Background: To evaluate tumor-associated macrophages (TAMs) infiltration and microvessel density as possible prognostic factors related to prostate cancer (PCa) progression. Methods: Immunostaining of TAMs in prostate biopsy specimens was performed using
Prahara Yuri +2 more
doaj +1 more source
Inflammation: an important parameter in the search of prostate cancer biomarkers [PDF]
Background A more specific and early diagnostics for prostate cancer (PCa) is highly desirable. In this study, being inflammation the focus of our effort, serum protein profiles were analyzed in order to investigate if this parameter could interfere ...
BELLEI, Elisa +9 more
core +1 more source
OBJECTIVE:To assess the incidence of prostate adenocarcinoma in patients undergoing radical cystoprostatectomy due to bladder cancer in Iranian men. MATERIALS AND METHODS: Fifty cystoprostatectomy specimens removed due to bladder malignancy (2004-2005 ...
S.Y. Hosseini +6 more
doaj +1 more source
Evaluation of immunoexpression and MDR1 promoter methylation levels in prostatic tissue samples [PDF]
Os objectivos deste estudo foram: (1) Determinar os níveis de metilação do promotor do MDR1 em tecido prostático com adenocarcinoma (CaP), neoplasia intraepitelial prostática de alto grau (HGPIN), hiperplasia benigna (BPH) e tecido morfologicamente ...
Costa, Vera L. +5 more
core
Prostate cancer and the influence of dietary factors and supplements: a systematic review [PDF]
Background Prostate cancer is the second most common cause of cancer worldwide after lung cancer. There is increasing evidence that diet and lifestyle plays a crucial role in prostate cancer biology and tumourigenesis.
Mandair, D +4 more
core +2 more sources
Tailored for Real-World: A Whole Slide Image Classification System Validated on Uncurated Multi-Site Data Emulating the Prospective Pathology Workload. [PDF]
Standard of care diagnostic procedure for suspected skin cancer is microscopic examination of hematoxylin & eosin stained tissue by a pathologist. Areas of high inter-pathologist discordance and rising biopsy rates necessitate higher efficiency and ...
Ayyagari, Devi +11 more
core +1 more source
Targeted transperineal biopsy of the prostate has limited additional benefit over background cores for larger MRI-identified tumors. [PDF]
PURPOSE: To compare histological outcomes in patients undergoing MRI-transrectal ultrasound fusion transperineal (MTTP) prostate biopsy and determine the incremental benefit of targeted cores.
Barrett, Tristan +8 more
core +2 more sources
Is There a Role for Prostate Tumour Overexpressed-1 in the Diagnosis of HGPIN and of Prostatic Adenocarcinoma? A Comparison with α-Methylacyl CoA Racemase [PDF]
Prostate Tumour Overexpressed-1 (PTOV1) was recently identified as a novel gene and protein during a differential display screening for genes overexpressed in prostate cancer (PCa). α-Methyl-CoA racemose (AMACR) mRNA was identified as being overexpressed in PCa.
M, Scarpelli +6 more
openaire +2 more sources
The antigen Ki-67, which is associated with cell proliferation, has been demonstrated to be useful in predicting the development of human tumors. The objective of this study was to evaluate the prognostic utility of this biomarker in pre-malignant and ...
E Muñoz, F Gómez, JI Paz, I Casado
doaj +1 more source
Clinical significance of the De Ritis ratio for detecting prostate cancer in a repeat prostate biopsy [PDF]
Purpose: We evaluated factors predicting a positive repeat biopsy result in patients with an initial negative prostate biopsy result. Materials and Methods: This study included 124 patients in whom prostate cancer (PCa) was not detected in the initial ...
Heon Ha +11 more
doaj +1 more source

