Results 121 to 130 of about 7,722 (240)

Antimicrobial prescribing guidelines for feedlot cattle

Australian Veterinary Journal, Volume 104, Issue 7, Page 413-438, July 2026.
P Cusack, T Batterham, SW Page, GF Browning, JM Norris   +4 more
wiley   +1 more source

Differential stem cell aging kinetics in Hutchinson-Gilford progeria syndrome and Werner syndrome

Protein & Cell, 2018
Hutchinson-Gilford progeria syndrome (HGPS) and Werner syndrome (WS) are two of the best characterized human progeroid syndromes. HGPS is caused by a point mutation in lamin A (LMNA) gene, resulting in the production of a truncated protein product ...
Zeming Wu, Weiqi Zhang, Moshi Song, Wei Wang, Gang Wei, Wei Li, Jinghui Lei, Yu Huang, Yanmei Sang, Piu Chan, Chang Chen, Jing Qu, Keiichiro Suzuki, Juan Carlos Izpisua Belmonte, Guang-Hui Liu   +14 more
doaj   +1 more source

International consensus guidelines for scoring the histopathological growth patterns of liver metastasis

British Journal of Cancer, 2017
Background:Liver metastases present with distinct histopathological growth patterns (HGPs), including the desmoplastic, pushing and replacement HGPs and two rarer HGPs. The HGPs are defined owing to the distinct interface between the cancer cells and the
Pieter-Jan van Dam, E. P. van der Stok, L. Teuwen, G. G. Van den Eynden, M. Illemann, Sophia Frentzas, A. Majeed, R. Eefsen, R. R. J. Coebergh van den Braak, A. Lazaris, M. C. Fernández, B. Galjart, O. Laerum, R. Rayes, D. Grünhagen, Michelle Van de paer, Yves Sucaet, H. Mudhar, M. Schvimer, H. Nyström, M. Kockx, N. Bird, F. Vidal-Vanaclocha, P. Metrakos, È. Simoneau, C. Verhoef, L. Dirix, S. V. van Laere, Zu-hua Gao, P. Brodt, Andrew R Reynolds, P. Vermeulen   +31 more
semanticscholar   +1 more source

INVESTIGATION OF SMOOTH MUSCLE CELL DEATH AND GENOME INSTABILITY IN HUTCHINSON-GILFORD PROGERIA SYNDROME [PDF]

, 2016
Hutchinson–Gilford progeria syndrome (HGPS) is a severe human premature aging disorder caused by a lamin A mutant named progerin. Death occurs at a mean age of 13 y from cardiovascular problems.
Zhang, Haoyue
core   +1 more source

The Human Genome Project (HGP): dividends and challenges: a review.

Journal of College of Medicine, 2012
Background: Many disorders in man have been described as genetic or hereditary in nature and have defied absolute medical treatment and cure. Genomic studies have given profound insights into the genetic organization of many organisms including man.
openaire   +3 more sources

HGP-A wellhead generator proof-of-feasibility project [PDF]

, 1978
The HGP-A Wellhead Generator Proof-of-Feasibility Project consists of a nominal 3 Megawatt geothermal steam turbine electric power generating facility, the first geothermal power plant in Hawaii. The plant is being constructed as a research and development project to evaluate geothermal steam as a viable resource to be considered for larger commercial ...
openaire   +2 more sources

Mitophagy defect mediates the aging‐associated hallmarks in Hutchinson–Gilford progeria syndrome

Aging Cell
Hutchinson–Gilford progeria syndrome (HGPS) is a rare and fatal disease manifested by premature aging and aging‐related phenotypes, making it a disease model for aging.
Yingying Sun, Le Xu, Yi Li, Shunze Jia, Gang Wang, Xufeng Cen, Yuyan Xu, Zhongkai Cao, Jingjing Wang, Ning Shen, Lidan Hu, Jin Zhang, Jianhua Mao, Hongguang Xia, Zhihong Liu, Xudong Fu   +15 more
semanticscholar   +1 more source

Mechanisms of Early Arterial Stiffening and Reduced Smooth Muscle Contractility in the Premature Aging Disease Hutchinson-Gilford Progeria Syndrome [PDF]

, 2021
Hutchinson-Gilford Progeria syndrome (HGPS) is a rare premature aging disease in which children present with a rapid onset of clinical characteristics of aging.
von Kleeck, Ryan
core   +1 more source

Adenine base editing rescues pathogenic phenotypes in tissue engineered vascular model of Hutchinson-Gilford progeria syndrome

APL Bioengineering
The rare, accelerated aging disease Hutchinson-Gilford Progeria Syndrome (HGPS) is commonly caused by a de novo c.1824 C > T point mutation of the LMNA gene that results in the protein progerin.
Nadia O. Abutaleb, Xin D. Gao, Akhil Bedapudi, Leandro Choi, Kevin L. Shores, Crystal Kennedy, Jordyn E. Duby, Kan Cao, David R. Liu, George A. Truskey   +9 more
doaj   +1 more source

Chemical inhibition of NAT10 corrects defects of laminopathic cells

Science, 2014
Remodelin Nuclear Defects Deregulation of A-type lamin proteins leads to disorganization of chromatin structure and misshapen nuclei, which are believed to underlie the pathologies of various human diseases, including the premature aging disorder ...
Delphine Larrieu, S. Britton, Mukerrem Demir, Raphaël Rodriguez, S. Jackson   +4 more
semanticscholar   +1 more source