Results 41 to 50 of about 66,683 (210)

Investigation of Inherited Chromosomally Integrated Human Herpesvirus-6A+ and -6B+ in a Patient with Ulipristal Acetate-Induced Fulminant Hepatic Failure

Viruses, 2021
Inherited chromosomally integrated (ici) human herpes virus 6 (HHV-6) is estimated to occur in 0.6–2.7% of people worldwide. HHV-6 comprises two distinct species: HHV-6A and HHV-6B. Both HHV-6A and HHV-6B integration have been reported. Several drugs are
Laure Izquierdo, Clémence M. Canivet, Eleonora De Martin, Teresa M. Antonini, Anne-Marie Roque-Afonso, Audrey Coilly, Claire Deback   +6 more
doaj   +1 more source

Human herpesvirus 6B infection in mesial temporal lobe epilepsy: a meta-analysis

Acta Epileptologica, 2022
Background Whether human herpesvirus 6B (HHV-6B) can affect mesial temporal lobe epilepsy (MTLE) remains controversial. The present meta-analysis was aimed to evaluate whether HHV-6B is significantly associated with MTLE.
Jingyi Tong, Qin Zou, Sheng Wang, Jiaqi Liu, Rong Chen, Yongmin Chen, Wenjie Zhao, Lin Ma, Qifu Li   +8 more
doaj   +1 more source

Sensitive detection systems for infectious agents in xenotransplantation*

Xenotransplantation, EarlyView., 2020
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley   +1 more source

Variation in human herpesvirus 6B telomeric integration, excision, and transmission between tissues and individuals

eLife, 2021
Human herpesviruses 6A and 6B (HHV-6A/6B) are ubiquitous pathogens that persist lifelong in latent form and can cause severe conditions upon reactivation.
Michael L Wood, Colin D Veal, Rita Neumann, Nicolás M Suárez, Jenna Nichols, Andrei J Parker, Diana Martin, Simon PR Romaine, Veryan Codd, Nilesh J Samani, Adriaan A Voors, Maciej Tomaszewski, Louis Flamand, Andrew J Davison, Nicola J Royle   +14 more
doaj   +1 more source

Herpesvirus genome integration in whole-genome sequences of dementia and control cohorts. [PDF]

Alzheimers Dement
Abstract INTRODUCTION The infectious hypothesis suggests that microbes like herpesviruses may play a role in the pathogenesis of Alzheimer's disease (AD) and other related dementias through methods that may include viral genome integration. The occurrence of herpesvirus genome integration in dementia patients has not been thoroughly characterized ...
Piotrowski SL, Allnutt MA, Johnson K, Tanaka T, Ferrucci L, Morris H, Hardy J, PROSPECT Consortium, Ryten M, United Kingdom Brain Expression Consortium (UKBEC), Logroscino G, Troncoso J, Beach TG, Serrano GE, Cruchaga C, Dickson DW, Ross OA, Chiò A, International LBD Genomics Consortium, International ALS Genomics Consortium, Houlden H, American Genome Center, Dalgard CL, Ding J, Gibbs JR, Traynor BJ, Scholz SW, Jacobson S.   +27 more
europepmc   +2 more sources

HHV-6B is frequently found in the gastrointestinal tract in kidney transplantation patients. [PDF]

Transplant international : official journal of the European Society for Organ Transplantation, 2012
In immunosuppressed patients human herpesvirus 6 (HHV-6) reactivations are common. The aim of the study was to determine to which extent HHV-6 can be found in the gastrointestinal tract in kidney transplant recipients and in patients on chronic dialysis. The HHV-6 and cytomegalovirus (CMV) examinations were performed on gastro duodenal and colon biopsy
Lempinen, Marko, Halme, Leena, Arola, Johanna, Honkanen, Eero, Salmela, Kaija, Lautenschlager, Irmeli   +5 more
  +5 more sources

Comparative genomic, transcriptomic, and proteomic reannotation of human herpesvirus 6

BMC Genomics, 2018
Background Human herpesvirus-6A and -6B (HHV-6) are betaherpesviruses that reach > 90% seroprevalence in the adult population. Unique among human herpesviruses, HHV-6 can integrate into the subtelomeric regions of human chromosomes; when this occurs in ...
Alexander L. Greninger, Giselle M. Knudsen, Pavitra Roychoudhury, Derek J. Hanson, Ruth Hall Sedlak, Hong Xie, Jon Guan, Thuy Nguyen, Vikas Peddu, Michael Boeckh, Meei-Li Huang, Linda Cook, Daniel P. Depledge, Danielle M. Zerr, David M. Koelle, Soren Gantt, Tetsushi Yoshikawa, Mary Caserta, Joshua A. Hill, Keith R. Jerome   +19 more
doaj   +1 more source

High incidence and viral load of HHV-6A in a multi-centre kidney transplant cohort

Frontiers in Transplantation, 2023
Human herpesvirus 6 (HHV-6) is a common opportunistic pathogen in kidney transplant recipients. Two distinct species of HHV-6, HHV-6A and HHV-6B, have been identified, of which the latter seems to be dominant. However, it is unclear whether they increase
Arturo Blazquez-Navarro, Arturo Blazquez-Navarro, Toralf Roch, Toralf Roch, Patrizia Wehler, Patrizia Wehler, Sviatlana Kaliszczyk, Sviatlana Kaliszczyk, Chris Bauer, Constantin Thieme, Kamil S. Rosiewicz, Ulrik Stervbo, Ulrik Stervbo, Moritz Anft, Petra Reinke, Christian Hugo, Panagiota Zgoura, Richard Viebahn, Timm Westhoff, Michal Or-Guil, Nina Babel, Nina Babel   +21 more
doaj   +1 more source

Autopsy case of acute myeloid leukemia with human herpesvirus-6B (HHV-6B) encephalitis following cord blood transplantation and persistent HHV-6B DNA detection in the blood

Japanese Journal of Transplantation and Cellular Therapy
T. Hoshino, N. Hatsumi, Mikiya Kajita, A. Tsukada, Hiromasa Iino, S. Takada   +5 more
semanticscholar   +2 more sources

Nectin-2 Acts as a Viral Entry Mediated Molecule That Binds to Human Herpesvirus 6B Glycoprotein B

Viruses, 2022
Human herpesvirus 6B (HHV-6B) is a T-lymphotropic virus and the etiological agent of exanthem subitum. HHV-6B is present in a latent or persistent form after primary infection and is produced in the salivary glands or transmitted to this organ.
Hirohito Ogawa, Daisuke Fujikura, Hikaru Namba, Nobuko Yamashita, Tomoyuki Honda, Masao Yamada   +5 more
doaj   +1 more source