Results 111 to 120 of about 11,687 (237)

Quick change: post-transcriptional regulation in Pseudomonas [PDF]

open access: yes, 2017
Pseudomonas species have evolved dynamic and intricate regulatory networks to fine-tune gene expression, with complex regulation occurring at every stage in the processing of genetic information.
Afonyushkin   +76 more
core   +1 more source

Functional Characterization of a Global Virulence Regulator Hfq and Identification of Hfq-Dependent sRNAs in the Plant Pathogen Pantoea ananatis

open access: yesFrontiers in Microbiology, 2019
To successfully infect plant hosts, the collective regulation of virulence factors in a bacterial pathogen is crucial. Hfq is an RNA chaperone protein that facilitates the small RNA (sRNA) regulation of global gene expression at the post-transcriptional ...
Gi Yoon Shin   +7 more
doaj   +1 more source

DNMT3a Downregulation Ttriggered Upregulation of GABAA Receptor in the mPFC Promotes Paclitaxel‐Induced Pain and Anxiety in Male Mice

open access: yesAdvanced Science, Volume 12, Issue 5, February 3, 2025.
Paclitaxel induces DNMT3a‐dependent DNA hypomethylation in the mPFC, which contributes to paclitaxel‐induced hyperalgesia and anxiety by upregulating GABAA receptors and enhancing inhibitory transmission in mPFC glutamatergic neurons. Strategies that increase DNA methylation, such as a long‐term methyl donor diet, may offer benefits for managing ...
Lixia Tian   +10 more
wiley   +1 more source

Multifunctional ZnO Nanoparticles Synthesized Using Spirodela polyrhiza Extract: Characterization, Photocatalytic Activity, Antimicrobial Assessment, and In Silico Modeling

open access: yesBioinorganic Chemistry and Applications, Volume 2025, Issue 1, 2025.
This study investigates the green synthesis of zinc oxide nanoparticles (ZnO NPs) using the aqueous extract of the aquatic plant Spirodela polyrhiza (greater duckweed) and evaluates their multifunctional properties. The ZnO NPs were synthesized via a sustainable method and characterized using UV‐visible spectroscopy, TEM, FESEM, EDX, FTIR, and XRD ...
Azmat Ali Khan   +6 more
wiley   +1 more source

Distinctive Regulation of Carbapenem Susceptibility in Pseudomonas aeruginosa by Hfq

open access: yesFrontiers in Microbiology, 2020
Carbapenems are often the antibiotics of choice to combat life threatening infections caused by the opportunistic human pathogen Pseudomonas aeruginosa. The outer membrane porins OprD and OpdP serve as entry ports for carbapenems.
Elisabeth Sonnleitner   +4 more
doaj   +1 more source

Twofold Video Hashing with Automatic Synchronization

open access: yes, 2014
Video hashing finds a wide array of applications in content authentication, robust retrieval and anti-piracy search. While much of the existing research has focused on extracting robust and secure content descriptors, a significant open challenge still ...
Li, Mu, Monga, Vishal
core   +1 more source

Discovery of high-frequency quasi-periodic oscillations in the black-hole candidate IGR J17091-3624

open access: yes, 2012
We report the discovery of 8.5 sigma high-frequency quasi-periodic oscillations (HFQPOs) at 66 Hz in the RXTE data of the black hole candidate IGR J17091-3624, a system whose X-ray properties are very similar to those of microquasar GRS 1915+105.
Altamirano, Diego, Belloni, Tomaso
core   +1 more source

Isofunctional but Structurally Different Methyltransferases for Dithiolopyrrolone Diversification

open access: yesAngewandte Chemie, Volume 136, Issue 49, December 2, 2024.
Two for one job: DtpM and XrdM are two bacterial enzymes that have different structures but still catalyze the same reaction: the amide N‐methylation of dithiolopyrrolones (DTPs). Ligand binding to both enzymes was studied using X‐ray crystallography, modeling, mutagenesis and activity assays.
Li Su   +13 more
wiley   +1 more source

Deletion of the small RNA chaperone protein Hfq down regulates genes related to virulence and confers protection against wild-type Brucella challenge in mice

open access: yesFrontiers in Microbiology, 2016
Brucellosis is one of the most common zoonotic epidemics worldwide. Brucella, the etiological pathogen of brucellosis, has unique virulence characteristics, including the ability to survive within the host cell.
Shuangshuang eLei   +15 more
doaj   +1 more source

The RNA chaperone Hfq has a multifaceted role in Edwardsiella ictaluri

open access: yesFrontiers in Cellular and Infection Microbiology
Edwardsiella ictaluri is a Gram-negative, facultative intracellular bacterium that causes enteric septicemia in catfish (ESC). The RNA chaperone Hfq (host factor for phage Qβ replication) facilitates gene regulation via small RNAs (sRNAs) in various ...
Ali Akgul   +6 more
doaj   +1 more source

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