Results 111 to 120 of about 66,683 (210)
Clinico‐Epidemiological and Molecular Evidences for Reactivation of Herpesviruses in Dapsone‐Induced Hypersensitivity Reactions in Nepalese Leprosy Patients: An Observational Study [PDF]
Immun Inflamm DisThis study found clinical and molecular evidences for the presence of herpesvirus (HHV‐5 and HHV‐6) reactivation during dapsone‐induced hypersensitivity in Nepalese leprosy patients. Reflare of hypersensitivity symptoms occurred on average 20 days after culprit drug cessation.
Rana D +7 more
europepmc +2 more sources
Scientific Reports, 2018 Human herpesviruses 6-A and -B (HHV-6A, HHV-6B) are ubiquitous in human populations worldwide. These viruses have been associated with several diseases such as multiple sclerosis, Hodgkin’s lymphoma or encephalitis.
Marco Telford +2 more
doaj +1 more source
HHV-6B genome coverage in positive samples.
, 2012 Histograms of HHV-6B genome coverage generated by aligning reads with minimum 90% identity over the total read length to the genome. The depth of sequence coverage was calculated as the total Kb of aligned sequence per 1 Kb bin over the HHV-6B reference ...
Eva Harris (27355) +5 more
core +1 more source
PLoS PathogensHuman herpesvirus 6B (HHV-6B), a β-herpesvirus that significantly threatens immunocompromised individuals, currently lacks targeted antiviral therapies or vaccines. Glycoprotein B (gB), the primary mediator of membrane fusion during viral entry, is a key
Chu Xie +13 more
doaj +1 more source
LYMPHOPROLIFERATIVE SYNDROMES ASSOCIATED WITH HUMAN HERPESVIRUS-6A AND HUMAN HERPESVIRUS-6B
Mediterranean Journal of Hematology and Infectious Diseases, 2018 Human herpesvirus 6A and 6B (HHV-6A and HHV-6B) have been noted since their discovery for their T-lymphotropism. Although it has proven difficult to determine the extent to which HHV-6A and HHV-6B are involved in the pathogenesis of many diseases ...
Eva Eliassen +3 more
doaj +1 more source
Biochemical and Biophysical Research Communications - BBRC, 2017 Human herpesvirus 6B (HHV-6B) causes exanthema subitum in infants and is known to be mildly pathogenic. However, HHV-6B infection can induce febrile seizures in a high percentage of patients, and in rare cases, result in encephalitis.
M. Tamai +12 more
semanticscholar +1 more source
HHV-6-infected cells present HLA-B*08:01-restricted epitopes to CD8 T cells.
, 2018 (A, B) Analysis of IFN-γ secretion in response to infected cells. PHA-activated primary HLA-B*08:01-positive CD4 T cells were infected with HHV-6B strain HST (panel A) or HHV-6A strain U1102 (panel B), or remained uninfected.
Christoph Hübener (4751847) +7 more
core +1 more source
Human herpesvirus 6B U65 binds to histone proteins and suppresses interferon production
Journal of VirologyHuman herpesvirus 6B (HHV-6B), a member of the Betaherpesvirinae subfamily, is a T-lymphotropic virus that causes exanthem subitum and has been implicated in neuroinflammatory conditions such as multiple sclerosis.
Haokun Li +5 more
doaj +1 more source
, 2017 Quantitative PCR is the diagnostic pillar for clinical virology testing, and reference materials are necessary for accurate, comparable quantitation between clinical laboratories.
Linda Cook +12 more
core +1 more source
GP96 interacts with HHV-6 during viral entry and directs it for cellular degradation.
PLoS ONE, 2014 CD46 and CD134 mediate attachment of Human Herpesvirus 6A (HHV-6A) and HHV-6B to host cell, respectively. But many cell types interfere with viral infection through rapid degradation of viral DNA.
Bhupesh K Prusty +4 more
doaj +1 more source