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An Overview of Hutchinson Gilford Progeria Syndrome (HGPS)
British Journal of Medicine and Medical Research, 2015 Hutchinson Gilford Progeria Syndrome (HGPS) is a rare genetic disorder. The disorder is characterized by premature aging, generally leading to death. The purpose of this article is to review Hutchinson Gilford Progeria Syndrome and its characteristics.
Maria Tsiligiri +3 more
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COMPUTATIONAL INVESTIGATION OF TRANSCRIPTOMIC AND GENETIC UNDERPINNINGs OF AGING AND HGPS [PDF]
, 2018 Normal aging is a complex process affecting everyone, and also a major risk factor for many complex diseases. Hutchinson Gilford progeria syndrome (HGPS) is a rare genetic disease with symptoms of aging at a very early age. There are some known and other
Wang, Kun
core +1 more source
Advanced Science, Volume 13, Issue 36, 29 June 2026.Programmable hydration pathways enable reconfigurable ionic thermoelectrics in polyquaternium hydrogels. By coupling microscopic solvation, mesoscale water channels, and macroscopic boundary control, hydration‐gated protonics decouples thermopower, response speed, and stability.
Zehao Zhao, Yun Shen, Dongyan Xu
wiley +1 more source
Expression of TRPV2 proteins in IMR90-iPSC-ECs and HGPS-iPSC-ECs. [PDF]
, 2014 (A and B), representative images (A) and data summary (B) of TRPV2 protein expression in IMR90- and HGPS-iPSC-ECs.
Nelson L. Tang (515416) +8 more
core +1 more source
BMC Medical Genomics, 2020 Background Parkinson’s Disease (PD) and Hutchinson-Gilford Progeria Syndrome (HGPS) are two heterogeneous disorders, which both display molecular and clinical alterations associated with the aging process.
Diana M. Hendrickx, Enrico Glaab
doaj +1 more source
A Wrinkle in Time: Premature Aging in HGPS and RD [PDF]
, 2008 The aging process can be accelerated by numerous cellular and molecular variables. Progeroid syndromes are one such example. The phenotypes of Hutchinson-Gilford Progeria Syndrome (HGPS) and Restrictive Dermopathy (RD) are both caused by an irregular ...
Fields, Nicole +4 more
core +1 more source
Transcripts and proteins significantly modulated in HGPS-derived cells versus healthy parental control cell lines. [PDF]
, 2018 Volcano plot representations of the RNAseq (A) and shotgun proteomics (B) analysis of the HGPS and Control cell lines. For RNAseq, a threshold of q-value = 0.05 was set for significance according the statistical package used for analysis.
Juan Fafián-Labora (5917748) +8 more
core +1 more source
Smart Medicine, Volume 5, Issue 3, June 2026.This study integrates transcriptomic, lipidomic, and metabolomic profiling of the heart, lung, skin, and serum from Hutchinson–Gilford progeria syndrome (HGPS) mouse models and human progeroid laminopathy (PL) cohorts. Through multi‐organ analyses, we reveal organ‐specific aging signatures, and importantly, cross‐species serum metabolomics identify ...
Lidan Hu +11 more
wiley +1 more source
Crosschecking of the genomic and proteomic results shows that HGPS present features of a metabolic disorder. [PDF]
, 2018 Representation of the modulation in HGPS versus Control cell lines of the transcripts detected as significant and those correlating with the proteomic approach (red dots in A).
Juan Fafián-Labora (5917748) +8 more
core +1 more source
Hydrology and geochemistry of a Hawaiian geothermal system: HGP-A [PDF]
, 1978 A water quality monitoring program of the Hawaii Geothermal Project well A (HGP-A) was conducted for downhole depth samples and continuous discharge samples in 1976 to 1977. The well water was slightly saline (about 5-10 percent ocean water) and nearly depleted of magnesium, but contained high concentrations of silica and sulfide.
Kroopnick, Peter M. +4 more
openaire +2 more sources