Results 61 to 70 of about 11,459 (235)

The hyperfine structure of highly charged $^{238}_{92}$U ions with rotationally excited nuclei [PDF]

, 1999
The hyperfine structure (hfs) of electron levels of $^{238}_{92}$U ions with the nucleus excited in the low-lying rotational $2^+$ state with an energy $E_{2^+} = 44.91$ keV is investigated.
Labzowsky, L. N., Liesen, D., Nefiodov, A. V., Plunien, G., Soff, G.   +4 more
core   +2 more sources

Biological and transcriptomic studies reveal hfq is required for swimming, biofilm formation and stress response in Xanthomonas axonpodis pv. citri

BMC Microbiology, 2019
Background Hfq is a widely conserved bacterial RNA-binding protein which generally mediates the global regulatory activities involv ed in physiological process and virulence.
Xuelu Liu, Yuping Yan, Haodi Wu, Changyong Zhou, Xuefeng Wang   +4 more
doaj   +1 more source

Identifying and characterizing Hfq–RNA interactions [PDF]

Methods, 2013
To regulate stress responses and virulence, bacteria use small regulatory RNAs (sRNAs). These RNAs can up or down regulate target mRNAs through base pairing by influencing ribosomal access and RNA decay. A large class of these sRNAs, called trans-encoded sRNAs, requires the RNA binding protein Hfq to facilitate base pairing between the regulatory RNA ...
Andrew L. Feig, M.A. Faner
openaire   +3 more sources

Hfq mutation confers increased cephalosporin resistance in Klebsiella pneumoniae [PDF]

Archives of Biological Sciences, 2017
Klebsiella pneumoniae (K. pneumoniae), is an opportunistic pathogen raising significant public health concerns owing to its multi-drug resistance. Hfq, one of the main RNA-binding proteins, is a key post-transcriptional regulator.
Li Xinran, Yang Mingjuan, Ke Yuehua, Liu Mingyuan, Wang Yufei, Liu Shiwei, Bo Liu, Chen Zeliang   +7 more
doaj   +1 more source

Shewanella oneidensis Hfq promotes exponential phase growth, stationary phase culture density, and cell survival

BMC Microbiology, 2013
Background Hfq is an RNA chaperone protein that has been broadly implicated in sRNA function in bacteria. Here we describe the construction and characterization of a null allele of the gene that encodes the RNA chaperone Hfq in Shewanella oneidensis ...
Brennan Christopher M, Keane Meghan L, Hunt Taylor M, Goulet Matthew T, Mazzucca Nicholas Q, Sexton Zachary, Mezoian Taylor, Douglas Katherine E, Osborn Jessica M, Pellock Brett J   +9 more
doaj   +1 more source

Identification of small RNAs abundant in Burkholderia cenocepacia biofilms reveal putative regulators with a potential role in carbon and iron metabolism [PDF]

, 2017
Small RNAs play a regulatory role in many central metabolic processes of bacteria, as well as in developmental processes such as biofilm formation. Small RNAs of Burkholderia cenocepacia, an opportunistic pathogenic beta-proteobacterium, are to date not ...
Coenye, Tom, Kiekens, Sanne, Sass, Andrea   +2 more
core   +3 more sources

An unexpected co-crystal structure of the calpain PEF(S) domain with Hfq reveals a potential chaperone function of Hfq [PDF]

Acta Crystallographica Section F Structural Biology Communications, 2020
Calpain is a Ca2+-activated, heterodimeric cysteine protease consisting of a large catalytic subunit and a small regulatory subunit. Dysregulation of this enzyme is involved in a range of pathological conditions such as cancer, Alzheimer's disease and rheumatoid arthritis, and thus calpain I is a drug target with potential therapeutic applications ...
Joel Cresser-Brown, Christian Roth, Rudolf Konrad Allemann, Yi Jin, Pierre J. Rizkallah, David James Miller   +5 more
openaire   +4 more sources

Regulation of virulence in Francisella tularensis by small non-coding RNAs [PDF]

, 2011
Using a cDNA cloning and sequencing approach we have shown that Francisella tularensis expresses homologues of several small RNAs (sRNAs) that are well-conserved among diverse bacteria.
Alain Charbit, Eric Frapy, Guillaume Postic, Iharilalao Dubail, Jonathan Livny, Karin L. Meibom, Marion Dupuis   +6 more
core   +2 more sources

Structures of the pleiotropic translational regulator Hfq and an Hfq-RNA complex: a bacterial Sm-like protein [PDF]

The EMBO Journal, 2002
In prokaryotes, Hfq regulates translation by modulating the structure of numerous RNA molecules by binding preferentially to A/U-rich sequences. To elucidate the mechanisms of target recognition and translation regulation by Hfq, we determined the crystal structures of the Staphylococcus aureus Hfq and an Hfq-RNA complex to 1.55 and 2.71 A resolution ...
Schumacher, M.A., Pearson, R.F., Møller, T., Valentin-Hansen, P., Brennan, R.G.   +4 more
openaire   +4 more sources

Regulation of fixLJ by Hfq Controls Symbiotically Important Genes in Sinorhizobium meliloti

Molecular Plant-Microbe Interactions, 2016
The RNA-binding chaperone Hfq plays critical roles in the establishment and functionality of the symbiosis between Sinorhizobium meliloti and its legume hosts. A mutation in hfq reduces symbiotic efficiency resulting in a Fix− phenotype, characterized by
Mengsheng Gao, Hahn Nguyen, Isai Salas González, Max Teplitski   +3 more
doaj   +1 more source