Results 51 to 60 of about 5,373 (162)
We show deletion of an IS200‐encoded sRNA (5′tnpA) in Salmonella impacts the expression of SPI‐1, flagellar, cysteine, and phsABC regulons. Evidence is presented that, with regard to the SPI‐1 regulon, 5′tnpA may function through base pairing with another sRNA known to regulate SPI1 called PinT.
Ryan S. Trussler +7 more
wiley +1 more source
Hfq regulates the expression of the thermostable direct hemolysin gene in
Background The hfq gene is conserved in a wide variety of bacteria and Hfq is involved in many cellular functions such as stress responses and the regulation of gene expression.
Mawatari Kazuaki +5 more
doaj +1 more source
Mechanisms and Pathological Significance of Liquid–Liquid Phase Separation in Bacteria
LLPS in bacterial infections. In biological systems, the molecular mechanisms underlying LLPS are primarily driven by multivalent protein–protein interactions, protein‐nucleic acid interactions, and intramolecular interactions mediated by IDR. Through LLPS, proteins form condensates that function as ‘microfactories,’ playing crucial roles in regulating
Yanxiao Zhao +5 more
wiley +1 more source
Dynamic Refolding of OxyS sRNA by the Hfq RNA Chaperone [PDF]
Huahuan Cai +3 more
openalex +1 more source
Process optimisation and robustness analysis for HFQ process [PDF]
Mohamed Mohamed +6 more
openalex +1 more source
ABSTRACT Xylella fastidiosa (Xf) is a Gram‐negative bacterial plant pathogen responsible for severe diseases in a variety of economically important crops. A critical aspect of its virulence is the production of extracellular vesicles (EVs). In this study, we discovered that DNA‐binding proteins and nonribosomal RNA‐binding proteins are abundant in the ...
Alessa Ruf +9 more
wiley +1 more source
Pervasive Targeting of Nascent Transcripts by Hfq
Summary: Hfq is an RNA chaperone and an important post-transcriptional regulator in bacteria. Using chromatin immunoprecipitation coupled with high-throughput DNA sequencing (ChIP-seq), we show that Hfq associates with hundreds of different regions of ...
Tracy K. Kambara +2 more
doaj +1 more source
Non‐conserved microRNAs and their roles in plants: the case for legumes
Non‐conserved miRNAs are functional and modulate stress and microbial interactions in legumes, hinting at broader roles in plant gene regulation. Abstract Several classes of small RNAs function to regulate stress and development pathways in all kingdoms of life.
Y. Hernández +3 more
wiley +1 more source
To successfully infect plant hosts, the collective regulation of virulence factors in a bacterial pathogen is crucial. Hfq is an RNA chaperone protein that facilitates the small RNA (sRNA) regulation of global gene expression at the post-transcriptional ...
Gi Yoon Shin +7 more
doaj +1 more source
Distinctive Regulation of Carbapenem Susceptibility in Pseudomonas aeruginosa by Hfq
Carbapenems are often the antibiotics of choice to combat life threatening infections caused by the opportunistic human pathogen Pseudomonas aeruginosa. The outer membrane porins OprD and OpdP serve as entry ports for carbapenems.
Elisabeth Sonnleitner +4 more
doaj +1 more source

