Results 111 to 120 of about 11,459 (235)

Compensatory evolution of chromosomes and plasmids counteracts the plasmid fitness cost

open access: yesEcology and Evolution, Volume 14, Issue 8, August 2024.
In this review, we provide a comprehensive overview of the currently reported mechanisms underlying compensatory evolution on chromosomes and plasmids, elucidate key targets regulating plasmid fitness cost, and discuss future challenges in this field.
Ziyi Liu   +3 more
wiley   +1 more source

Interconnection of post-transcriptional regulation: The RNA-binding protein Hfq is a novel target of the Lon protease in Pseudomonas aeruginosa [PDF]

open access: yes, 2015
Besides being a major opportunistic human pathogen, Pseudomonas aeruginosa can be found in a wide range of environments. This versatility is linked to complex regulation, which is achieved through the action of transcriptional regulators, and post ...
Bains, Manjeet   +7 more
core   +1 more source

Identification of protein-protein and ribonucleoprotein complexes containing Hfq [PDF]

open access: yesScientific Reports, 2019
AbstractHfq is a RNA-binding protein that plays a pivotal role in the control of gene expression in bacteria by stabilizing sRNAs and facilitating their pairing with multiple target mRNAs. It has already been shown that Hfq, directly or indirectly, interacts with many proteins: RNase E, Rho, poly(A)polymerase, RNA polymerase… In order to detect more ...
Caillet, Joël   +4 more
openaire   +4 more sources

Distinctive Regulation of Carbapenem Susceptibility in Pseudomonas aeruginosa by Hfq

open access: yesFrontiers in Microbiology, 2020
Carbapenems are often the antibiotics of choice to combat life threatening infections caused by the opportunistic human pathogen Pseudomonas aeruginosa. The outer membrane porins OprD and OpdP serve as entry ports for carbapenems.
Elisabeth Sonnleitner   +4 more
doaj   +1 more source

Biomolecular Condensates: From Bacterial Compartments to Incubator Spaces of Emergent Chemical Systems in Matter‐to‐Life Transitions

open access: yesChemSystemsChem, Volume 6, Issue 4, July 2024.
This review examines discoveries of biomolecular condensates as compartments in bacteria. Insights from bacterial cell biology and systems chemistry reveal intricate connections between chemical reactions and the control of condensate phase separation.
Wade E. Schnorr, W. Seth Childers
wiley   +1 more source

The orthosymplectic superalgebra in harmonic analysis [PDF]

open access: yes, 2012
We introduce the orthosymplectic superalgebra osp(m|2n) as the algebra of Killing vector fields on Riemannian superspace R^{m|2n} which stabilize the origin. The Laplace operator and norm squared on R^{m|2n}, which generate sl(2), are orthosymplectically
Coulembier, Kevin
core  

Nuclear spin squeezing via electric quadrupole interaction [PDF]

open access: yes, 2016
Control over nuclear spin fluctuations is essential for processes that rely on preserving the quantum state of an embedded system. For this purpose, squeezing is a viable alternative, so far that has not been properly exploited for the nuclear spins.
Bulutay, Ceyhun, Korkmaz, Yağmur Aksu
core   +2 more sources

Deletion of the small RNA chaperone protein Hfq down regulates genes related to virulence and confers protection against wild-type Brucella challenge in mice

open access: yesFrontiers in Microbiology, 2016
Brucellosis is one of the most common zoonotic epidemics worldwide. Brucella, the etiological pathogen of brucellosis, has unique virulence characteristics, including the ability to survive within the host cell.
Shuangshuang eLei   +15 more
doaj   +1 more source

Multiple regulatory inputs including cell envelope stress orchestrate expression of the Escherichia coli rpoN operon

open access: yesMolecular Microbiology, Volume 122, Issue 1, Page 11-28, July 2024.
The E. coli rpoN operon encodes important regulatory proteins including sigma 54 and components of the nitrogen‐related PTS. Here we show that additional upstream and internally located promoters contribute to its transcription in response to distinct envelope stress conditions and carbon source quality. RNase E cleaves transcripts extensively upstream
Florian Sikora   +5 more
wiley   +1 more source

Conditional Hfq Association with Small Noncoding RNAs in Pseudomonas aeruginosa Revealed through Comparative UV Cross-Linking Immunoprecipitation Followed by High-Throughput Sequencing

open access: yesmSystems, 2019
Bacterial small noncoding RNAs (sRNAs) play posttranscriptional regulatory roles in cellular responses to changing environmental cues and in adaptation to harsh conditions. Generally, the RNA-binding protein Hfq helps sRNAs associate with target mRNAs to
Kotaro Chihara   +6 more
doaj   +1 more source

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