Results 131 to 140 of about 5,892 (251)

Hutchinson–Gilford progeria syndrome: unraveling the genetic basis, symptoms, and advancements in therapeutic approaches

Therapeutic Advances in Rare Disease
Hutchinson–Gilford Progeria syndrome (HGPS) serves as a prominent model for Progeroid syndromes, a group of rare genetic disorders characterized by accelerated aging.
Akhil Arun, Athira Rejith Nath, Bonny Thankachan, M. K. Unnikrishnan   +3 more
doaj   +1 more source

Endothelial YAP/TAZ activation promotes atherosclerosis in a mouse model of Hutchinson-Gilford progeria syndrome

The Journal of Clinical Investigation
Hutchinson-Gilford progeria syndrome (HGPS) is an extremely rare disease caused by the expression of progerin, an aberrant protein produced by a point mutation in the LMNA gene.
Ana Barettino, Cristina González-Gómez, Pilar Gonzalo, María J. Andrés-Manzano, Carlos R. Guerrero, Francisco M. Espinosa, Rosa M. Carmona, Yaazan Blanco, Beatriz Dorado, Carlos Torroja, Fátima Sánchez-Cabo, Ana Quintas, Alberto Benguría, Ana Dopazo, Ricardo García, Ignacio Benedicto, Vicente Andrés   +16 more
doaj   +1 more source

The HGP: end of phase 1 [PDF]

Nature Genetics, 2002
openaire   +2 more sources

Human immunodeficiency virus contains an epitope immunoreactive with thymosin alpha 1 and the 30-amino acid synthetic p17 group-specific antigen peptide HGP-30.

, 1987
Paul H. Naylor, Cartha W. Naylor, M. Badamchian, Seiji Wada, Goldstein Al, S S Wang, Di Sun, Arthur Thornton, P. S. Sarin   +8 more
openalex   +2 more sources

New therapeutic approaches to HGPS based on progerin inhibition [PDF]

, 2015
Camilla Pellegrini
openalex   +1 more source

Discordant Gene Expression Signatures and Related Phenotypic Differences in Lamin A- and A/C-Related Hutchinson-Gilford Progeria Syndrome (HGPS)

, 2011
Martina Plášilová, Chandon Chattopadhyay, Apurba Ghosh, Friedel Wenzel, Philippe Demougin, Christoph Noppen, Nathalie Schaub, Gabor Szinnai, Luigi Terracciano, Karl Heinimann   +9 more
openalex   +2 more sources

HGP-30, a synthetic analogue of human immunodeficiency virus (HIV) p17, is a target for cytotoxic lymphocytes in HIV-infected individuals.

, 1990
Adnane Achour, O Picard, Daniel Zagury, Prem S. Sarin, Robert C. Gallo, Paul H. Naylor, Allan L. Goldstein   +6 more
openalex   +1 more source

Complicações cardiovasculares e os impactos na qualidade de vida dos pacientes portadores da síndrome de Hutchinson-Gilford (HGPS)

, 2020
Pedro Antonio Rodrigues Dias, Maianna Viana Almeida Aguiar, André Rhodes Neves, Gabriela de Matos Reis, Íris Roberta Cruz Andrade, Isabella Pêgo Miranda Netto, Leonardo José Grossi Andrade, Mariane de Matos Reis, Mayra Heringer Motta Costa e Silva, Sara Eduarda Oliveira Da Cruz   +9 more
openalex   +2 more sources

Preliminary report on the location of producing layers of geothermal well HGP-A, Puna, Hawaii

, 1980
Ellen Kitamura
openalex   +2 more sources