Results 51 to 60 of about 5,373 (162)

A Small RNA Derived From the 5′ End of the IS200 tnpA Transcript Regulates Multiple Virulence Regulons in Salmonella typhimurium

open access: yesMolecular Microbiology, Volume 124, Issue 5, Page 413-432, November 2025.
We show deletion of an IS200‐encoded sRNA (5′tnpA) in Salmonella impacts the expression of SPI‐1, flagellar, cysteine, and phsABC regulons. Evidence is presented that, with regard to the SPI‐1 regulon, 5′tnpA may function through base pairing with another sRNA known to regulate SPI1 called PinT.
Ryan S. Trussler   +7 more
wiley   +1 more source

Hfq regulates the expression of the thermostable direct hemolysin gene in Vibrio parahaemolyticus

open access: yesBMC Microbiology, 2008
Background The hfq gene is conserved in a wide variety of bacteria and Hfq is involved in many cellular functions such as stress responses and the regulation of gene expression.
Mawatari Kazuaki   +5 more
doaj   +1 more source

Mechanisms and Pathological Significance of Liquid–Liquid Phase Separation in Bacteria

open access: yesThe FASEB Journal, Volume 39, Issue 18, 30 September 2025.
LLPS in bacterial infections. In biological systems, the molecular mechanisms underlying LLPS are primarily driven by multivalent protein–protein interactions, protein‐nucleic acid interactions, and intramolecular interactions mediated by IDR. Through LLPS, proteins form condensates that function as ‘microfactories,’ playing crucial roles in regulating
Yanxiao Zhao   +5 more
wiley   +1 more source

Dynamic Refolding of OxyS sRNA by the Hfq RNA Chaperone [PDF]

open access: green, 2022
Huahuan Cai   +3 more
openalex   +1 more source

Process optimisation and robustness analysis for HFQ process [PDF]

open access: diamond, 2023
Mohamed Mohamed   +6 more
openalex   +1 more source

Extracellular Vesicles From Xylella fastidiosa Carry sRNAs and Genomic Islands, Suggesting Roles in Recipient Cells

open access: yesJournal of Extracellular Vesicles, Volume 14, Issue 6, June 2025.
ABSTRACT Xylella fastidiosa (Xf) is a Gram‐negative bacterial plant pathogen responsible for severe diseases in a variety of economically important crops. A critical aspect of its virulence is the production of extracellular vesicles (EVs). In this study, we discovered that DNA‐binding proteins and nonribosomal RNA‐binding proteins are abundant in the ...
Alessa Ruf   +9 more
wiley   +1 more source

Pervasive Targeting of Nascent Transcripts by Hfq

open access: yesCell Reports, 2018
Summary: Hfq is an RNA chaperone and an important post-transcriptional regulator in bacteria. Using chromatin immunoprecipitation coupled with high-throughput DNA sequencing (ChIP-seq), we show that Hfq associates with hundreds of different regions of ...
Tracy K. Kambara   +2 more
doaj   +1 more source

Non‐conserved microRNAs and their roles in plants: the case for legumes

open access: yesPlant Biology, Volume 27, Issue 4, Page 450-460, June 2025.
Non‐conserved miRNAs are functional and modulate stress and microbial interactions in legumes, hinting at broader roles in plant gene regulation. Abstract Several classes of small RNAs function to regulate stress and development pathways in all kingdoms of life.
Y. Hernández   +3 more
wiley   +1 more source

Functional Characterization of a Global Virulence Regulator Hfq and Identification of Hfq-Dependent sRNAs in the Plant Pathogen Pantoea ananatis

open access: yesFrontiers in Microbiology, 2019
To successfully infect plant hosts, the collective regulation of virulence factors in a bacterial pathogen is crucial. Hfq is an RNA chaperone protein that facilitates the small RNA (sRNA) regulation of global gene expression at the post-transcriptional ...
Gi Yoon Shin   +7 more
doaj   +1 more source

Distinctive Regulation of Carbapenem Susceptibility in Pseudomonas aeruginosa by Hfq

open access: yesFrontiers in Microbiology, 2020
Carbapenems are often the antibiotics of choice to combat life threatening infections caused by the opportunistic human pathogen Pseudomonas aeruginosa. The outer membrane porins OprD and OpdP serve as entry ports for carbapenems.
Elisabeth Sonnleitner   +4 more
doaj   +1 more source

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