Results 151 to 160 of about 61,354 (196)

Association between IL1R1 rs2234650 Polymorphism in Patients with Acute Lymphoblastic Leukemia Infected with HHV-6A

Al-Rafidain Journal of Medical Sciences ( ISSN 2789-3219 )
Background: Everyone contracts the common infection known as human herpesvirus 6 (HHV-6). Particularly associated with encephalitis, human herpesvirus 6B (HHV-6B) poses a risk of morbidity and death to recipients of allogeneic hematopoietic stem cell ...
M. S. Ibrahim, Halah Dawood Salman, Aya Raed Alheany, S. Al-Alwany   +3 more
semanticscholar   +1 more source

Bis-tridentate Iridium(III) Complex with the N-Heterocyclic Carbene Ligand as a Novel Efficient Electrochemiluminescence Emitter for the Sandwich Immunoassay of the HHV-6A Virus.

Analytical Chemistry
Human herpesvirus type 6A (HHV-6A) can cause a series of immune and neurological diseases, and the establishment of a sensitive biosensor for the rapid detection of HHV-6A is of great significance for public health and safety.
Chenji Dai, Ziwang Mao, Yaoyao Xu, Junli Jia, Huamin Tang, Yibo Zhao, Yuyang Zhou   +6 more
semanticscholar   +1 more source

MHC2TA rs4774C and HHV‐6A active replication in multiple sclerosis patients

European Journal of Neurology, 2009
Background and purpose:  In a previous report, a strong gene–environment interaction between human herpesvirus 6A (HHV6A) active replication and MHC2TA rs4774C was demonstrated. The objectives of this study were: (i) to reappraise the association that was found in the previous study; (ii) to evaluate if MS patients with minor allele C and HHV‐6A active
R, Alvarez-Lafuente, A, Martinez, M, Garcia-Montojo, A, Mas, V, De Las Heras, M I, Dominguez-Mozo, C, Maria Del Carmen, M, López-Cavanillas, M, Bartolome, E, Gomez de la Concha, E, Urcelay, R, Arroyo   +11 more
openaire   +2 more sources

PCR Analysis of Human Telomeric Repeats Present on HHV-6A Viral Strains

Virus Genes, 1997
Human herpesvirus 6 (HHV-6) presents a perfect tandem array of human telomeric repeats (TRS) at both identical direct repeats (DR). Several researchers have reported a different TRS copy number by sequence analysis of HHV-6 DR's cloned fragments so it has been hypothesized that number of TRS is unstable. By PCR we show that the TRS copy number of U1102
MIRANDOLA, Prisco, RAVAIOLI T., CASSAI E.   +2 more
openaire   +2 more sources

HHV-6A and HHV-6B in Autoimmune Disease

2014
A role for HHV-6 has been proposed in several autoimmune disorders (ADs), including multiple sclerosis (MS), autoimmune connective tissue diseases, and Hashimoto's thyroiditis. There are several potential mechanisms by which HHV-6 might induce autoimmune responses.
openaire   +2 more sources

HHV-6A Drives Epigenetic Reprogramming via an EZH2–SIRT1 Axis to Sustain Mutant p53 and Reshape Oncogenic Inflammatory Signaling

Viruses
We previously demonstrated that human herpesvirus 6A infects papillary thyroid cancer cells (BCPAP), inducing molecular changes compatible with a tumor-promoting phenotype, including increased expression of R273H mutant TP53 (mutp53), upregulation of c ...
Rossella Benedetti, Michele Di Crosta, Alessia Stirparo, George Alexandru Aron, S. Mardente, R. Santarelli, R. Gonnella, M. S. Gilardini Montani, M. Cirone   +8 more
semanticscholar   +1 more source

Inherited HHV-6A reactivation linked to impaired immune reconstitution following hematopoietic stem cell transplantation

Haematologica
Not available.
L. Hannolainen, Heljä K M Lång, Lari Pyöriä, Kaisa Vepsäläinen, Svetlana Vakkilainen, K. Hedman, E. Kekäläinen, Z. Dickson, S. Ryhänen, Maria F Perdomo   +9 more
semanticscholar   +1 more source

HHV-6A, 6B, and 7: pathogenesis, host response, and clinical disease

2007
Human herpesvirus 6(HHV-6) is a human pathogen of emerging clinical significance. HHV-6 was first isolated from patients with lymphoproliferative disorders in 1986 (Salahuddin et al., 1986). HHV-6 isolates are classified into two groups as variants A(HHV-6A) and variant B(HHV-6B) (Schirmer et al., .
Yasuko Mori, Koichi Yamanishi
openaire   +1 more source

HHV-6A, 6B, and 7: molecular basis of latency and reactivation

2007
The human β-herpesvirus subfamily consists of human cytomegalovirus (HCMV), human herpesvirus 6 (HHV-6), and human herpesvirus 7 (HHV-7). HHV-6 and HHV-7 belong to the Roseolovirus genus of the β-herpesviruses, and the HHV-6 species are divided into two variants: HHV-6A and HHV-6B.
Kazuhiro Kondo, Koichi Yamanishi
openaire   +1 more source

HHV-6A, 6B, and 7: persistence in the population: epidemiology and transmission

2007
In common with all human herpesviruses, HHV-6 and HHV-7 establish lifelong infection following initial exposure and seroconversion. True latency as exemplified by HSV-1 and VZV, in which the genome is maintained in a transcriptionally restricted state, has not been conclusively shown for HHV-6 or HHV-7.
Vincent C. Emery, Duncan A. Clark
openaire   +1 more source