Results 21 to 30 of about 11,806 (233)
Hfq is a global regulator that controls the pathogenicity of Staphylococcus aureus. [PDF]
PLoS ONE, 2010 The Hfq protein is reported to be an RNA chaperone, which is involved in the stress response and the virulence of several pathogens. In E. coli, Hfq can mediate the interaction between some sRNAs and their target mRNAs.
Yu Liu +7 more
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Hfq: the flexible RNA matchmaker [PDF]
Current Opinion in Microbiology, 2016 The RNA chaperone protein Hfq is critical to the function of small, base pairing RNAs in many bacteria. In the past few years, structures and modeling of wild type Hfq and assays of various mutants have documented that the homohexameric Hfq ring can contact RNA at four sites (proximal face, distal face, rim and C-terminal tail) and that different RNAs ...
Taylor B Updegrove +2 more
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An improved method for surface immobilisation of RNA: application to small Non-Coding RNA - mRNA pairing [PDF]
, 2013 Characterisation of RNA and its intermolecular interactions is increasing in importance as the inventory of known RNA functions continues to expand. RNA-RNA interactions are central to post-transcriptional gene regulation mechanisms in bacteria, and the ...
Butt, Louise +9 more
core +7 more sources
Hfq and its constellation of RNA [PDF]
Nature Reviews Microbiology, 2011 Hfq is an RNA-binding protein that is common to diverse bacterial lineages and has key roles in the control of gene expression. By facilitating the pairing of small RNAs with their target mRNAs, Hfq affects the translation and turnover rates of specific transcripts and contributes to complex post-transcriptional networks.
Jörg, Vogel, Ben F, Luisi
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Profound impact of Hfq on nutrient acquisition, metabolism and motility in the plant pathogen Agrobacterium tumefaciens. [PDF]
PLoS ONE, 2014 As matchmaker between mRNA and sRNA interactions, the RNA chaperone Hfq plays a key role in riboregulation of many bacteria. Often, the global influence of Hfq on the transcriptome is reflected by substantially altered proteomes and pleiotropic ...
Philip Möller +6 more
doaj +1 more source
eLife, 2021 RNA-binding proteins play myriad roles in regulating RNAs and RNA-mediated functions. In bacteria, the RNA chaperone Hfq is an important post-transcriptional gene regulator.
Seongjin Park +8 more
doaj +1 more source
RNA Biology, 2013 The bacterial Hfq protein is a versatile modulator of RNA function and is particularly important for regulation mediated by small non-coding RNAs. Hfq is a bacterial Sm protein but bears more similarity to the eukaryotic Sm-like (Lsm) family of proteins than the prototypical Sm proteins.
Wilusz, Carol J., Wilusz, Jeffrey
openaire +2 more sources
Overexpression of an outer membrane protein associated with decreased susceptibility to carbapenems in Proteus mirabilis. [PDF]
PLoS ONE, 2015 Proteus mirabilis isolates commonly have decreased susceptibility to imipenem. Previously, we found P. mirabilis hfq mutant was more resistant to imipenem and an outer membrane protein (OMP) could be involved.
Yi-Lin Tsai +6 more
doaj +1 more source
Microorganisms, 2021 Yersinia ruckeri causes outbreaks of enteric redmouth disease in salmon aquaculture all over the world. The transient antibiotic tolerance exhibited by bacterial persisters is commonly thought to be responsible for outbreaks; however, the molecular ...
Iván L. Calderón +5 more
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Involvement of the post-transcriptional regulator Hfq in Yersinia pestis virulence. [PDF]
PLoS ONE, 2009 BACKGROUND:Yersinia pestis is the causative agent of plague, which is transmitted primarily between fleas and mammals and is spread to humans through the bite of an infected flea or contact with afflicted animals.
Jing Geng +13 more
doaj +1 more source