Results 61 to 70 of about 5,373 (162)

The Quorum Sensing Regulated sRNA Lrs1 Is Involved in the Adaptation to Low Iron in Pseudomonas aeruginosa

Environmental Microbiology Reports, Volume 17, Issue 2, April 2025.
The quorum sensing regulated sRNA Lrs1 participates in the adaptation of Pseudomonas aeruginosa in low iron by downregulating the siderophore pyochelin, the Quorum Sensing system PQS, and its associated virulence factor phenazines. ABSTRACT Iron is an essential nutrient for microbial growth. The opportunistic pathogen Pseudomonas aeruginosa can survive
Dimitra Panagiotopoulou, Natalia Romo Catalán, Max Wilcox, Nigel Halliday, Paolo Pantalone, James Lazenby, Miguel Cámara, Stephan Heeb   +7 more
wiley   +1 more source

Deletion of the small RNA chaperone protein Hfq down regulates genes related to virulence and confers protection against wild-type Brucella challenge in mice

Frontiers in Microbiology, 2016
Brucellosis is one of the most common zoonotic epidemics worldwide. Brucella, the etiological pathogen of brucellosis, has unique virulence characteristics, including the ability to survive within the host cell.
Shuangshuang eLei, Zhijun eZhong, Yuehua eKe, Mingjuan eYang, Xiaoyang eXu, Hang eRen, Chang eAn, Jiuyun eYuan, Jiuxuan eYu, Jie eXu, Yanchun eShi, Yefeng eQiu, Yufei eWang, Guangneng ePeng, Zeliang eChen, Zeliang eChen   +15 more
doaj   +1 more source

Identification, characterization and classification of prokaryotic nucleoid‐associated proteins

Molecular Microbiology, Volume 123, Issue 3, Page 206-217, March 2025.
Nucleoid‐associated proteins (NAPs) structure DNA by either bending, wrapping, bridging, or forming protein filaments on the DNA. We review newly identified NAPs and provide a list of simple biochemical assays to study the DNA‐structuring properties of novel NAPs. Abstract Common throughout life is the need to compact and organize the genome.
Samuel Schwab, Remus T. Dame
wiley   +1 more source

The RNA chaperone Hfq has a multifaceted role in Edwardsiella ictaluri

Frontiers in Cellular and Infection Microbiology
Edwardsiella ictaluri is a Gram-negative, facultative intracellular bacterium that causes enteric septicemia in catfish (ESC). The RNA chaperone Hfq (host factor for phage Qβ replication) facilitates gene regulation via small RNAs (sRNAs) in various ...
Ali Akgul, Safak Kalindamar, Adef O. Kordon, Hossam Abdelhamed, Iman Ibrahim, Hasan C. Tekedar, Attila Karsi   +6 more
doaj   +1 more source

Conditional Hfq Association with Small Noncoding RNAs in Pseudomonas aeruginosa Revealed through Comparative UV Cross-Linking Immunoprecipitation Followed by High-Throughput Sequencing

mSystems, 2019
Bacterial small noncoding RNAs (sRNAs) play posttranscriptional regulatory roles in cellular responses to changing environmental cues and in adaptation to harsh conditions. Generally, the RNA-binding protein Hfq helps sRNAs associate with target mRNAs to
Kotaro Chihara, Thorsten Bischler, Lars Barquist, Vivian A. Monzon, Naohiro Noda, Jörg Vogel, Satoshi Tsuneda   +6 more
doaj   +1 more source

An upstream Hfq binding site in the fhlA mRNA leader region facilitates the OxyS-fhlA interaction.

PLoS ONE, 2010
BackgroundTo survive, bacteria must be able to adapt to environmental stresses. Small regulatory RNAs have been implicated as intermediates in a variety of stress-response pathways allowing dynamic gene regulation. The RNA binding protein Hfq facilitates
Nilshad N Salim, Andrew L Feig
doaj   +1 more source

Identification of RNAs bound by Hfq reveals widespread RNA partners and a sporulation regulator in the human pathogen Clostridioides difficile [PDF]

, 2021
Pierre Boudry, Emma Piattelli, Emilie Drouineau, Johann Peltier, Anaïs Boutserin, Maxence Lejars, Eliane Hajnsdorf, Marc Monot, Bruno Dupuy, Isabelle Martin‐Verstraete, Daniel Gautheret, Claire Toffano‐Nioche, Olga Soutourina   +12 more
openalex   +1 more source

Impact of Hfq on the intrinsic drug resistance of Salmonella enterica serovar Typhimurium

Frontiers in Microbiology, 2012
Salmonella enterica is an important enteric pathogen, and its various serovars cause both systemic and intestinal diseases in humans and domestic animals.
Mitsuko eHayashi-Nishino, Aiko eFukushima, Kunihiko eNishino   +2 more
doaj   +1 more source

Pleiotropic regulatory function of the RNA chaperone Hfq in the Pseudomonas protegens FD6

Phytopathology Research
The rhizosphere bacterium Pseudomonas protegens FD6, which is associated with the production of antibiotics such as pyoluteorin (PLT) and 2,4-diacetylphloroglucinol (2,4-DAPG), has strong antagonistic effects on phytopathogens.
Deyu Wen, Jieyu Hu, Ziying Gao, Chenglin Xing, Yao Xiao, Tao Wu, Xiaogang Wu, Qingxia Zhang   +7 more
doaj   +1 more source

Dynamic interactions between the RNA chaperone Hfq, small regulatory RNAs and mRNAs in live bacterial cells [PDF]

, 2020
Seong-Jin Park, Karine Prévost, Emily M. Heideman, Marie‐Claude Carrier, Matthew Reyer, Wei Liu, Éric Massé, Jingyi Fei   +7 more
openalex   +1 more source