Results 51 to 60 of about 11,459 (235)

The Pleiotropic Phenotypes Caused by an hfq Null Mutation in Vibrio harveyi

Microorganisms, 2023
Hfq is a global regulator and can be involved in multiple cellular processes by assisting small regulatory RNAs (sRNAs) to target mRNAs. To gain insight into the virulence regulation of Hfq in Vibrio harveyi, the hfq null mutant, ∆hfq, was constructed in
Yiqin Deng, Shujun Zang, Ziyang Lin, Liwen Xu, Changhong Cheng, Juan Feng   +5 more
doaj   +1 more source

Adaptive remodeling of the bacterial proteome by specific ribosomal modification regulates Pseudomonas infection and niche colonisation [PDF]

, 2016
Post-transcriptional control of protein abundance is a highly important, underexplored regulatory process by which organisms respond to their environments.
A Brencic, A Rico, A Shevchenko, A Zhang, AJ Spiers, Alexandra M. Howat, BL Schneider, BR Borlee, BR Kulasekara, C Lamb, C Pesavento, C Reimmann, CD Boyd, Christopher S Hayes, CO Dimkpa, D Haas, D Yu, DC Naseby, DN Rodriguez-Navarro, E Barahona, E Barahona, E Burrowes, E Trampari, Eleftheria Trampari, F Harrison, G Desnoyers, G Mulley, G Zhao, Gerhard Saalbach, GL Winsor, H Kulasakara, I Kuiper, I Moll, J Boch, J Timmermans, JA Moscoso, JA Vizcaino, Jacob G. Malone, JG Malone, JH Miller, JT Greenberg, JW Hickman, K Kino, K Lapouge, K Maki, K Matsumoto, K Potrykus, KH Choi, KK Swinger, Lucia Grenga, M Christen, M Frederix, M Gao, M Jozefczak, M Lindeberg, M Starkey, MC Whalen, MH Rau, MV Nesterchuk, MW Silby, NM Wilf, P Sobrero, R Hengge, R Little, Richard H. Little, RP Ryan, S Heeb, S Lindenberg, Sebastian Pfeilmeier, SL Kuchma, T Afonyushkin, T Moller, T Morita, TS Walker, TT Hoang, TW Lynch, U Jenal, UA Bommer, VK Ramachandran, WC Winkler, WK Kang, WM Konyecsni, XF Xin, Y Irie   +83 more
core   +3 more sources

Central role for RNase YbeY in Hfq-dependent and Hfq-independent small-RNA regulation in bacteria [PDF]

BMC Genomics, 2014
Conceptual parallels exist between bacterial and eukaryotic small-RNA (sRNA) pathways, yet relatively little is known about which protein may recognize and recruit bacterial sRNAs to interact with targets. In eukaryotes, Argonaute (AGO) proteins discharge such functions.
Diogo M. Camacho, Jonathan A. Winkler, Shree P. Pandey, Hu Li, Hu Li, Graham C. Walker, James J. Collins   +6 more
openaire   +5 more sources

The Pseudomonas aeruginosa CrcZ RNA interferes with Hfq-mediated riboregulation.

PLoS ONE, 2017
The RNA chaperone Hfq regulates virulence and metabolism in the opportunistic pathogen Pseudomonas aeruginosa. During carbon catabolite repression (CCR) Hfq together with the catabolite repression control protein Crc can act as a translational repressor ...
Elisabeth Sonnleitner, Konstantin Prindl, Udo Bläsi   +2 more
doaj   +1 more source

Lsm proteins and Hfq [PDF]

RNA Biology, 2013
The bacterial Hfq protein is a versatile modulator of RNA function and is particularly important for regulation mediated by small non-coding RNAs. Hfq is a bacterial Sm protein but bears more similarity to the eukaryotic Sm-like (Lsm) family of proteins than the prototypical Sm proteins.
Jeffrey Wilusz, Carol J. Wilusz
openaire   +3 more sources

Discovery Of Ethanol-Responsive Small Rnas In Zymomonas Mobilis [PDF]

, 2014
Zymomonas mobilis is a bacterium that can produce ethanol by fermentation. Due to its unique metabolism and efficient ethanol production, Z. mobilis has attracted special interest for biofuel energy applications; an important area of study is the ...
Cho, Seung Hee, Contreras, Lydia M., Henninger, Trey D., Lei, Roy   +3 more
core   +1 more source

Amyloid-like Hfq interaction with single-stranded DNA: involvement in recombination and replication in Escherichia coli

QRB Discovery, 2022
Interactions between proteins and single-stranded DNA (ssDNA) are crucial for many fundamental biological processes, including DNA replication and genetic recombination.
Krzysztof Kubiak, Frank Wien, Indresh Yadav, Nykola C. Jones, Søren Vrønning Hoffmann, Eric Le Cam, Antoine Cossa, Frederic Geinguenaud, Johan R. C. van der Maarel, Grzegorz Węgrzyn, Véronique Arluison   +10 more
doaj   +1 more source

The Hfq chaperone helps the ribosome mature [PDF]

The EMBO Journal, 2018
Ribosome biogenesis is a complex process that is facilitated by a large number of assembly factors. In this issue, Andrade et al (2018) provide evidence that a widely conserved RNA chaperone, Hfq, acts as a ribosomal assembly factor in bacteria. Hfq is known to support regulation of stress response genes by small RNAs.
Indra Mani Sharma, Arthur Korman, Sarah A Woodson   +2 more
openaire   +3 more sources

Functional Characterization of Acinetobacter baumannii Lacking the RNA Chaperone Hfq

Frontiers in Microbiology, 2017
The RNA chaperone Hfq is involved in the riboregulation of diverse genes via small RNAs. Recent studies have demonstrated that Hfq contributes to the stress response and the virulence of several pathogens, and the roles of Hfq vary among bacterial ...
Han-Yueh Kuo, Han-Yueh Kuo, Hsuan-Hao Chao, Po-Cheng Liao, Long Hsu, Kai-Chih Chang, Chi-Hua Tung, Chang-Hua Chen, Chang-Hua Chen, Ming-Li Liou   +9 more
doaj   +1 more source

Hfq C-terminal region forms a β-rich amyloid-like motif without perturbing the N-terminal Sm-like structure

Communications Biology, 2023
Hfq is a pleitropic actor that serves as stress response and virulence factor in the bacterial cell. To execute its multiple functions, Hfq assembles into symmetric torus-shaped hexamers.
Mélanie Berbon, Denis Martinez, Estelle Morvan, Axelle Grélard, Brice Kauffmann, Jehan Waeytens, Frank Wien, Véronique Arluison, Birgit Habenstein   +8 more
doaj   +1 more source