Results 51 to 60 of about 2,707 (196)

Evaluation of TURP specimen with special reference to prostatic intraepithelial neoplasia and prostatic cancer using light microscopy and immunohistochemical markers of P63, CK5/6, AMACR (p504s), and PSA

open access: yesNational Journal of Physiology, Pharmacy and Pharmacology, 2023
Background: Prostate cancer is the world's leading cause of cancer and the second cause of cancer-related death in men after lung cancer. The incidence of prostatic carcinoma is increasing with age.
Rojina Khatun   +2 more
doaj   +1 more source

Evaluation of immunoexpression and MDR1 promoter methylation levels in prostatic tissue samples [PDF]

open access: yes, 2008
Os objectivos deste estudo foram: (1) Determinar os níveis de metilação do promotor do MDR1 em tecido prostático com adenocarcinoma (CaP), neoplasia intraepitelial prostática de alto grau (HGPIN), hiperplasia benigna (BPH) e tecido morfologicamente ...
Costa, Vera L.   +5 more
core  

Targeted transperineal biopsy of the prostate has limited additional benefit over background cores for larger MRI-identified tumors. [PDF]

open access: yes, 2015
PURPOSE: To compare histological outcomes in patients undergoing MRI-transrectal ultrasound fusion transperineal (MTTP) prostate biopsy and determine the incremental benefit of targeted cores.
Barrett, Tristan   +8 more
core   +2 more sources

Synergistic Inhibition of Prostate Cancer Progression in Mice With a Combination of Curcumin and Ursolic Acid in the Diet

open access: yesMolecular Carcinogenesis, Volume 64, Issue 9, Page 1487-1499, September 2025.
ABSTRACT Prostate cancer (PCa) is the second leading cause of cancer‐related death among American men, and its long latency offers a window for chemopreventive strategies. Phytochemicals, with their diverse impacts on cancer cell growth and metabolism, represent promising candidates for such strategies.
Chelsea A. Friedman   +5 more
wiley   +1 more source

Prostate cancer detection at rebiopsy after an initial benign diagnosis: results using sextant extended prostate biopsy

open access: yesClinics, 2008
INTRODUCTION: Sextant prostate biopsy remains the standard technique for the detection of prostate cancer. It is well known that after a diagnosis of small acinar proliferation (ASAP) or high grade prostate intraepithelial neoplasia (HGPIN), the ...
Katia Ramos Moreira Leite   +5 more
doaj   +1 more source

Development and validation of risk score for predicting positive repeat prostate biopsy in patients with a previous negative biopsy in a UK population. [PDF]

open access: yes, 2011
BACKGROUND: Little evidence is available to determine which patients should undergo repeat biopsy after initial benign extended core biopsy (ECB). Attempts have been made to reduce the frequency of negative repeat biopsies using PSA kinetics, density ...
Doble, Andrew   +4 more
core  

Histopathologic Features and Transcriptomic Signatures Do Not Solve the Issue of Magnetic Resonance Imaging‐Invisible Prostate Cancers: A Matched‐Pair Analysis

open access: yesThe Prostate, Volume 85, Issue 4, Page 374-384, March 2025.
ABSTRACT Background Multiparametric magnetic resonance imaging (mpMRI) is pivotal in prostate cancer (PCa) diagnosis, but some clinically significant (cs) PCa remain undetected. This study aims to understand the pathological and molecular basis for csPCa visibility at mpMRI.
Marco Oderda   +12 more
wiley   +1 more source

A Retrospective Study on Pathologic Features and Racial Disparities in Prostate Cancer

open access: yesProstate Cancer, 2011
We reviewed more than 3,000 pathology reports on prostate cancer-related surgical specimens and analyzed racial disparities in histological and clinical features at the time of initial biopsy, diagnosis of prostate cancer, and prostatectomy, as well as ...
Steven A. Bigler   +2 more
doaj   +1 more source

The implication of initial 24-core transrectal prostate biopsy protocol on the detection of significant prostate cancer and high grade prostatic intraepithelial neoplasia

open access: yesInternational Brazilian Journal of Urology, 2011
PURPOSE: To assess the diagnostic value of an initial 24-sample transrectal ultrasound guided (TRUS) prostate biopsy protocol compared to the 10-core technique.
Michael Nomikos   +4 more
doaj   +1 more source

CCL11 (eotaxin‐1): A new diagnostic serum marker for prostate cancer [PDF]

open access: yes, 2012
BACKGROUND The recent recommendation of the U.S. Preventive Services Task Force against PSA‐based screening for prostate cancer was based, in part, on the lack of demonstrated diagnostic utility of serum PSA values in the low, but detectable range to ...
Agarwal, Manisha   +4 more
core   +1 more source

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