Structural Models for Roseolovirus U20 And U21: Non-Classical MHC-I Like Proteins From HHV-6A, HHV-6B, and HHV-7. [PDF]
Front Immunol, 2022 Human roseolovirus U20 and U21 are type I membrane glycoproteins that have been implicated in immune evasion by interfering with recognition of classical and non-classical MHC proteins.
Weaver GC +4 more
europepmc +2 more sources
Quantitative HHV-6B antigenemia test for the monitoring of transplant patients [PDF]
European Journal of Clinical Microbiology & Infectious Diseases, 2010 Human herpesvirus-6 (HHV-6) infection, mostly caused by variant B, is common after transplantation. Here, we report a new modified method using an HHV-6B glycoprotein IgG antibody, OHV-3, and attempt to quantify the HHV-6 antigenemia after liver transplantation.
Loginov, R. +4 more
core +5 more sources
Corrigendum: Structural Models for Roseolovirus U20 And U21: Non-Classical MHC-I Like Proteins From HHV-6A, HHV-6B, and HHV-7. [PDF]
Front Immunol, 2022 [This corrects the article DOI: 10.3389/fimmu.2022.864898.].
Weaver GC +4 more
europepmc +2 more sources
TCR repertoire of human cytotoxic CD4 T cells responding to betaherpesviruses HHV-6B and HCMV. [PDF]
Front ImmunolBackground The role of CD4 T cells in the control of viral infections beyond their traditional helper activity has been increasingly recognized, and CD4 T cells with cytotoxic capacity have been reported for the nearly ubiquitous betaherpesviruses HCMV ...
Becerra-Artiles A +3 more
europepmc +2 more sources
A viral APOBEC3 antagonist distinguishes HHV-6A from HHV-6B [PDF]
Nature CommunicationsHuman herpesviruses exhibit diverse pathogenic outcomes and the molecular reasons are not fully understood. Human herpesvirus 6B (HHV-6B) causes exanthema subitum and encephalitis, whereas the closely related HHV-6A is typically asymptomatic.
Jun Arii +11 more
doaj +2 more sources
American Society for Transplantation and Cellular Therapy Series #9: Management of Human Herpesvirus 6B After Hematopoietic Cell Transplantation and Chimeric Antigen Receptor-T-Cell Therapy. [PDF]
Transplant Cell TherThe Practice Guidelines Committee and the Transplant Infectious Disease Special Interest Group of the American Society for Transplantation and Cellular Therapy developed guidelines focusing on human herpes virus 6B (HHV-6B).
Kampouri E +12 more
europepmc +2 more sources
2094. A prospective multicenter study of HHV-6B genomic DNA and gene transcription in paired bronchoalveolar lavage fluid and blood from HCT recipients [PDF]
Open Forum Infect Dis, 2022 Background We previously demonstrated frequent detection of HHV-6B DNA in bronchoalveolar lavage fluid (BALF) and its positive association with mortality in HCT recipients from 1992-2015 with lower respiratory tract disease (LRTD). Whether these findings
Joshua A. Hill +16 more
europepmc +2 more sources
Chronic persistent HHV-6B infection after sulfasalazine-induced DRESS with demonstration of HHV-6 encoded small noncoding RNAs (sncRNAs) in Crohn's-like colitis: Case report. [PDF]
Clin Case Rep, 2021 A sulfasalazine‐induced DRESS (Drug Reactivation with Eosinophilia and Systemic Symptoms) was complicated by a Crohn's‐like colitis. We demonstrated HHV‐6 reactivation with presence of HHV‐6 DNA and small noncoding RNA in colonic lesions.
Descamps V +5 more
europepmc +2 more sources
Role of HHV-6B Infection in Mesial Temporal Lobe Epilepsy. [PDF]
Pediatr Neurol Briefs, 2015 Investigators from Fujita Health University, Toyoake, and National Epilepsy Center, Shizuoka, Japan, studied the pathogenic role of HHV-6B in patients with mesial temporal lobe epilepsy (MTLE).
Millichap JJ, Millichap JG.
europepmc +6 more sources
Coinfection of human herpesviruses 6A (HHV-6A) and HHV-6B as demonstrated by novel digital droplet PCR assay. [PDF]
PLoS ONE, 2014 The human herpesviruses HHV-6A and HHV-6B have been associated with various neurologic disorders partly due to the detection of elevated viral DNA levels in patients compared to controls.
Emily C Leibovitch +6 more
doaj +2 more sources