Results 111 to 120 of about 11,459 (235)
Compensatory evolution of chromosomes and plasmids counteracts the plasmid fitness cost
In this review, we provide a comprehensive overview of the currently reported mechanisms underlying compensatory evolution on chromosomes and plasmids, elucidate key targets regulating plasmid fitness cost, and discuss future challenges in this field.
Ziyi Liu+3 more
wiley +1 more source
Interconnection of post-transcriptional regulation: The RNA-binding protein Hfq is a novel target of the Lon protease in Pseudomonas aeruginosa [PDF]
Besides being a major opportunistic human pathogen, Pseudomonas aeruginosa can be found in a wide range of environments. This versatility is linked to complex regulation, which is achieved through the action of transcriptional regulators, and post ...
Bains, Manjeet+7 more
core +1 more source
Identification of protein-protein and ribonucleoprotein complexes containing Hfq [PDF]
AbstractHfq is a RNA-binding protein that plays a pivotal role in the control of gene expression in bacteria by stabilizing sRNAs and facilitating their pairing with multiple target mRNAs. It has already been shown that Hfq, directly or indirectly, interacts with many proteins: RNase E, Rho, poly(A)polymerase, RNA polymerase… In order to detect more ...
Caillet, Joël+4 more
openaire +4 more sources
Distinctive Regulation of Carbapenem Susceptibility in Pseudomonas aeruginosa by Hfq
Carbapenems are often the antibiotics of choice to combat life threatening infections caused by the opportunistic human pathogen Pseudomonas aeruginosa. The outer membrane porins OprD and OpdP serve as entry ports for carbapenems.
Elisabeth Sonnleitner+4 more
doaj +1 more source
This review examines discoveries of biomolecular condensates as compartments in bacteria. Insights from bacterial cell biology and systems chemistry reveal intricate connections between chemical reactions and the control of condensate phase separation.
Wade E. Schnorr, W. Seth Childers
wiley +1 more source
The orthosymplectic superalgebra in harmonic analysis [PDF]
We introduce the orthosymplectic superalgebra osp(m|2n) as the algebra of Killing vector fields on Riemannian superspace R^{m|2n} which stabilize the origin. The Laplace operator and norm squared on R^{m|2n}, which generate sl(2), are orthosymplectically
Coulembier, Kevin
core
Nuclear spin squeezing via electric quadrupole interaction [PDF]
Control over nuclear spin fluctuations is essential for processes that rely on preserving the quantum state of an embedded system. For this purpose, squeezing is a viable alternative, so far that has not been properly exploited for the nuclear spins.
Bulutay, Ceyhun, Korkmaz, Yağmur Aksu
core +2 more sources
Brucellosis is one of the most common zoonotic epidemics worldwide. Brucella, the etiological pathogen of brucellosis, has unique virulence characteristics, including the ability to survive within the host cell.
Shuangshuang eLei+15 more
doaj +1 more source
The E. coli rpoN operon encodes important regulatory proteins including sigma 54 and components of the nitrogen‐related PTS. Here we show that additional upstream and internally located promoters contribute to its transcription in response to distinct envelope stress conditions and carbon source quality. RNase E cleaves transcripts extensively upstream
Florian Sikora+5 more
wiley +1 more source
Bacterial small noncoding RNAs (sRNAs) play posttranscriptional regulatory roles in cellular responses to changing environmental cues and in adaptation to harsh conditions. Generally, the RNA-binding protein Hfq helps sRNAs associate with target mRNAs to
Kotaro Chihara+6 more
doaj +1 more source