsell, Ruigrok, Sekiya, Shum, Skrzypczak-Jankun, Snyder, Someya, Stoltenburg, Sugiyama, Sussman, Tereshko, Tuerk, Vincent J. B. Ruigrok, Wang, Wilson, Win, Wochner, Yan, Yee, Zuker   +73 more
core   +6 more sources

Identification, characterization and classification of prokaryotic nucleoid‐associated proteins

Molecular Microbiology, Volume 123, Issue 3, Page 206-217, March 2025.
Nucleoid‐associated proteins (NAPs) structure DNA by either bending, wrapping, bridging, or forming protein filaments on the DNA. We review newly identified NAPs and provide a list of simple biochemical assays to study the DNA‐structuring properties of novel NAPs. Abstract Common throughout life is the need to compact and organize the genome.
Samuel Schwab, Remus T. Dame
wiley   +1 more source

Interplay between the catabolite repression control protein Crc, Hfq and RNA in Hfq-dependent translational regulation in Pseudomonas aeruginosa [PDF]

Nucleic Acids Research, 2017
In Pseudomonas aeruginosa the RNA chaperone Hfq and the catabolite repression control protein (Crc) act as post-transcriptional regulators during carbon catabolite repression (CCR). In this regard Crc is required for full-fledged Hfq-mediated translational repression of catabolic genes. RNAseq based transcriptome analyses revealed a significant overlap
Michael T. Wolfinger, Michael T. Wolfinger, Elisabeth Sonnleitner, Giada Forlani, Sébastien Campagne, Alexander Wulf, Laetitia Abdou, Xue-Yuan Pei, Frédéric H.-T. Allain, Armin Resch, Bonaventura Francesco Luisi, Udo Bläsi, Konstantin Prindl, Henning Urlaub   +13 more
openaire   +10 more sources

The RNA Chaperone Hfq Is Involved in Colony Morphology, Nutrient Utilization and Oxidative and Envelope Stress Response in Vibrio alginolyticus. [PDF]

PLoS ONE, 2016
Hfq is a global regulator that is involved in environmental adaptation of bacteria and in pathogenicity. To gain insight into the role of Hfq in Vibrio alginolyticus, an hfq deletion mutant was constructed in V.
Yiqin Deng, Chang Chen, Zhe Zhao, Jingjing Zhao, Annick Jacq, Xiaochun Huang, Yiying Yang   +6 more
doaj   +1 more source

Chromatin and gene regulation in archaea

Molecular Microbiology, Volume 123, Issue 3, Page 218-231, March 2025.
Recent data from diverse archaea with different repertoires of nucleoid‐associated proteins show a common genome‐wide chromatin organisation where chromatin maintains access to gene promoters independently of transcription activity. Abstract The chromatinisation of DNA by nucleoid‐associated proteins (NAPs) in archaea ‘formats’ the genome structure in ...
Fabian Blombach, Finn Werner
wiley   +1 more source

Identification of protein-protein and ribonucleoprotein complexes containing Hfq [PDF]

Scientific Reports, 2019
AbstractHfq is a RNA-binding protein that plays a pivotal role in the control of gene expression in bacteria by stabilizing sRNAs and facilitating their pairing with multiple target mRNAs. It has already been shown that Hfq, directly or indirectly, interacts with many proteins: RNase E, Rho, poly(A)polymerase, RNA polymerase… In order to detect more ...
Caillet, Joël, Baron, Bruno, Boni, Irina, Caillet-Saguy, Celia, Hajnsdorf, Eliane   +4 more
openaire   +4 more sources