Results 131 to 140 of about 7,722 (240)

Progerin reduces LAP2α-telomere association in Hutchinson-Gilford progeria

eLife, 2015
Hutchinson-Gilford progeria (HGPS) is a premature ageing syndrome caused by a mutation in LMNA, resulting in a truncated form of lamin A called progerin.
Alexandre Chojnowski, Peh Fern Ong, Esther SM Wong, John SY Lim, Rafidah A Mutalif, Raju Navasankari, Bamaprasad Dutta, Henry Yang, Yi Y Liow, Siu K Sze, Thomas Boudier, Graham D Wright, Alan Colman, Brian Burke, Colin L Stewart, Oliver Dreesen   +15 more
doaj   +1 more source

Dysfunction of iPSC-derived endothelial cells in human Hutchinson–Gilford progeria syndrome [PDF]

, 2019
Children with Hutchinson–Gilford progeria syndrome (HGPS) succumb to myocardial infarction and stroke in their teen years. Endothelial dysfunction is an early event in more common forms of atherosclerosis. Endothelial pathobiology may contribute to HGPS,
Gianfranco Matrone (7241237), Shu Meng (316831), Anahita Mojiri (7241246), John P Cooke (7241249), Rajarajan A Thandavarayan (7241240), Brandon K Walther (7241243)   +5 more
core   +1 more source

The Geochemistry of the HGP-A Geothermal Well: A Review and an Update [PDF]

, 1988
The HGP-A geothermal well, located on the lower east rift system of Kilauea volcano, has provided steam and hot water to a 3 MWe wellhead generator facility on a continuous basis since December 1981.
openaire   +2 more sources

Cardiovascular Pathology in Hutchinson-Gilford Progeria: Correlation With the Vascular Pathology of Aging [PDF]

, 2010
Objective— Children with Hutchinson-Gilford progeria syndrome (HGPS) exhibit dramatically accelerated cardiovascular disease (CVD), causing death from myocardial infarction or stroke between the ages ...
Francis S. Collins, Richard Mitchell, Cecilia Blair, Jeanette K. Beers, Leslie Smoot, Thomas N. Wight, Elizabeth G. Nabel, Jason T. Machan, Birgit Funke, Renu Virmani, Leslie B. Gordon, Karima Djabali, Marie Gerhard-Herman, Ingrid Harten, Michael R. Erdos, Michelle Olive, Kan Cao, Robert Kutys   +17 more
core   +1 more source

Hutchinson-Gilford Progeria Syndrome

Online Journal of Health & Allied Sciences, 2014
Hutchinson-Gilford Progeria syndrome (HGPS) is a rare pediatric genetic syndrome associated with a characteristic aged appearance very early in life, generally leading to death in the second decade of life.
Gopal G, Belavadi GB
doaj  

HGP-A Wellhead Generator Proof-of-Feasibility Project (Well Test) at HGP-A Site Puna, Hawaii. Volume II. Technical Specifications [PDF]

, 1979
The purpose of this project is to provide and secure the well test system complete and ready for use. The project comprises the construction of a chemical treatment system (including caustic and hydrogen peroxide handling systems), new condensate piping, wellhead steam piping modifications, ancillary electrical systems and equipment, instrumentation ...
openaire   +2 more sources

Hutchinson–Gilford progeria syndrome: unraveling the genetic basis, symptoms, and advancements in therapeutic approaches

Therapeutic Advances in Rare Disease
Hutchinson–Gilford Progeria syndrome (HGPS) serves as a prominent model for Progeroid syndromes, a group of rare genetic disorders characterized by accelerated aging.
Akhil Arun, Athira Rejith Nath, Bonny Thankachan, M. K. Unnikrishnan   +3 more
doaj   +1 more source

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

The HGP: end of phase 1 [PDF]

Nature Genetics, 2002
openaire   +2 more sources

An Induced Pluripotent Stem Cell-derived Tissue Engineered Blood Vessel Model of Hutchinson-Gilford Progeria Syndrome for Disease Modeling and Drug Testing [PDF]

, 2018
Hutchison-Gilford Progeria Syndrome (HGPS) is a rare, accelerated aging disorder caused by nuclear accumulation of progerin, an altered form of the Lamin A gene.
Atchison, Leigh Joan
core