Sleeping Beauty screen reveals Pparg activation in metastatic prostate cancer [PDF]
Prostate cancer (CaP) is the most common adult male cancer in the developed world. The paucity of biomarkers to predict prostate tumor biology makes it important to identify key pathways that confer poor prognosis and guide potential targeted therapy ...
Adams, David J. +15 more
core +1 more source
Predicting prostate biopsy outcome: Prostate health index (phi) and prostate cancer antigen 3 (PCA3) are useful biomarkers [PDF]
Indication for prostate biopsy is presently mainly based on prostate-specific antigen (PSA) serum levels and digital-rectal examination (DRE). In view of the unsatisfactory accuracy of these two diagnostic exams, research has focused on novel markers to ...
A. D. Carlo +13 more
core +1 more source
Translationally controlled tumor protein in prostatic adenocarcinoma: correlation with tumor grading and treatment-related changes [PDF]
12Prostate cancer is the second leading cause of cancer-related death. The androgen deprivation therapy is the standard treatment for advanced stages. Unfortunately, virtually all tumors become resistant to androgen withdrawal.
Alessandro Ginori +11 more
core +3 more sources
Background Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) is an adapter protein which has been shown to play an active role in a wide variety of cellular processes, including interactions with proteins related to both tumor suppression and ...
Chandran Uma R +3 more
doaj +1 more source
Production of a soluble and functional recombinant apolipoproteinD in the Pichia pastoris expression system [PDF]
ApolipoproteinD (ApoD) is a human glycoprotein from the lipocalin family. ApoD contains a conserved central motif of an 8-stranded antiparallel β-sheet, which forms a beta-barrel that can be used for transport and storage of diverse hydrophobic ligands ...
Armanmehr, S. +2 more
core +1 more source
Detection of TMPRSS2 : ERG fusion gene in circulating prostate cancer cells [PDF]
Creative Commons Attribution-NonCommercial-Share Alike 3.0 license (CC BY-NC SA)Aim: To investigate the existence of TMPRSS2:ERG fusion gene in circulating tumor cells (CTC) from prostate cancer patients and its potential in monitoring tumor metastasis ...
Bryan D. Young +16 more
core +1 more source
ZEB1 is Negatively Correlated with E-Cadherin in Prostatic Anomaly Tissue
Background: Prostatic anomalies are common in tumor or infection condition. The enlargement of prostate gland affects the epithelial cell polarity that involves epithelial-mesenchymal transition (EMT).
Sari Eka Pratiwi +7 more
doaj +1 more source
RPS2: a novel therapeutic target in prostate cancer [PDF]
Background A number of studies have previously shown that the over expression of different ribosomal proteins might play an important role in cancer (i.e. S3a, L10, L16).
Min Wang, Youji Hu, Mark E Stearns
core +1 more source
Periacinar clefting and p63 immunostaining in prostatic intraepithelial neoplasia and prostatic carcinoma [PDF]
The aim of the present study was to correlate the presence and extent of retraction clefting and the expression of p63 in neoplastic glands and glands with prostatic intraepithelial neoplasia (PIN) in needle core biopsies.
Belicza, Mladen +5 more
core +1 more source
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +3 more sources

