Results 21 to 30 of about 2,747 (207)

Diagnostic utility of α-methylacyl CoA racemase (P504S) & HMWCK in morphologically difficult prostate cancer [PDF]

, 2010
Background To evaluate the diagnostic utility of alpha-methylacyl CoA racemase (P504S) & HMWCK (34beta E12) in morphologically difficult prostate cancer.
K Kumaresan, Nandita Kakkar, Alka Verma, Arup Mandal, Shrawan Singh, Kusum Joshi   +5 more
core   +1 more source

Activation of β‐Catenin in mouse prostate causes HGPIN and continuous prostate growth after castration [PDF]

The Prostate, 2008
AbstractBACKGROUNDThe role of Wnt/β‐Catenin signaling in embryogenesis and carcinogenesis has been extensively studied in organs such as colon, lung and pancreas, but little is known about Wnt/β‐Catenin signaling in the prostate. Although stabilizing mutations in APC and β‐Catenin are rare in primary prostate tumors, recent studies suggest that ...
Xiuping, Yu, Yongqing, Wang, Ming, Jiang, Brian, Bierie, Pradip, Roy-Burman, Michael M, Shen, Makoto Mark, Taketo, Marcia, Wills, Robert J, Matusik   +8 more
openaire   +2 more sources

High grade intraepithelial neoplasia of prostate is associated with values of prostate specific antigen related parameters intermediate between prostate cancer and normal levels

Biomolecules & Biomedicine, 2011
High grade prostatic intraepithelial neoplasia (HGPIN) is widely regarded as the precancerous. The aim of this study was to determine PSA related parameters in patients with initial PSA values 2-10 ng/mL and diagnosis of HGPIN without finding carcinoma ...
Nermina Obralic, Benjamin Kulovac
doaj   +1 more source

Overexpression of MiR-155-5p and increased number of macrophage population in precancerous prostatic disease

Health Science Journal of Indonesia, 2020
Latar Belakang: Gangguan regulasi mikroRNA(miR) dan inflamasi kronik dapat mengubah tumor menjadi karsinoma dan kanker dengan metastasis melalui perubahan seluler dan genomik. Lesi prekanker memiliki peluang 33,3 persen menjadi kanker.
Rachma Greta Putri, Sari Eka Pratiwi, Didik Setyo Heriyanto, Danarto Danarto, Indwiani Astuti, Nur Arfian, Sofia Mubarika Haryana   +6 more
doaj   +1 more source

Outcomes of prostate atypical small acinar proliferation and high-grade prostate intraepithelial neoplasm patients

Urological Science, 2018
Objective: Atypical small acinar proliferation (ASAP) and high-grade prostatic intraepithelial neoplasia (HGPIN) are two pathological findings occasionally noted in prostate biopsies.
Sheng-Yung Tung, Yeong-Shiau Pu, Chao-Yuan Huang, Hong-Chiang Chang, Kuo-How Huang, Shuo-Meng Wang, Huai-Ching Tai, Chung-Hsin Chen   +7 more
doaj   +1 more source

Interobserver Variability in the Diagnosis of High-Grade Prostatic Intraepithelial Neoplasia in a Tertiary Hospital in Northern Jordan

Clinical Pathology, 2020
Prostate intraepithelial neoplasia is described as a precursor lesion to prostatic adenocarcinoma. High-grade prostate intraepithelial neoplasia (HGPIN) is classified as both grade 2 and 3 prostate intraepithelial neoplasia due to inconsistency between ...
Najla Aldaoud, Amer Hallak, Nour Abdo, Samir Al Bashir, Noor Marji, Ashley Graboski-Bauer   +5 more
doaj   +1 more source

A Cross-Sectional Study of prevalence of Prostate lesions and inter-Observer Variability in Histopathological Reporting

Men's Health Journal, 2021
Introduction: To report the prevalence of various prostate lesions in the general population through cadaver prostates and to determine the interobserver variability for reporting high-grade lesions of the prostate.
Rachna Gulati, Neena Katoch, Sharmila Dudani, Subhendu Pandit, Manish S Ahuja   +4 more
doaj   +1 more source

Absolute quantitation of DNA methylation of 28 candidate genes in prostate cancer using pyrosequencing [PDF]

, 2011
This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Aberrant DNA methylation plays a pivotal
Beltran, L, Berney, DM, Brentnall, AR, Cuzick, J, Kim, DC, Kudahetti, SC, Lorincz, AT, Lu, YJ, Mao, XY, Shaw, GL, Thorat, MA, Vasiljevic, N, Wu, KQ, Xue, LY, Yu, YW   +14 more
core   +2 more sources

Pathogenic Intestinal Bacteria Enhance Prostate Cancer Development via Systemic Activation of Immune Cells in Mice [PDF]

, 2013
A role for microbes has been suspected in prostate cancer but difficult to confirm in human patients. We show here that a gastrointestinal (GI) tract bacterial infection is sufficient to enhance prostate intraepithelial neoplasia (PIN) and microinvasive ...
A Peled, AM De Marzo, AR Moser, Bruce H. Horwitz, Chung-Wei Lee, D Giri, Deyu Fang, E Derhovanessian, E Gounaris, F Balkwill, GA Rook, GE Steiner, GS Palapattu, H Biermann, J Folkman, James G. Fox, JE Montie, JG Fox, JG Fox, JG Fox, KC Valkenburg, Kelsey Cappelle, KJ Bruxvoort, M Royuela, Michael Doulberis, MJ Bissell, P Correa, Q Zhang, R Jabeen, S Wu, SB Shappell, SE Erdman, SE Erdman, SI Grivennikov, Susan E. Erdman, T Poutahidis, Tatiana Levkovich, Theofilos Poutahidis, TJ Jerde, VP Rao, WA Sakr, WG Nelson, WJ Chae, Zhongming Ge   +43 more
core   +11 more sources

Prognostic significance of epithelial/stromal caveolin‐1 expression in prostatic hyperplasia, high grade prostatic intraepithelial hyperplasia and prostatic carcinoma and its correlation with microvessel density

Journal of the Egyptian National Cancer Institute, 2017
Caveolin-1 may play a role in cancer development and progression. The aim was to record the expression and localization of caveolin-1 in benign prostatic hyperplasia (BPH), high grade prostatic intraepithelial neoplasia (HGPIN) and prostatic carcinoma ...
Dareen A. Mohammed, Duaa S. Helal
doaj   +1 more source