Hfq stimulates the activity of the CCA-adding enzyme [PDF]
BMC Molecular Biology, 2007 Abstract Background The bacterial Sm-like protein Hfq is known as an important regulator involved in many reactions of RNA metabolism. A prominent function of Hfq is the stimulation of RNA polyadenylation catalyzed by E. coli poly(A) polymerase I (PAP).
Scheibe, M. +4 more
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Riboregulators and the role of Hfq in photosynthetic bacteria [PDF]
RNA Biology, 2014 Anoxygenic and oxygenic bacteria directly convert solar energy into biomass using photosynthesis. The formation and composition of photosynthetic complexes has to be tightly controlled in response to environmental conditions, as exposure to sunlight can be harmful due to the generation of reactive oxygen species and the damaging effects of UV ...
Hess, Wolfgang +4 more
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Apomorphine Targets the Pleiotropic Bacterial Regulator Hfq [PDF]
Antibiotics, 2021 Hfq is a bacterial regulator with key roles in gene expression. The protein notably regulates translation efficiency and RNA decay in Gram-negative bacteria, thanks to its binding to small regulatory noncoding RNAs. This property is of primary importance for bacterial adaptation and survival in hosts.
Frank Wien +7 more
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Solution heat treatment, forming and in-die quenching of a commercial sheet magnesium alloy into a complex-shaped component: experimentation and FE analysis [PDF]
, 2014 Interest in lightweight materials, particularly magnesium alloys, has increased significantly with rising efficiency requirements in the automotive sector.
Balint, D +8 more
core +1 more source
The Hfq regulon of Neisseria meningitidis
FEBS Open Bio, 2017 The conserved RNA‐binding protein, Hfq, has multiple regulatory roles within the prokaryotic cell, including promoting stable duplex formation between small RNAs and mRNAs, and thus hfq deletion mutants have pleiotropic phenotypes. Previous proteome and transcriptome studies of Neisseria meningitidis have generated limited insight into differential ...
Robert A. G. Huis in ‘t Veld +4 more
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Models of Hfq interactions with small non-coding RNA in Gram-negative and Gram-positive bacteria
Frontiers in Cellular and Infection Microbiology, 2023 Hfq is required by many Gram-negative bacteria to chaperone the interaction between small non-coding RNA (sRNA) and mRNA to facilitate annealing. Conversely and despite the presence of Hfq in many Gram-positive bacteria, sRNAs in Gram-positive bacteria ...
Derrick Watkins, Dev Arya
doaj +1 more source
CRP-cAMP mediates silencing of Salmonella virulence at the post-transcriptional level [PDF]
, 2018 Invasion of epithelial cells by Salmonella enterica requires expression of genes located in the pathogenicity island I (SPI-1). The expression of SPI-1 genes is very tightly regulated and activated only under specific conditions.
Balsalobre, Carlos +6 more
core +4 more sources
The metabolic enzyme AdhE controls the virulence of Escherichia coli O157:H7 [PDF]
, 2014 Classical studies have focused on the role that individual regulators play in controlling virulence gene expression. An emerging theme, however, is that bacterial metabolism also plays a key role in this process.
Abernathy +59 more
core +2 more sources
Effects of Hfq on the Conformation and Compaction of DNA [PDF]
Biophysical Journal, 2016 Hfq is a bacterial pleiotropic regulator that mediates several aspects of nucleic acids metabolism. The protein notably influences translation and turnover of cellular RNAs. Although most previous contributions concentrated on Hfq's interaction with RNA, its association to DNA has also been observed in vitro and in vivo.
Johan R. C. van der Maarel +3 more
openaire +2 more sources
Post-transcriptional regulator Hfq binds catalase HPII: crystal structure of the complex. [PDF]
PLoS ONE, 2013 We report a crystal structure of Hfq and catalase HPII from Escherichia coli. The post-transcriptional regulator Hfq plays a key role in the survival of bacteria under stress.
Koji Yonekura +5 more
doaj +1 more source