Results 21 to 30 of about 3,039 (157)

Outcomes of Haploidentical Stem Cell Transplant Recipients With HHV-6B Reactivation. [PDF]

Open Forum Infect Dis
Abstract Background Human herpesvirus 6B (HHV-6B) frequently reactivates following allogeneic stem cell transplant (alloHCT). Consensus guidelines note that haploidentical alloHCT may represent a high-risk population for which there is little evidence; this warrants further investigation.
Handley G, Yepes A, Eliassen E, Dominguez G, Pasikhova Y, Klinkova O, Baluch A, Febres-Aldana AJ, Alsina M, Elmariah H, Khimani F, Hansen DK, Freeman CL, Jain MD, Locke F, Lazaryan A, Liu HD, Mishra A, Mirza AS, Nishihori T, Ochoa L, Perez L, Pidala J, Puglianini OC, Nieder M, Perna F, Kim J, Bejanyan N, Faramand R.   +28 more
europepmc   +3 more sources

Investigation of Inherited Chromosomally Integrated Human Herpesvirus-6A+ and -6B+ in a Patient with Ulipristal Acetate-Induced Fulminant Hepatic Failure

Viruses, 2021
Inherited chromosomally integrated (ici) human herpes virus 6 (HHV-6) is estimated to occur in 0.6–2.7% of people worldwide. HHV-6 comprises two distinct species: HHV-6A and HHV-6B. Both HHV-6A and HHV-6B integration have been reported. Several drugs are
Laure Izquierdo, Clémence M. Canivet, Eleonora De Martin, Teresa M. Antonini, Anne-Marie Roque-Afonso, Audrey Coilly, Claire Deback   +6 more
doaj   +1 more source

Human herpesvirus 6B infection in mesial temporal lobe epilepsy: a meta-analysis

Acta Epileptologica, 2022
Background Whether human herpesvirus 6B (HHV-6B) can affect mesial temporal lobe epilepsy (MTLE) remains controversial. The present meta-analysis was aimed to evaluate whether HHV-6B is significantly associated with MTLE.
Jingyi Tong, Qin Zou, Sheng Wang, Jiaqi Liu, Rong Chen, Yongmin Chen, Wenjie Zhao, Lin Ma, Qifu Li   +8 more
doaj   +1 more source

Quantitative HHV-6B antigenemia test for the monitoring of transplant patients [PDF]

European Journal of Clinical Microbiology & Infectious Diseases, 2010
Human herpesvirus-6 (HHV-6) infection, mostly caused by variant B, is common after transplantation. Here, we report a new modified method using an HHV-6B glycoprotein IgG antibody, OHV-3, and attempt to quantify the HHV-6 antigenemia after liver transplantation.
Loginov, R., Karlsson, T., Höckerstedt, K., Ablashi, D., Lautenschlager, I.   +4 more
openaire   +4 more sources

Retraction to: A complex evolutionary relationship between HHV-6A and HHV-6B. [PDF]

Virus Evol, 2019
[This retracts the article DOI: 10.1093/ve/vez043.].
Forni D, Cagliani R, Clerici M, Pozzoli U, Sironi M.   +4 more
europepmc   +4 more sources

A complex evolutionary relationship between HHV-6A and HHV-6B.

Virus Evol, 2019
Human betaherpesviruses 6A and 6B (HHV-6A and HHV-6B) are highly prevalent in human populations. The genomes of these viruses can be stably integrated at the telomeres of human chromosomes and be vertically transmitted (inherited chromosomally integrated HHV-6, iciHHV6). We reconstructed the population structure of HHV-6 and we show that HHV-6A genomes
Forni D, Cagliani R, Clerici M, Pozzoli U, Sironi M.   +4 more
europepmc   +4 more sources

Variation in human herpesvirus 6B telomeric integration, excision, and transmission between tissues and individuals

eLife, 2021
Human herpesviruses 6A and 6B (HHV-6A/6B) are ubiquitous pathogens that persist lifelong in latent form and can cause severe conditions upon reactivation.
Michael L Wood, Colin D Veal, Rita Neumann, Nicolás M Suárez, Jenna Nichols, Andrei J Parker, Diana Martin, Simon PR Romaine, Veryan Codd, Nilesh J Samani, Adriaan A Voors, Maciej Tomaszewski, Louis Flamand, Andrew J Davison, Nicola J Royle   +14 more
doaj   +1 more source

Oral brincidofovir decreases the incidence of HHV-6B viremia after allogeneic HCT. [PDF]

Blood, 2020
Abstract Human herpesvirus 6B (HHV-6B) frequently reactivates after allogeneic hematopoietic cell transplantation (HCT). There are no randomized studies of antiviral treatments to prevent HHV-6B reactivation. Brincidofovir has high in vitro activity against HHV-6B and other DNA viruses, but its in vivo activity for HHV-6B has not been ...
Hill JA, Nichols WG, Marty FM, Papanicolaou GA, Brundage TM, Lanier R, Zerr DM, Boeckh MJ.   +7 more
europepmc   +3 more sources

Evaluation of a method to measure HHV-6B infection in vitro based on cell size. [PDF]

Virol J, 2018
Human herpesvirus 6 (HHV-6A and HHV-6B) infection of cell cultures can be measured by different methods, including immunofluorescence microscopy, flow cytometry, or quantification of virus DNA by qPCR. These methods are reliable and sensitive but require long processing times and can be costly.
Becerra-Artiles A, Santoro T, Stern LJ.
europepmc   +6 more sources

Sensitive detection systems for infectious agents in xenotransplantation*

Xenotransplantation, EarlyView., 2020
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley   +1 more source