Results 41 to 50 of about 78,725 (202)

Features of Human Herpesvirus-6A and -6B Entry [PDF]

Advances in Virology, 2012
Human herpesvirus-6 (HHV-6) is a T lymphotropic herpesvirus belonging to the Betaherpesvirinae subfamily. HHV-6 was long classified into variants A and B (HHV-6A and HHV-6B); however, recently, HHV-6A and HHV-6B were reclassified as different species ...
Takahiro Maeki, Yasuko Mori
doaj   +2 more sources

Multiple Sclerosis and Viruses: « Liaisons Dangereuses » [PDF]

Reviews in Medical Virology, Volume 36, Issue 6, November 2026.
ABSTRACT Multiple sclerosis (MS) is a complex, multifactorial neurodegenerative disease with an aetiology that is still partially elusive. Several risk factors are associated with MS development including genetic predisposition and various environmental stressors; however, recently, viral infections have gained significant attention as a crucial ...
Samanta Plavina, Daniela Malakovska, Jolanta Kalnina, Ilva Trapina, Elina Leonova, Mohammed Habib, Susanne Schifmann, Jegors Paramonovs, Nikolajs Sjakste, Yegor Vassetzky, Emmanuel Drouet, Natalia Paramonova   +11 more
wiley   +2 more sources

Comprehensive Viral Detection and Profiling of Plasma Cell‐Free RNA in Patients With Suspected Hemophagocytic Lymphohistiocytosis [PDF]

Journal of Medical Virology, Volume 98, Issue 9, September 2026.
ABSTRACT Hemophagocytic lymphohistiocytosis (HLH) is a severe, rapidly progressive disease. While viral infection is considered a common etiology of pediatric HLH, specific causative viruses other than the Epstein‐Barr virus (EBV) have been rarely identified.
Yuto Fukuda, Kazuhiro Horiba, Masanori Hashino, Shinji Kawabe, Hiroki Miura, Yoshiki Kawamura, Makito Tanaka, Takako Suzuki, Yuka Torii, Hideki Muramatsu, Yoshiyuki Takahashi, Tetsushi Yoshikawa, Jun‐ichi Kawada   +12 more
wiley   +2 more sources

A complex evolutionary relationship between HHV-6A and HHV-6B.

Virus Evol, 2019
Human betaherpesviruses 6A and 6B (HHV-6A and HHV-6B) are highly prevalent in human populations. The genomes of these viruses can be stably integrated at the telomeres of human chromosomes and be vertically transmitted (inherited chromosomally integrated HHV-6, iciHHV6). We reconstructed the population structure of HHV-6 and we show that HHV-6A genomes
Forni D, Cagliani R, Clerici M, Pozzoli U, Sironi M.   +4 more
europepmc   +3 more sources

Clinical and epidemiological features of infections caused by HHV-6A and HHV-6B [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2018
Objective. To determine the detection rates of HHV-6A and HHV-6B compared to other herpes viruses in children of different age groups. Materials and Methods.
Lysenkova M.Yu., Karazhas N.V., Rybalkina T.N., Veselovsky P.A., Burmistrov E.M., Boshyan R.E., Melekhina E.V., Svitich O.A., Muzyka A.D., Petukhova E.V., Gorelov A.V.   +10 more
doaj   +3 more sources

Associations of Inherited Chromosomally‐Integrated Human Herpesvirus 6 With Dementia Incidence, Inflammation, and Other Dementia Risk Factors in the UK Biobank [PDF]

Journal of Medical Virology, Volume 98, Issue 8, August 2026.
ABSTRACT The infection theory of dementia states that viral infections and chronic inflammation play a role in its pathogenesis. We aimed to test whether testing positive for inherited chromosomally‐integrated human herpesvirus 6 (iciHHV‐6) is associated with an increased dementia incidence, inflammation, and other dementia risk factors. We included n =
Zhong Qiya, Marko Mandic, Tim Waterboer, Xie Ruijie, Hermann Brenner, Ben Schöttker   +5 more
wiley   +2 more sources

Naturally processed HLA‐DR3‐restricted HHV‐6B peptides are recognized broadly with polyfunctional and cytotoxic CD4 T‐cell responses

European Journal of Immunology, 2019
Human herpes virus 6B (HHV‐6B) is a widespread virus that infects most people early in infancy and establishes a chronic life‐long infection with periodic reactivation.
Aniuska Becerra-Artiles, J. Cruz, J. Leszyk, J. Sidney, A. Sette, S. Shaffer, L. Stern   +6 more
semanticscholar   +2 more sources

HHV-6B infection, T-cell reconstitution, and graft-vs-host disease after hematopoietic stem cell transplantation [PDF]

Bone Marrow Transplant, 2018
Successful and sustained CD4+ T-cell reconstitution is associated with increased survival after hematopoietic cell transplantation (HCT), but opportunistic infections may adversely affect the time and extent of immune reconstitution. Human herpesvirus 6B
Tuan L. Phan, J. Pritchett, C. Leifer, D. Zerr, D. Koelle, D. Di Luca, P. Lusso   +6 more
semanticscholar   +2 more sources

Copy Number Heterogeneity, Large Origin Tandem Repeats, and Interspecies Recombination in Human Herpesvirus 6A (HHV-6A) and HHV-6B Reference Strains [PDF]

J Virol, 2018
Quantitative PCR is a diagnostic pillar for clinical virology testing, and reference materials are necessary for accurate, comparable quantitation between clinical laboratories.
Alexander L. Greninger, Pavitra Roychoudhury, N. Makhsous, Derek J. Hanson, Jill Chase, G. Krueger, Hong Xie, Meei-Li W. Huang, Laura R. Saunders, D. Ablashi, D. Koelle, L. Cook, K. Jerome   +12 more
semanticscholar   +2 more sources

Investigation of Inherited Chromosomally Integrated Human Herpesvirus-6A+ and -6B+ in a Patient with Ulipristal Acetate-Induced Fulminant Hepatic Failure

Viruses, 2021
Inherited chromosomally integrated (ici) human herpes virus 6 (HHV-6) is estimated to occur in 0.6–2.7% of people worldwide. HHV-6 comprises two distinct species: HHV-6A and HHV-6B. Both HHV-6A and HHV-6B integration have been reported. Several drugs are
Laure Izquierdo, Clémence M. Canivet, Eleonora De Martin, Teresa M. Antonini, Anne-Marie Roque-Afonso, Audrey Coilly, Claire Deback   +6 more
doaj   +1 more source