Results 81 to 90 of about 11,806 (233)
Molecular Microbiology, EarlyView.Under iron‐limited conditions, FsrA base‐pairs with the intergenic region between epeX and epeE, enhancing epeE translation and triggering EPE production. Toxin‐mediated cell lysis releases nutrients, including iron, which can be taken up by surviving cells.
Sarah Miercke +3 more
wiley +1 more source
Hfq stimulates the activity of the CCA-adding enzyme [PDF]
BMC Molecular Biology, 2007 Abstract Background The bacterial Sm-like protein Hfq is known as an important regulator involved in many reactions of RNA metabolism. A prominent function of Hfq is the stimulation of RNA polyadenylation catalyzed by E. coli poly(A) polymerase I (PAP).
Scheibe, M. +4 more
openaire +3 more sources
Structural and biochemical studies on ATP binding and hydrolysis by the Escherichia coli RNA chaperone Hfq. [PDF]
PLoS ONE, 2012 In Escherichia coli the RNA chaperone Hfq is involved in riboregulation by assisting base-pairing between small regulatory RNAs (sRNAs) and mRNA targets. Several structural and biochemical studies revealed RNA binding sites on either surface of the donut
Hermann Hämmerle +6 more
doaj +1 more source
Determination of an Interaction Network between an Extracellular Bacterial Pathogen and the Human Host [PDF]
, 2019 A major gap in understanding infectious diseases is the lack of information about molecular interaction networks between pathogens and the human host.
Barnes, Stephen +9 more
core +1 more source
Molecular Microbiology, Volume 124, Issue 5, Page 413-432, November 2025.We show deletion of an IS200‐encoded sRNA (5′tnpA) in Salmonella impacts the expression of SPI‐1, flagellar, cysteine, and phsABC regulons. Evidence is presented that, with regard to the SPI‐1 regulon, 5′tnpA may function through base pairing with another sRNA known to regulate SPI1 called PinT.
Ryan S. Trussler +7 more
wiley +1 more source
Sm‐like protein Hfq: Location of the ATP‐binding site and the effect of ATP on Hfq–RNA complexes [PDF]
Protein Science, 2007 AbstractSm‐like proteins are ubiquitous ring‐shaped oligomers that exhibit a variety of nucleic acid‐binding activities. They have been linked functionally to various cellular events involving RNA, and it is generally believed that their activity is exerted via the passive binding of nucleic acids.
Arluison, Veronique +4 more
openaire +3 more sources
Hfq proximity and orientation controls RNA annealing [PDF]
Nucleic Acids Research, 2012 Regulation of bacterial gene networks by small non-coding RNAs (sRNAs) requires base pairing with messenger RNA (mRNA) targets, which is facilitated by Hfq protein. Hfq is recruited to sRNAs and mRNAs through U-rich- and A-rich-binding sites, respectively, but their distance from the sRNA-mRNA complementary region varies widely among different genes ...
Panja, Subrata, Woodson, Sarah A.
openaire +2 more sources
Comprehensive Reviews in Food Science and Food Safety, Volume 24, Issue 5, September 2025.ABSTRACT Listeria monocytogenes is a foodborne pathogen that poses significant challenges to food safety and public health due to its ability to adapt to harsh environments, particularly those found in food processing facilities. This review explores the global transcriptional responses of L.
Nagendran Rajalingam, Sam Van Haute
wiley +1 more source
Hfq variant with altered RNA binding functions [PDF]
Nucleic Acids Research, 2006 The interaction between Hfq and RNA is central to multiple regulatory processes. Using site-directed mutagenesis, we have found a missense mutation in Hfq (V43R) which strongly affects2 the RNA binding capacity of the Hfq protein and its ability to stimulate poly(A) tail elongation by poly(A)-polymerase in vitro.
Ziolkowska, K. +6 more
openaire +3 more sources
Hfq regulates the expression of the thermostable direct hemolysin gene in
BMC Microbiology, 2008 Background The hfq gene is conserved in a wide variety of bacteria and Hfq is involved in many cellular functions such as stress responses and the regulation of gene expression.
Mawatari Kazuaki +5 more
doaj +1 more source