Results 11 to 20 of about 11,459 (235)
Staphylococcus aureus pigmentation is not controlled by Hfq [PDF]
BMC Research Notes, 2020 Objective The golden color of Staphylococcus aureus is due to the synthesis of carotenoid pigments. In Gram-negative bacteria, Hfq is a global posttranscriptional regulator, but its function in S. aureus remains obscure. The absence of Hfq in S.
Wenfeng Liu +3 more
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Association of RNAs with Bacillus subtilis Hfq. [PDF]
PLoS ONE, 2013 The prevalence and characteristics of small regulatory RNAs (sRNAs) have not been well characterized for Bacillus subtilis, an important model system for Gram-positive bacteria. However, B.
Michael Dambach +2 more
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Impact of Hfq on the Bacillus subtilis transcriptome. [PDF]
PLoS ONE, 2014 The RNA chaperone Hfq acts as a central player in post-transcriptional gene regulation in several Gram-negative Bacteria, whereas comparatively little is known about its role in Gram-positive Bacteria.
Hermann Hämmerle +5 more
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Tracking the Elusive Function of Bacillus subtilis Hfq.
PLoS ONE, 2015 RNA-binding protein Hfq is a key component of the adaptive responses of many proteobacterial species including Escherichia coli, Salmonella enterica and Vibrio cholera.
Tatiana Rochat +6 more
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RNA binding of Hfq monomers promotes RelA-mediated hexamerization in a limiting Hfq environment [PDF]
Nature Communications, 2021 RelA stimulates RyhB small RNA–target mRNA interaction by promoting assembly of Hfq monomers into hexamers. Here the authors show that RelA-mediated Hfq hexamerization requires an initial binding of RNA to Hfq monomers.
Pallabi Basu +5 more
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Molecular Cell, 2002 The bacterial Hfq protein modulates the stability or the translation of mRNAs and has recently been shown to interact with small regulatory RNAs in E. coli. Here we show that Hfq belongs to the large family of Sm and Sm-like proteins: it contains a conserved sequence motif, known as the Sm1 motif, forms a doughnut-shaped structure, and has RNA binding ...
Thorleif Møller +6 more
openalex +6 more sources
Pervasive Targeting of Nascent Transcripts by Hfq
Cell Reports, 2018 Summary: Hfq is an RNA chaperone and an important post-transcriptional regulator in bacteria. Using chromatin immunoprecipitation coupled with high-throughput DNA sequencing (ChIP-seq), we show that Hfq associates with hundreds of different regions of ...
Tracy K. Kambara +2 more
doaj +4 more sources
Interaction of the RNA chaperone Hfq with mRNAs: direct and indirect roles of Hfq in iron metabolism of Escherichia coli [PDF]
Molecular Microbiology, 2003 SummaryThe Escherichia coli Sm‐like host factor I (Hfq) is thought to play direct and indirect roles in post‐transcriptional regulation by targeting small regulatory RNAs and mRNAs. In this study, we have used proteomics to identify new mRNA targets of Hfq.
Branislav Večerek +4 more
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An improved method for surface immobilisation of RNA: application to small Non-Coding RNA - mRNA pairing [PDF]
, 2013 Characterisation of RNA and its intermolecular interactions is increasing in importance as the inventory of known RNA functions continues to expand. RNA-RNA interactions are central to post-transcriptional gene regulation mechanisms in bacteria, and the ...
Butt, Louise +9 more
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RNA reflections: converging on Hfq [PDF]
RNA, 2015 As the journal RNA celebrates its 20th anniversary, the role of non-coding RNAs as regulators is firmly established in a broad range of organisms. Among these are the many bacterial RNAs that pair with their targets and regulate mRNA stability and translation. In Escherichia coli and other gram-negative organisms, these small RNAs (sRNAs) depend on Hfq,
Gisela Storz, Susan Gottesman
openaire +3 more sources