Results 21 to 30 of about 11,459 (235)
Hfq: the flexible RNA matchmaker [PDF]
Current Opinion in Microbiology, 2016 The RNA chaperone protein Hfq is critical to the function of small, base pairing RNAs in many bacteria. In the past few years, structures and modeling of wild type Hfq and assays of various mutants have documented that the homohexameric Hfq ring can contact RNA at four sites (proximal face, distal face, rim and C-terminal tail) and that different RNAs ...
Taylor B Updegrove +2 more
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Hfq is a global regulator that controls the pathogenicity of Staphylococcus aureus. [PDF]
PLoS ONE, 2010 The Hfq protein is reported to be an RNA chaperone, which is involved in the stress response and the virulence of several pathogens. In E. coli, Hfq can mediate the interaction between some sRNAs and their target mRNAs.
Yu Liu +7 more
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eLife, 2021 RNA-binding proteins play myriad roles in regulating RNAs and RNA-mediated functions. In bacteria, the RNA chaperone Hfq is an important post-transcriptional gene regulator.
Seongjin Park +8 more
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Microorganisms, 2021 Yersinia ruckeri causes outbreaks of enteric redmouth disease in salmon aquaculture all over the world. The transient antibiotic tolerance exhibited by bacterial persisters is commonly thought to be responsible for outbreaks; however, the molecular ...
Iván L. Calderón +5 more
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Hfq and its constellation of RNA [PDF]
Nature Reviews Microbiology, 2011 Hfq is an RNA-binding protein that is common to diverse bacterial lineages and has key roles in the control of gene expression. By facilitating the pairing of small RNAs with their target mRNAs, Hfq affects the translation and turnover rates of specific transcripts and contributes to complex post-transcriptional networks.
Ben F. Luisi, Jörg Vogel
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Journal of Molecular Biology, 2012 Hfq is a bacterial RNA binding protein that facilitates small RNA-mediated posttranscriptional gene regulation. In Vibrio cholerae, Hfq and four Hfq-dependent small RNAs are essential for the expression of virulence genes, but little is known about this mechanism at the molecular level. To better understand V.
Helen A. Vincent +9 more
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Profound impact of Hfq on nutrient acquisition, metabolism and motility in the plant pathogen Agrobacterium tumefaciens. [PDF]
PLoS ONE, 2014 As matchmaker between mRNA and sRNA interactions, the RNA chaperone Hfq plays a key role in riboregulation of many bacteria. Often, the global influence of Hfq on the transcriptome is reflected by substantially altered proteomes and pleiotropic ...
Philip Möller +6 more
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Overexpression of an outer membrane protein associated with decreased susceptibility to carbapenems in Proteus mirabilis. [PDF]
PLoS ONE, 2015 Proteus mirabilis isolates commonly have decreased susceptibility to imipenem. Previously, we found P. mirabilis hfq mutant was more resistant to imipenem and an outer membrane protein (OMP) could be involved.
Yi-Lin Tsai +6 more
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Effects of Hfq on the conformation and compaction of DNA [PDF]
Nucleic Acids Research, 2015 Hfq is a bacterial pleiotropic regulator that mediates several aspects of nucleic acids metabolism. The protein notably influences translation and turnover of cellular RNAs. Although most previous contributions concentrated on Hfq's interaction with RNA, its association to DNA has also been observed in vitro and in vivo.
Johan R. C. van der Maarel +11 more
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Prediction of Hfq in actinobacteria [PDF]
, 2015 AbstractHfq is the bacterial orthologue of the eukaryotic (L)Sm family of proteins found across all domains of life and potentially an ancient protein, but it has not been found in all phyletic lines. A careful search successfully identified a distant hfq orthologue in the cyanobacteria leaving the actinobacteria as the major phylum with no known hfq ...
Bora, Nagamani +2 more
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