Results 71 to 80 of about 13,098 (176)
F1000Research, 2017 In 2004, when the protein estimate from the finished human genome was only 24,000, the surprise was compounded as reviewed estimates fell to 19,000 by 2014. However, variability in the total canonical protein counts (i.e.
Christopher Southan
doaj +1 more source
Reproducible probe-level analysis of the Affymetrix Exon 1.0 ST array with R/Bioconductor
, 2013 The presence of different transcripts of a gene across samples can be analysed by whole-transcriptome microarrays. Reproducing results from published microarray data represents a challenge due to the vast amounts of data and the large variety of pre ...
Bødker, Julie Støve +7 more
core +1 more source
Proteomic Changes in Cancer Cell Lines as a Result of Bacterial Infection
PROTEOMICS, EarlyView.ABSTRACT Bacterial infections have been implicated in shaping the tumor microenvironment (TME), but their effects on cancer cell proteomes remain unexplored. In this study, we analyzed proteomic changes in melanoma (A375) and ovarian cancer (OVCAR3) cell line models following infection with Staphylococcus aureus strain USA300 or Salmonella enterica ...
Bo Ren +7 more
wiley +1 more source
, 2020 The mitochondrial cytochrome c oxidase, the terminal enzyme of the respiratory chain, contains heme and copper centers for electron transfer. The conserved COX2 subunit contains the CuA site, a binuclear copper center.
Aich, A. +11 more
core +2 more sources
Genomic convergence and network analysis approach to identify candidate genes in Alzheimer's disease [PDF]
, 2014 BACKGROUND: Alzheimer’s disease (AD) is one of the leading genetically complex and heterogeneous disorder that is influenced by both genetic and environmental factors. The underlying risk factors remain largely unclear for this heterogeneous disorder. In
Meenal Gupta +6 more
core +1 more source
Cancer Hallmarks Expression in Oral Leukoplakia: Systematic Review and Meta‐Analysis
Oral Diseases, EarlyView.ABSTRACT Objectives To assess the available evidence on the expression of hallmarks of cancer and oral leukoplakia (OL) malignant transformation probability, with the goal of identifying the earliest oncogenic molecular events participating in oral cancer carcinogenesis.
I. González‐Ruiz +4 more
wiley +1 more source
DNF Sampling for ProbLog Inference [PDF]
, 2010 Inference in probabilistic logic languages such as ProbLog, an extension of Prolog with probabilistic facts, is often based on a reduction to a propositional formula in DNF. Calculating the probability of such a formula involves the disjoint-sum-problem,
Janssens, Gerda +3 more
core
PhD-SNPg: a webserver and lightweight tool for scoring single nucleotide variants [PDF]
, 2017 One of the major challenges in human genetics is to identify functional effects of coding and non-coding single nucleotide variants (SNVs). In the past, several methods have been developed to identify disease-related single amino acid changes but only ...
Capriotti, Emidio, Fariselli, Piero
core +3 more sources
American Journal of Medical Genetics Part A, Volume 200, Issue 2, Page 291-299, February 2026.ABSTRACT Heterozygous pathogenic variants in TBX3 cause Ulnar‐Mammary syndrome (UMS). The phenotype is classically characterized by upper limb defects, apocrine/mammary gland hypoplasia, hypogonadism, and various midline defects. However, the clinical spectrum is highly variable, and some individuals may present with a mild or atypical presentation ...
Ziv Halperin, Karin Weiss
wiley +1 more source
ING4 (inhibitor of growth family, member 4) [PDF]
, 2011 Review on ING4 (inhibitor of growth family, member 4), with data on DNA, on the protein encoded, and where the gene is ...
Greco, A, Miranda, C
core +1 more source