Results 71 to 80 of about 11,806 (233)
Background Hfq is a widely conserved bacterial RNA-binding protein which generally mediates the global regulatory activities involv ed in physiological process and virulence.
Xuelu Liu +4 more
doaj +1 more source
Monopole Floer homology for rational homology 3-spheres
We give a new construction of monopole Floer homology for spin-c rational homology 3-spheres. As applications we define two invariants of certain smooth compact 4-manifolds with b_1=1 and b^+=0.Comment: 60 pages, to appear in Duke J. Math.
Froyshov, Kim A.
core +1 more source
Effect of shear stress on Pseudomonas aeruginosa isolated from the cystic fibrosis lung [PDF]
Chronic colonization of the lungs by Pseudomonas aeruginosa is one of the major causes of morbidity and mortality in cystic fibrosis (CF) patients. To gain insights into the characteristic biofilm phenotype of P. aeruginosa in the CF lungs, mimicking the
Cornelis, Pierre +7 more
core +3 more sources
Interaction of the RNA chaperone Hfq with mRNAs: direct and indirect roles of Hfq in iron metabolism of Escherichia coli [PDF]
SummaryThe Escherichia coli Sm‐like host factor I (Hfq) is thought to play direct and indirect roles in post‐transcriptional regulation by targeting small regulatory RNAs and mRNAs. In this study, we have used proteomics to identify new mRNA targets of Hfq.
Vecerek, Branislav +4 more
openaire +3 more sources
Background Hfq is an RNA chaperone protein that has been broadly implicated in sRNA function in bacteria. Here we describe the construction and characterization of a null allele of the gene that encodes the RNA chaperone Hfq in Shewanella oneidensis ...
Brennan Christopher M +9 more
doaj +1 more source
E. coli DNA associated with isolated Hfq interacts with Hfq's distal surface and C-terminal domain [PDF]
The RNA-binding protein Hfq has been studied extensively for its function as a modulator of gene expression at the post-transcriptional level. While most Hfq studies have focused on the protein's interaction with sRNAs and mRNAs, Hfq binding to DNA has been observed but is less explored.
Taylor B, Updegrove +4 more
openaire +2 more sources
The metabolic enzyme AdhE controls the virulence of Escherichia coli O157:H7 [PDF]
Classical studies have focused on the role that individual regulators play in controlling virulence gene expression. An emerging theme, however, is that bacterial metabolism also plays a key role in this process.
Abernathy +59 more
core +2 more sources
Fluorescence Reporters for Hfq Oligomerization and RNA Annealing [PDF]
Fluorescence spectroscopy is a sensitive technique for detecting protein-protein, protein-RNA, and RNA-RNA interactions, requiring only nanomolar concentrations of labeled components. Fluorescence anisotropy provides information about the assembly of multi-subunit proteins, while molecular beacons provide a sensitive and quantitative reporter for base ...
Subrata Panja, Sarah A. Woodson
openalex +3 more sources
Regulation of fixLJ by Hfq Controls Symbiotically Important Genes in Sinorhizobium meliloti
The RNA-binding chaperone Hfq plays critical roles in the establishment and functionality of the symbiosis between Sinorhizobium meliloti and its legume hosts. A mutation in hfq reduces symbiotic efficiency resulting in a Fix− phenotype, characterized by
Mengsheng Gao +3 more
doaj +1 more source
Many RNA-RNA interactions depend on molecular chaperones to form and remain stable in living cells. A prime example is the RNA chaperone Hfq, which is a critical effector involved in regulatory interactions between small RNAs (sRNAs) and cognate target ...
David Lalaouna +8 more
doaj +1 more source

