Study of E. coli Hfq's RNA annealing acceleration and duplex destabilization activities using substrates with different GC-contents [PDF]
, 2012 Folding of RNA molecules into their functional three-dimensional structures is often supported by RNA chaperones, some of which can catalyse the two elementary reactions helix disruption and helix formation.
Beich-Frandsen, Mads +6 more
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RNA Biology, 2013 In all domains of life, non-coding RNAs (ncRNAs) play a central role in cellular biology. In bacteria, the systematic discovery and analysis of ncRNAs revealed a large repertoire of regulatory transcripts, which among other characteristics is responsible for the high adaptability of prokaryotes.
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Clostridium difficile Hfq can replace Escherichia coli Hfq for most of its function [PDF]
RNA, 2014 A gene for the Hfq protein is present in the majority of sequenced bacterial genomes. Its characteristic hexameric ring-like core structure is formed by the highly conserved N-terminal regions. In contrast, the C-terminal forms an extension, which varies in length, lacks homology, and is predicted to be unstructured.
J., Caillet +3 more
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Hfq Globally Binds and Destabilizes sRNAs and mRNAs in
mSystems, 2019 Hfq is a ubiquitous Sm-like RNA-binding protein in bacteria involved in physiological fitness and pathogenesis, while its in vivo binding nature remains elusive. Here we reported genome-wide Hfq-bound RNAs in Yersinia pestis, a causative agent of plague,
Yanping Han +7 more
doaj +1 more source
Solution heat treatment, forming and in-die quenching of a commercial sheet magnesium alloy into a complex-shaped component: experimentation and FE analysis [PDF]
, 2014 Interest in lightweight materials, particularly magnesium alloys, has increased significantly with rising efficiency requirements in the automotive sector.
Balint, D +8 more
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mBio, 2017 Legionella pneumophila is an environmental bacterium that parasitizes protozoa, but it may also infect humans, thereby causing a severe pneumonia called Legionnaires’ disease. To cycle between the environment and a eukaryotic host, L.
Giulia Oliva +4 more
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Impact of Hfq on global gene expression and intracellular survival in Brucella melitensis. [PDF]
PLoS ONE, 2013 Brucella melitensis is a facultative intracellular bacterium that replicates within macrophages. The ability of brucellae to survive and multiply in the hostile environment of host macrophages is essential to its virulence. The RNA-binding protein Hfq is
Mingquan Cui +17 more
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Adaptive remodeling of the bacterial proteome by specific ribosomal modification regulates Pseudomonas infection and niche colonisation [PDF]
, 2016 Post-transcriptional control of protein abundance is a highly important, underexplored regulatory process by which organisms respond to their environments.
A Brencic +83 more
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The RNA chaperone Hfq is important for growth and stress tolerance in Francisella novicida.
PLoS ONE, 2011 The RNA-binding protein Hfq is recognized as an important regulatory factor in a variety of cellular processes, including stress resistance and pathogenesis.
Jacob R Chambers, Kelly S Bender
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Riboregulators and the role of Hfq in photosynthetic bacteria [PDF]
RNA Biology, 2014 Anoxygenic and oxygenic bacteria directly convert solar energy into biomass using photosynthesis. The formation and composition of photosynthetic complexes has to be tightly controlled in response to environmental conditions, as exposure to sunlight can be harmful due to the generation of reactive oxygen species and the damaging effects of UV ...
Hess, Wolfgang +4 more
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