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HHV-6B ribonucleotide reductase sequesters NF-κB subunit p65 to inhibit innate immune responses. [PDF]
iScienceHuman herpesvirus 6B (HHV-6B) belongs to the genus Roseolovirus of the betaherpesvirus subfamily, causing exanthema subitum and encephalitis. Although viral ribonucleotide reductase (RNR) is conserved in betaherpesviruses, it has lost its enzymatic ...
Hirai M +5 more
europepmc +2 more sources
Image_3_DNA Sensors’ Signaling in NK Cells During HHV-6A, HHV-6B and HHV-7 Infection.TIF
, 2020 ObjectivesThe host DNA sensor proteins TLR9, STING, IFI16 are central signaling molecules that control the innate immune response to cytosolic nucleic acids. Here we propose to investigate how Natural killer (NK) cell infection by human herpesvirus (HHV)-
Antonella Rotola (441846) +9 more
core +1 more source
Infection and Drug Resistance, 2022 Jiao Meng,1,* Hongyan Ji,2,* Liting Chen,2 Aichun Liu1 1Hematology Department, Harbin Medical University Cancer Hospital, Harbin Medical University, Harbin, People’s Republic of China; 2Department of Hematology, Tongji Hospital, Tongji Medical ...
Meng J, Ji H, Chen L, Liu A
doaj
β-Herpesviruses in Febrile Children with Cancer
Emerging Infectious Diseases, 2008 We conducted a cross-sectional study of β-herpesviruses in febrile pediatric oncology patients (n = 30), with a reference group of febrile pediatric solid-organ transplant recipients (n = 9).
Stephanie Yee-Guardino +10 more
doaj +1 more source
Image_4_DNA Sensors’ Signaling in NK Cells During HHV-6A, HHV-6B and HHV-7 Infection.TIF
, 2020 ObjectivesThe host DNA sensor proteins TLR9, STING, IFI16 are central signaling molecules that control the innate immune response to cytosolic nucleic acids. Here we propose to investigate how Natural killer (NK) cell infection by human herpesvirus (HHV)-
Antonella Rotola (441846) +9 more
core +1 more source
, 2022 Within the family Herpesviridae, sub-family β-herpesvirinae, and genus Roseolovirus, there are only three human herpesviruses that have been described: HHV-6A, HHV-6B, and HHV-7.
Ruben Michael Ceballos (6749723) +3 more
core +1 more source
, 2023 Supplemental material, sj-pdf-1-imr-10.1177_03000605231204479 for HHV-6B- and HHV-7-associated choroiditis secondary to acute myelogenous leukemia: a case report by Jing Xu, Linjiang Chen, Tao Cen, Yuanping Zeng and Qiong Liu in Journal of International ...
Linjiang Chen (1370121) +4 more
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The mechanism, diagnosis and treatment of HHV-6B encephalitis
Rinsho Shinkeigaku, 2012 Human herpesvirus 6B (HHV-6B) is causative agent for exanthem subitum, which is common febrile illness in infant. This disease is generally benign and self-limited disease, however rarely causes several central nervous system complications. As various types of HHV-6B encephalitis has been demonstrated, pathophysiology of the disease would be complicate.
openaire +3 more sources
PLoS Pathogens, 2020 A unique glycoprotein is expressed on the virus envelope of human herpesvirus 6B (HHV-6B): the complex gH/gL/gQ1/gQ2 (hereafter referred to as the HHV-6B tetramer).
Mitsuhiro Nishimura +10 more
doaj +1 more source
Image_2_DNA Sensors’ Signaling in NK Cells During HHV-6A, HHV-6B and HHV-7 Infection.TIFF
, 2020 ObjectivesThe host DNA sensor proteins TLR9, STING, IFI16 are central signaling molecules that control the innate immune response to cytosolic nucleic acids. Here we propose to investigate how Natural killer (NK) cell infection by human herpesvirus (HHV)-
Antonella Rotola (441846) +9 more
core +1 more source