Results 51 to 60 of about 2,747 (207)

Evaluation of TURP specimen with special reference to prostatic intraepithelial neoplasia and prostatic cancer using light microscopy and immunohistochemical markers of P63, CK5/6, AMACR (p504s), and PSA

open access: yesNational Journal of Physiology, Pharmacy and Pharmacology, 2023
Background: Prostate cancer is the world's leading cause of cancer and the second cause of cancer-related death in men after lung cancer. The incidence of prostatic carcinoma is increasing with age.
Rojina Khatun   +2 more
doaj   +1 more source

The dietary isothiocyanate sulforaphane modulates gene expression and alternative gene splicing in a PTEN null preclinical murine model of prostate cancer [PDF]

open access: yes, 2010
Background Dietary or therapeutic interventions to counteract the loss of PTEN expression could contribute to the prevention of prostate carcinogenesis or reduce the rate of cancer progression.
Maria H Traka   +6 more
core   +1 more source

Synergistic Inhibition of Prostate Cancer Progression in Mice With a Combination of Curcumin and Ursolic Acid in the Diet

open access: yesMolecular Carcinogenesis, Volume 64, Issue 9, Page 1487-1499, September 2025.
ABSTRACT Prostate cancer (PCa) is the second leading cause of cancer‐related death among American men, and its long latency offers a window for chemopreventive strategies. Phytochemicals, with their diverse impacts on cancer cell growth and metabolism, represent promising candidates for such strategies.
Chelsea A. Friedman   +5 more
wiley   +1 more source

Prostate cancer detection at rebiopsy after an initial benign diagnosis: results using sextant extended prostate biopsy

open access: yesClinics, 2008
INTRODUCTION: Sextant prostate biopsy remains the standard technique for the detection of prostate cancer. It is well known that after a diagnosis of small acinar proliferation (ASAP) or high grade prostate intraepithelial neoplasia (HGPIN), the ...
Katia Ramos Moreira Leite   +5 more
doaj   +1 more source

CCL11 (eotaxin‐1): A new diagnostic serum marker for prostate cancer [PDF]

open access: yes, 2012
BACKGROUND The recent recommendation of the U.S. Preventive Services Task Force against PSA‐based screening for prostate cancer was based, in part, on the lack of demonstrated diagnostic utility of serum PSA values in the low, but detectable range to ...
Agarwal, Manisha   +4 more
core   +1 more source

Stem-like and highly invasive prostate cancer cells expressing CD44v8-10 marker originate from CD44-negative cells [PDF]

open access: yes, 2018
In human prostate cancer (PCa), the neuroendocrine cells, expressing the prostate cancer stem cell (CSC) marker CD44, may be resistant to androgen ablation and promote tumor recurrence.
Campese, Af   +15 more
core   +2 more sources

Statin use linked with a decrease in the conversion from high-grade prostatic intraepithelial neoplasia (HGPIN) to prostate cancer [PDF]

open access: yesCarcinogenesis, 2018
The roles of obesity, metabolic dysregulation and systemic inflammation to advance prostate carcinogenesis are unclear. This study investigates metabolic and inflammatory factors in the transition from high-grade prostatic intraepithelial neoplasia (HGPIN) to prostate cancer (PC).
Jay H, Fowke, Saundra S, Motley
openaire   +2 more sources

Histopathologic Features and Transcriptomic Signatures Do Not Solve the Issue of Magnetic Resonance Imaging‐Invisible Prostate Cancers: A Matched‐Pair Analysis

open access: yesThe Prostate, Volume 85, Issue 4, Page 374-384, March 2025.
ABSTRACT Background Multiparametric magnetic resonance imaging (mpMRI) is pivotal in prostate cancer (PCa) diagnosis, but some clinically significant (cs) PCa remain undetected. This study aims to understand the pathological and molecular basis for csPCa visibility at mpMRI.
Marco Oderda   +12 more
wiley   +1 more source

A Retrospective Study on Pathologic Features and Racial Disparities in Prostate Cancer

open access: yesProstate Cancer, 2011
We reviewed more than 3,000 pathology reports on prostate cancer-related surgical specimens and analyzed racial disparities in histological and clinical features at the time of initial biopsy, diagnosis of prostate cancer, and prostatectomy, as well as ...
Steven A. Bigler   +2 more
doaj   +1 more source

The implication of initial 24-core transrectal prostate biopsy protocol on the detection of significant prostate cancer and high grade prostatic intraepithelial neoplasia

open access: yesInternational Brazilian Journal of Urology, 2011
PURPOSE: To assess the diagnostic value of an initial 24-sample transrectal ultrasound guided (TRUS) prostate biopsy protocol compared to the 10-core technique.
Michael Nomikos   +4 more
doaj   +1 more source

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